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All Journal International Journal of Electrical and Computer Engineering Medical Journal of Indonesia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal Jurnal Penyakit Dalam Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Tri Juli Edi Tarigan
Universitas Indonesia
Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Electrical & Electronics Engineering Health Professions Medicine & Pharmacology Public Health

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PERBANDINGAN DENSITAS ENERGI LOW-LEVEL LASER THERAPY (LLLT) 10J/CM2 DENGAN 5 J/CM2 TERHADAP PENYEMBUHAN LUKA KAKI DIABETES Purwitasari Darmaputri; Nury Nusdwinuringtya; Nyoman Murdana; Tri Juli Edi Tarigan; Dewi Friska
Majalah Kedokteran Indonesia Vol 70 No 2 (2020): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volum
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jinma.v70i2.173

Abstract

Latar Belakang: Luka kaki diabetes merupakan masalah umum pasien diabetes melitus (DM). Salah satu terapi adjuvan yang dapat mempercepat penyembuhan luka adalah Low- Level Laser Therapy (LLLT), namun belum ada pedoman pasti mengenai dosisnya. Di Indonesia belum ada penelitian yang membandingkan densitas energi terhadap penyembuhan luka diabetes.Metode: Studi eksperimental ini dilakukan pada 28 subyek dengan luka kaki diabetes yang telah dirandomisasi. Kelompok A mendapat perawatan luka rutin dan LLLT 5J/cm2. Kelompok B mendapat perawatan luka rutin dan LLLT 10J/cm2. Dilakukan intervensi selama 4 minggu dengan frekuensi 2x/minggu.Hasil: Selisih ukuran luka setelah intervensi antara kelompok A dan B adalah 4.15 mm2 dan 7.5 mm2 (p=0.178). Total kecepatan pemulihan luka kelompok A dan B adalah 4.15(-10-34.5) mm2/4 minggu dan 7.5(-2.8-34) mm2/4 minggu (p=0.168). Kesimpulan: Pemberian LLLT dengan 5J/cm2 maupun 10J/cm2 tidak memberikan efek bermakna secara statistik terhadap penyembuhan luka kaki diabetes.
Effect of Green Tea Ingestion on Postprandial Triglyceride Levels in Young Women Trismiyanti Trismiyanti; Ida Gunawan; Tri Juli Edi Tarigan
World Nutrition Journal Vol. 1 No. 1 (2017)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V01i1.0006

Abstract

Development and characterization of an automated portable wound irrigation device for diabetic ulcers Muhammad Hanif Nadhif; Hanif Assyarify; Muhammad Irsyad; Em Yunir; Tri Juli Edi Tarigan; Angela Sarumpaet; Eni Iswati
International Journal of Electrical and Computer Engineering (IJECE) Vol 12, No 5: October 2022
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijece.v12i5.pp4746-4755

Abstract

Patients with diabetes mellitus may experience peripheral neuropathy and extremity system impairment, which may lead to ulceration if the treatments are delayed. Diabetic ulcers, unfortunately, are chronic, which require proper treatments, including debridement and bacterial removal using an irrigation device. To date, commercial irrigation devices included pulsed-lavage, bulb syringe, and gravity bags. Unfortunately, the devices have limitations in terms of portability, measurability, controllability, and disposability. To tackle the limitations, this study aims to design, fabricate, and characterize an automated portable wound irrigation device (Apdice), which is controllable non-disposable, and portable. The device was designed and fabricated using a lightweight construction, a rechargeable battery, and non-disposable materials to support the portability and non-disposable means. Meanwhile, the proportional-derivative-integral controller with its peripheral components were featured to enable controllability. Furthermore, the device was also tested regarding the contamination using a particle counter, and appeared to be contamination free. In short, Apdice showed a robust technological performance. However, it is also worth the try to test the contamination test against biological agents to guarantee the biocompatibility of the device.
Hubungan Heart Rate Variability dengan Global Longitudinal Strain pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Jakarta Hadi, Dwi Rendra; Rusdi, Lusiani; Tarigan, Tri Juli Edi; Mansjoer, Arif
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Introduction. Diabetes mellitus (DM) remains a major global health issue due to its direct consequences and complications, particularly cardiovascular complications. These complications are influenced by autonomic neuropathy, which can be assessed by Heart Rate Variability (HRV). Autonomic dysfunction is thought to impair heart function, which can potentially be predicted early by observing Global Longitudinal Strain (GLS). The relationship between HRV and GLS has not been extensively studied. Therefore, this study aimed to identify the relationship between HRV and GLS. Methods. A cross-sectional study with a population of adult type 2 DM patients residing in Jakarta in December 2020. HRV parameters included RR interval, Standard Deviation of NN Intervals (SDNN), Root Mean Square of Successive Difference (RMSSD), Low Frequency (LF), High Frequency (HF), and LF/HF ratio. Global longitudinal strain was analyzed using echocardiography. Results. Analysis was conducted on 167 samples. The mean value of GLS was -20.30 (SD 1.57). There were no correlation between RR interval (r = -0.07, p = 0.377), SDNN (r = -0.10, p = 0.189), RMSSD (r = -0.12, p = 0.098), LF (r = -0.003, p = 0.968), HF (r = -0.09, p = 0.21), and LF/HF ratio (r = -0.10, p = 0.189) with GLS. No association was found between hypertension, history of smoking, dyslipidemia, duration of diabetes, and HbA1C with GLS. Conclusion. There is no correlation between heart rate variability and global longitudinal strain in type 2 DM patients.
Primary Adrenal Insufficiency due to Tuberculosis Infection Pitfalls in Diagnosis and Management Ira Laurentika; Em Yunir; Tri Juli Edi Tarigan; Agnes Stephanie; Robert Shinto; Taufik Agung
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

