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All Journal Indonesian Journal of Urology Indonesian Journal of Cancer STRING (Satuan Tulisan Riset dan Inovasi Teknologi)
RACHMAT BUDI SANTOSO, RACHMAT BUDI
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Computer Science & IT Health Professions Mathematics Medicine & Pharmacology Public Health

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Tingkat Kesintasan dan Faktor Prognostik Pasien Karsinoma Sel Ginjal di Rumah Sakit Cipto Mangunkusumo dan Rumah Sakit Kanker “Dharmais” SENO, DODDY HAMI; SANTOSO, RACHMAT BUDI; MOCHTAR, CHAIDIR; UMBAS, RAINY
Indonesian Journal of Cancer Vol 6, No 1 (2012): Jan - Mar 2012
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.115 KB)

Abstract

Karsinoma sel ginjal (KSG) mencakup 2-3% dari seluruh kasus kanker di seluruh dunia. Walaupun insidennya kecil, KSG mempunyai angka mortalitas yang besar. Berbagai studi mengenai faktor prognostik kesintasan pasien KSG menunjukkan hasil yang bervariasi. Penelitian ini bertujuan untuk mengetahui tingkat kesintasan KSG di Indonesia dan faktor prognostik yang berpengaruh terhadap kesintasan pasien KSG.Metode: penelitian ini dilakukan dengan menelusuri data registrasi pasien KSG yang telah menjalani operasi/biopsi pada Januari 1995 hingga Desember 2008 di Bagian Urologi Rumah Sakit Cipto Mangunkusumo dan Rumah Sakit Kanker “Dharmais”, Jakarta. Analisis kesintasan dilakukan dengan metode Kaplan-Meier dan analisis multivariat dilakukan dengan uji Cox proportional hazard regression.Hasil: sebanyak 81 pasien menjadi subjek penelitian. Median usia subjek 52 tahun (kisaran 6-83 tahun). Perbandingan laki-laki dan perempuan sebesar 3,2 : 1. Overall survival (OS) 5 tahun sebesar 22,2% dan rerata OS sebesar 64,3 bulan. Bila dikelompokkan berdasarkan Fuhrman grade, rerata disease-specific survival pada grade 1-2 adalah 84,9 bulan dan grade 3-4 adalah 37,8 bulan. Sedangkan bila dikelompokkan berdasarkan TNM staging, rerata disease-specific survival pada stage 1-2 (KSG lokal) 91,4 bulan; stage 3 (KSG lokal lanjut) 59,5 bulan; dan stage 4 (KSG metastatik) 29,7 bulan. Pada pasien KSG metastatik, overall survival 5 tahun sebesar 9,5%. Pada analisis multivariat, terdapat tiga faktor yang berhubungan dengan kesintasan, yaitu TNM staging (p=0,000), Fuhrman grade (p=0,040), dan hitung trombosit (p=0,034).Kesimpulan: overall survival pada kelompok pasien kami lebih rendah dibandingkan dengan negara lain karena sebagian besar subjek datang terlambat dan dengan ukuran tumor yang besar. Pada penelitian ini, terdapat tiga faktor yang berhubungan dengan kesintasan, yaitu TNM staging, Fuhrman grade, dan hitung trombosit. Kewaspadaan dan pengetahuan masyarakat mengenai KSG perlu ditingkatkan.Kata kunci: Fuhrman grade, sel jernih, trombositosis.
Systemic Management of Relapse Wilms Tumor After Radical Nephrectomy in An Adult Female, A Case Report PUTRA, IDA BAGUS OKA WIDYA; HARAHAP, EDWARD USFIE; SANTOSO, RACHMAT BUDI
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : Indonesian Journal of Cancer

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ABSTRACTWilms tumor (nephroblastoma) is rare in adults. We present a case of 28-year old female with Wilms tumor diagnosed with pre-operative abdominal magnetic resonance imaging, histopathological analysis and immunohistochemistry. She had relapse tumor two years after primary open radical nephrectomy. She was managed with chemotherapy with the ICE regimen (ifosfamide, carboplatin, and etoposide) for six cycles with partial response and excellent functional status. Keywords: ABSTRAKTumor Wilms (nefroblastoma) adalah kasus yang jarang ditemukan pada orang dewasa. Kami melaporkan satu kasus, pasien perempuan, 28 tahun dengan tumor Wilms yang didiagnosis dengan pemeriksaan magnetic resonance imaging pre-operasi, histopatologi, dan imunohistokimia. Pasien tersebut mengalami relaps dua tahun pasca-radikal nefrektomi. Pasien kemudian menjalani kemoterapi dengan regimen ICE (ifosfamid, karboplatin, dan etoposid) selama enam siklus dengan repons parsial dan status fungsional baik.
TUMOR IN HORSESHOE KIDNEYS: A CASE REPORT AND LITERATURE REVIEW Sutojo, Bobby; Bramono, Ikhlas Arief; Harahap, Edward Usfie; Santoso, Rachmat Budi; Treswari, Galuh Ayu; Putri, Rizky Ifandriani; Mahdi , Hardini Intan Setiawati
Indonesian Journal of Urology Vol 31 No 3 (2024)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v31i3.896

