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All Journal World Nutrition Journal Ophthalmologica Indonesiana Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Dicky L Tahapary
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Health Professions Medicine & Pharmacology Public Health

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Revisiting metabolic syndrome: The importance of weight management Dicky L Tahapary
World Nutrition Journal Vol. 6 No. S1 (2022): Selected conference proceedings of the Nutri Virtual Symposium 2022
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S1.0017

Abstract

Metabolic syndrome is an increasing major health problem worldwide, including Indonesia. More than one third of adult Indonesian population suffered from metabolic syndrome. Metabolic syndrome itself is actually a clustering of risk factors which increase the risk for diabetes mellitus and cardiovascular diseases in the future. Therefore, prompt management of metabolic syndrome is required to prevent the development of diabetes mellitus dan cardiovascular diseases.
Validation of Indonesian Graves’ Ophthalmopathy Quality of Life Questionnaire and Its Association with Clinical Activity and Severity of Graves’ Ophthalmopathy CECILIA ANGGRAINI; Syntia Nusanti; Muhammad Sidik; Dicky L Tahapary; Levina Chandra Khoe
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/v3z1dc46

Abstract

Abstract Introduction & Objectives : Graves' ophthalmopathy (GO) ocular abnormalities persisted even after treatment, negatively impacting the patient's psychological and social health. The Indonesian Graves' Ophthalmopathy Quality of Life (GO-QoL) Questionnaire has not been validated; hence it cannot measure patient quality of life in Indonesia, which is crucial to GO treatment. This objective of this study is providinga reliable Indonesian GO-QoL questionnaire and identifying an association between patient quality of life and clinical activity and severity of GO. Methods : The cross-sectional study ran from May through October 2022. Graves' ophthalmopathy and thyroid disease management were the inclusion criteria. Those who could not be reached by video call or controlled for two weeks for test-retest data collection were excluded. The process of questionnaire validation involves transcultural adaptation and cross-sectional design. The content validity index (CVI) and Cronbach's alpha assessed validity and reliability, respectively. Results : Content validity index (CVI) was 1.00 for the Indonesian GO-QoL questionnaire. Cronbach's alpha visual function subscale value was 0.971, while the appearance subscale value was 0.993, and the total score was 0.986. The appearance subscale and total score of GO patients' quality of life had a significant association with the clinical activity score (p<0.05) and disease severity (p<0.001). Conclusion : The Indonesian version of the GO-QoL questionnaire has high validity and reliability values. Patients' appearance and overall quality of life decreases with active Graves' ophthalmopathy. Graves' ophthalmopathy severity decreases quality of life on the appearance and overall subscales.
Mitigating Hungry Bone Syndrome: Case Reports on Best Practices After Parathyroidectomy Sarah Firdausa; Luki Kusumaningtyas; Dicky L Tahapary; Wismandari Wisnu; Tri Juli Edi Tarigan
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 2 No. 2 (2025): InaJEMD Vol. 2, No. 2
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v2i2.65

Abstract

Severe hyperparathyroidism caused by prolonged high levels of parathyroid hormone (PTH) can be managed by removing the gland. One of the critical complications related to parathyroidectomy is hungry bone syndrome (HBS), an emergency morbidity which may be fatal if not promptly and adequately managed. HBS is defined by a rapid and profound decline in serum calcium levels following surgery, as the bones avidly uptake calcium and phosphate in the absence of high PTH levels. It may present as worsened bone pain, carpopedal spasm, severe hypocalcemia, hypophosphatemia, and hypomagnesemia. This report highlights two patients who underwent parathyroidectomy and had different postoperative outcomes for HBS. The first case involves a 19-year-old male who had a history of recurrent fractures and bone pain. In 2019, he got a fracture from a fall, and in 2020, he experienced another fall leading to shoulder dislocation and further fractures. By late 2021, he was diagnosed with severe hyperparathyroidism due to parathyroid adenoma and the gland was removed. Two days post parathyroidectomy, he developed HBS. He was treated with calcium and vitamin D supplementation. Over two years of follow-ups, his bone density and mobility improved significantly. The second case involves a 46-year-old male with uncontrolled hypertension and chronic kidney disease stage 5 on hemodialysis, presenting with bone pain and deformities. This patient had a long-standing history of bone pain and fractures. He underwent a similar surgical intervention for tertiary hyperparathyroidism but did not develop HBS postoperatively. Careful perioperative monitoring of electrolytes, vigorous supplementation of calcium and vitamin D, and the use of antiresorptive therapies before surgery had been employed. These cases underline the variety of postoperative outcomes and the importance of tailored management strategies. Early intervention, appropriate surgical management, and aggressive postoperative supplementation are crucial to prevent and manage HBS in patients with severe hyperparathyroidism. Multidisciplinary approach and the utilization of various imaging modalities and intraoperative PTH monitoring are mandatory in managing such complex cases. Applying these approaches will reduce the risk of HBS while guaranteeing excellent postoperative care for individuals following parathyroidectomy.
Co-Authors CECILIA ANGGRAINI Levina Chandra Khoe Luki Kusumaningtyas Muhammad Sidik Sarah Firdausa Syntia Nusanti Tri Juli Edi Tarigan Wismandari Wisnu