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Abstract

Primary adrenal insufficiency (PAI) is a chronic condition in which both adrenal glands are not able to produce steroid hormones. In this article we reported a-20-year-old male with history of soft tissue tumor in thoracalregion and general hyperpigmentation of skin and mucous. Laboratory findings showed hypocortisolism and adrenal computed tomography (CT) scan showed bilateral enlargement of adrenal with multiple necrotic nodular lesion and calcification, suggesting adrenal metastasis or tuberculosis infection. The interferon gamma release assay (IGRA) and histopathology review of the specimen from soft tissue tumor in thoracal region showed confirmed the diagnosis of adrenal tuberculosis. Antituberculosis drugs were started, and hydrocortisone dose were frequently adjusted. Five months after therapy the patient is clinically improved with a minimal dose of steroid.
Secondary Hypogonadism in Recurrent Adamantinomatous Craniopharyngioma: Fertility Evaluation and Management Adeputri Tanesha Idhayu; Tri Juli Edi Tarigan; Em Yunir; Setyo Widi Nugroho; Eka Susanto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 2 (2024): InaJEMD Vol. 1, No. 2
Publisher : PP PERKENI

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Abstract

Craniopharyngioma is an intracranial tumor with pituitary hormone deficiencies and affects 40% of gonadotropins deficiency. Gonadotropin deficiency causes secondary hypogonadism and male infertility which need to investigation for male infertility therapy options. A 22-year-old man presented with history of intermittent headaches, visual impairment, mild left- side hemiparesis, and developed erectile dysfunction. On clinical examination, there was abnormal penile and testicular size. The radiological examination showed a solid intrasellar mass with cystic lesion. The histological diagnosis was adamantinoma Tous craniopharyngioma. The hormonal evaluation showed low testosterone level, LH and FSH, and semen analysis showed azoospermia. The human chorionic gonadotropin stimulation test showed testosterone increase times from baseline, but evaluation semen test remained azoospermia. Craniopharyngioma morbidity is associated with tumor related and or treatment-related risk factors such as hormone deficiencies. Pituitary hormone deficiencies have been reported in 54–100% of patients that affect secretion of growth hormone, gonadotropin, TSH and ACTH. Gonadotropin deficiency associated with infertility in men. In this case, gonadotropin deficiency was due to the tumor because the symptoms had developed before surgery. Hypogonadism in this case occurs after puberty and he willing to have offspring. The hormonal therapy is effective in restoring spermatogenesis relates to the regulatory of the hypothalamic pituitary gonadal axis. The administration of HCG alone or combined with FSH, restores spermatogenesis of patients with hypogonadotropic hypogonadism, with reported pregnancy rates of up to 65%. Gonadotropin stimulation therapy will be planned after ruling out seminal tract obstruction and testicular fibrosis. Infertility in secondary hypogonadism can be managed with hormone therapy, but a complete investigation is required before starting treatment to determine therapy options.
Detection of Small Lesion Insulinoma with 68Ga-DOTATATE PET/CT scan: A Case Report Irma Wahyuni; Tri Juli Edi Tarigan; Hendra Budiawan; Alvita Dewi; Rian Hidayatullah; Hasan Maulahela
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 2 No. 1 (2025): InaJEMD Vol. 2, No. 1
Publisher : PP PERKENI