Abstract

Objective: This study aims to report a renal tumor in a horseshoe kidney successfully treated with an open left nephrectomy. Case(s) Presentation: A 3 years old girl with a lump in the left abdomen and intermittent hematuria was referred to our hospital. Whole abdominal contrast CT scan showed the presence of a left renal mass in a horseshoe kidney that infiltrates the left renal artery and is attached to the spleen. The patient underwent preoperative chemotherapy followed by surgical resection. Discussion: In a horseshoe kidney, renal tumors are uncommon. The limited kidney mobilization and access to the renal hilum and the abnormal and highly variable vasculature make surgical treatment of a tumor in a horseshoe kidney extremely difficult. Conclusion: Open surgery continues to be the treatment of choice for horseshoe kidney tumors due to their anatomical complexity, particularly in cases where the tumor is difficult to eradicate. Keywords: Renal tumor, horseshoe kidney, surgical management.
INTRACTABLE HEMATURIA IN BLADDER CANCER WITH UNILATERAL HIGH GRADE VESICOURETERAL REFLUX: A CONSERVATIVE APPROACH USING INTRAVESICAL FORMALDEHYDE INSTILLATION Rustandi, Reginald; Santoso, Rachmat Budi; Harahap, Edward Usfi; Bramono, Ikhlas Arief
Indonesian Journal of Urology Vol 32 No 2 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i2.930

Abstract

Objective: This study aims to report a case of intractable hematuria in a patient with bladder cancer after radiotherapy. Case(s) Presentation: This case reported a 41-year-old male with urothelial carcinoma of bladder who came to our hospital hematuria symptoms that arised four months after radiotherapy session. The patient was admitted several times with intractable hematuria along with low levels of hemoglobin, and diagnosed with cystitis radiation. Discussion: Voiding cystourethrogram (VCUG) showed unilateral high grade vesicoureteral reflux (VUR). The patient showed no sign of improvement after transarterial embolization (TAE), radiation, and high-dose of steroids. However, the symptoms finally resoluted after formaldehyde instillation. Conclusion: Patients with a history of bladder cancer who develop hematuria after radiotherapy should be evaluated promptly to exclude the possibility of recurrent disease. The administration of formaldehyde instillation could lower the symptoms of hematuria and maintain hemoglobin levels. Keywords: Intractabel hematuria, formaldehyde, bladder cancer.
Implementasi Keselamatan dan Kesehatan Kerja pada Aktivitas Karyawan Menggunakan Metode HIRARC Santoso, Rachmat Budi; Kusnadi, Kusnadi; Nugraha, Asep Erik
STRING (Satuan Tulisan Riset dan Inovasi Teknologi) Vol 10, No 1 (2025)
Publisher : Universitas Indraprasta PGRI Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30998/string.v10i1.28074

Abstract

Occupational safety and health are important factors at this time for employees so that they can do their work productively. This is done to reduce the impact of the risk of work accidents on employees and the company. The problem faced by the company is that there are work accidents that occur in mixer machines and production room areas that have an impact on employee safety and health. The HIRARC method is used in this study as a tool to identify work accidents that occur, assess how much impact is caused by work accidents, and provide control to handle so that work accidents do not occur. The purpose of this study is to reduce the occurrence of work accidents in the company to achieve zero accidents. The results of the PT ABC study showed that the activities carried out had a fairly high risk so that they could cause disorders in the human body to cause death and could be prevented by actions such as adding air ventilation and tightening the use of PPE (Personal Protective Equipment).
Co-Authors Bramono, Ikhlas Arief CHAIDIR MOCHTAR, CHAIDIR Doddy Hami Seno Harahap, Edward Usfi Harahap, Edward Usfie HARAHAP, EDWARD USFIE Kusnadi, Kusnadi Mahdi , Hardini Intan Setiawati Nugraha, Asep Erik PUTRA, IDA BAGUS OKA WIDYA Putri, Rizky Ifandriani Rainy Umbas Rustandi, Reginald Sutojo, Bobby Treswari, Galuh Ayu