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Abstract

Endogenous hyperinsulinism is a rare condition characterized by inappropriate insulin secretion, with insulinoma accounting for approximately 55% of cases. A 36-year-old woman presented with recurrent hypoglycemic episodes for 4.5 years, particularly in the morning, relieved by glucose intake. Laboratory findings during a supervised fasting test revealed a blood glucose of 44 mg/dL, elevated insulin (15 μIU/mL), C-peptide (2.27 ng/mL), proinsulin (53.1 pmol/L), and suppressed beta-hydroxybutyrate (0.1 mmol/L), indicating endogenous hyperinsulinemia. Initial imaging modalities including CT, MRI, and EUS failed to localize the lesion. The patient discontinued investigation but resumed a year later with nuclear imaging studies. A 99mTc-HYNIC-TOC scan was inconclusive, but subsequent ^68Ga-DOTATATE PET/CT at Hasan Sadikin Hospital revealed a somatostatin receptor-expressing nodule at the pancreatic head, consistent with insulinoma. Given the lesion's location and imaging findings, treatment options were discussed, including Whipple’s procedure versus radiofrequency ablation. Insulinomas are typically small, with 80% under 2 cm and 40% under 1 cm, often making localization challenging. While CT and MRI have detection rates of 70% and 86% respectively, the combination of CT and EUS may reach 100% sensitivity. In cases where conventional imaging is inconclusive, ^68Ga-DOTATATE PET/CT provides a valuable alternative, capable of detecting neuroendocrine tumors as small as 6 mm. This case highlights the critical role of nuclear medicine in localizing elusive insulinomas and guiding definitive treatment.
Perbandingan Densitas Energi Low-Level Laser Therapy (LLLT) 10J/cm2 dengan 5 J/cm2 terhadap Penyembuhan Luka Kaki Diabetes Darmaputri, Purwitasari; Nusdwinuringtya, Nury; Murdana, Nyoman; Tarigan, Tri Juli Edi; Friska, Dewi
Majalah Kedokteran Indonesia Vol 70 No 2 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.2-2020-173

Abstract

Background: Diabetic foot ulcer is a problem in patients with diabetes mellitus (DM). One adjuvant therapy that can enhance wound healing is Low-Level Laser Therapy (LLLT), but there is no established guideline regarding the dosage. In Indonesia, there has been no study comparing the energy density of LLLT on diabetic ulcer healingMethods: This is an experimental study on 28 subjects with a randomized diabetic foot ulcer. Group A received standard treatment of ulcer and LLLT 5J/cm2. Group B received standard treatment of ulcer and LLLT 10J/cm2.Results: The difference in wound size between group A and group B were 4.15 mm2 and 7.5 mm2 (p=0.178). The healing rate of group A and group B were 4.15 (-10-34.5) mm2/4 weeks and 7.5 (-2.8-34) mm2/4weeks (p=0.168).Conclusions: There was no statistically significant difference between the group receiving LLLT 5J/cm2 or 10 J/cm2 in diabetic foot ulcer healing.
Vitamin D levels and depression in type 2 diabetes mellitus patients: a cross-sectional study Putranto, Rudi; Adhiatma, Kresna; Tarigan, Tri Juli Edi; Rumende, Cleopas Martin; Shatri, Hamzah; Rengganis, Iris; Nugroho, Pringgodigdo; Rinaldi, Ikhwan
Medical Journal of Indonesia Vol. 32 No. 3 (2023): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.237005

Abstract

BACKGROUND The prevalence of type 2 diabetes mellitus (T2DM) is increasing and commonly accompanied by comorbidities, such as depression. Vitamin D levels have been associated with T2DM and depression although the mechanism is uncertain. This study aimed to compare vitamin D levels between patients with T2DM with and without depression in the Indonesian community, where such research is rare. METHODS This cross-sectional study was conducted at Cipto Mangunkusumo Hospital. The participants who met the inclusion criteria on an outpatient basis were screened for depression using the Beck Depression Inventory-II (BDI-II) questionnaire and then divided into 2 groups: patients with T2DM with (BDI-II ≥14) and without (BDI-II <14) depression. Both groups were examined for vitamin D levels using the ELISA method, and an analysis of the mean difference between both groups was performed. RESULTS Of 60 patients, 23 (38%) experienced depression. The median vitamin D levels were 21.8 ng/ml (IQR 14.9–26.6) in the depression group and 26.5 ng/ml (IQR 23.96–34.08) in the non-depression group (p = 0.001). After performing multivariate analysis with confounding variables, the adjusted OR of variables (sex, sun exposure score, and body mass index) was 1.123 (95% CI: 1.003–1.259; p = 0.045). CONCLUSIONS Vitamin D levels were significantly lower in patients with T2DM with depression. Future studies should be carried out to determine the benefits of vitamin D supplementation in patients with T2DM with depression and their pathophysiology.
Co-Authors Adeputri Tanesha Idhayu Adhiatma, Kresna Agnes Stephanie Harahap Alvita Dewi Angela Sarumpaet Arif Mansjoer Cleopas Martin Rumende Darmaputri, Purwitasari Dewi Friska Dewi Friska E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Eka Susanto Em Yunir, Em Eni Iswati Hadi, Dwi Rendra Hanif Assyarify Hasan Maulahela Hendra Budiawan Ida Gunawan Ikhwan Rinaldi Ira Laurentika Iris Rengganis Irma Wahyuni Kuntjoro Harimurti Lusiani Rusdi, Lusiani Maruhum B.H. Marbun Muhammad Hanif Nadhif Muhammad Irsyad Murdana, Nyoman Nury Nusdwinuringtya Nusdwinuringtya, Nury Nyoman Murdana Pringgodigdo Nugroho, Pringgodigdo Purwitasari Darmaputri Rian Hidayatullah Robert Shinto Rudi Putranto Setyo Widi Nugroho Taufik Agung Trismiyanti Trismiyanti