Article Per Year (5 Year)
p-Index From 2021 - 2026
0.659
P-Index
This Author published in this journals
All Journal ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar Current Research on Biosciences and Biotechnology
Muhammad Ikhlas Arsul
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Total phenolic, flavonoid, and antioxidant capacity of bajakah (Spatholobus littoralis Hassk) Muhammad Ikhlas Arsul; Nurfajri Syamsi; Nadila Putri; Nur Afiah Alfrianti Nur; Mukhriani; Nursalam Hamzah
Current Research on Bioscences and Biotechnology Vol. 4 No. 1 (2022)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2022.4.1/VRJ3X4LF

Abstract

The bajakah (Spatholobus littoralis Hassk.) is one of the typical plants from Kalimantan Island, which has potential as a drug, one of which using as an antioxidant is due to the secondary metabolites contained therein. The aims of the research are to estimate the total phenolic content, total flavonoid content, and antioxidant capacity of the bajakah by different methods. Extraction was carried out by reflux method using a solvent gradient of n-hexane, ethyl acetate, and ethanol 96%. Phenols and flavonoid content were calculated using spectroscopy. Antioxidant capacity was measured against ascorbic acid and Trolox using the CUPRAC, DPPH, and FRAP methods and reported as mg Trolox equivalent (TEAC) and ascorbic acid equivalent (AEAC) per gram extract. The ethanol extract showed the highest antioxidant capacity for the CUPRAC and FRAP methods, the n-hexane extract for the DPPH method on both varieties of bajakah tampala. Each method provides significantly different antioxidant capacity values. The CUPRAC and FRAP methods found the highest antioxidant capacity in the white variety of bajakah ethanol extract. Meanwhile, in the DPPH method, saw the highest antioxidant capacity in the red variety of n-hexane bajakah extract. DPPH and CUPRAC give a positive correlation with TPC, where CUPRAC assay produced higher values than FRAP and DPPH assays.
Xenograft Models for Preclinical Assessment of Anticancer Therapies: A Comprehensive Review Ebrahim sadaqa; Muhammad Ikhlas Arsul
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.38677

Abstract

Introduction: Xenograft models play a pivotal role in preclinical studies for assessing the efficacy of anticancer medications. In this comprehensive review, we present an overview of current advancements and future prospects in xenograft research, focusing on their significance in guiding drug development and clinical translation. Aim: Our aim is to conduct an in-depth review of xenograft models, their utility in evaluating anticancer drug effectiveness and ultimately improve patient outcomes. Methods We conducted an in-depth literature search using databases such as ScienceDirect, Google Scholar and PubMed with keywords including "xenograft model, cancer CDX PDX." We then reviewed and analyzed relevant studies that utilized xenograft models in order to highlight key findings and contributions made through such models. Results: Our analysis showcases the essential role of xenograft models in assessing the efficacy of anticancer drugs. We discuss the benefits and limitations of these models, emphasizing their importance in guiding drug development and clinical decision-making. Conclusion: Xenograft models remain invaluable tools in preclinical cancer research despite their inherent limitations, with researchers continually striving to refine and enhance these models to ensure their reliability in an ever-evolving field of cancer therapeutics. Utilizing xenograft models allows researchers to evaluate anticancer drug activity more accurately while striving for improved patient outcomes.
Formulasi Biskuit Ekstrak Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Terhadap Penurunan Kadar Kolesterol pada Mencit (Mus musculus) Nursyamsi Dhuha; Muhammad Ikhlas Arsul; Gebyanti Swara
Jurnal Farmasi UIN Alauddin Makassar Vol 12 No 2 (2024): Jurnal Farmasi Edisi Desember
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jfuinam.v12i2.53168

Abstract

Pendahuluan: Rosella merupakan salah satu tanaman obat tradisional yang memiliki berbagai khasiat diantaranya meredakan batuk, sebagai antidiabetes, antikolesterol, antibakteri, dan meningkatkan sistem imun. Bahan aktif yang terdapat pada bunga rosella adalah grossypeptin, antosianin, gluside hibiscin dan flavonoid. senyawa tersebut diketahui dapat menurunkan kadar kolesterol. Tujuan: Penelitian ini bertujuan untuk mengetahui potensi penurunan kadar kolesterol dengan menggunakan ekstrak Bunga Rosella yang dibuat dalam bentuk biskuit. Metode: Penelitian ini menggunakan mencit yang dibagi kedalam empat kelompok. Kadar kolesterol ditingkatkan dengan induksi kuning telur. Bunga rosela dibuat dalam bentuk biskuit kemudian diberikan pada mencit secara peroral. Hasil: Setelah pemberian selama tujuh hari, kadar kolesterol masing-masing mencit menunjukkan penurunan yang signifikan. Kesimpulan: Biskuit ekstrak bunga rosella dapat menurunkan kadar kolesterol pada mencit. Kata kunci: Bunga rosella, biskuit, antikolesterol
Co-Authors Ebrahim sadaqa Gebyanti Swara Mukhriani, Mukhriani Nadila Putri Nur Afiah Alfrianti Nur Nurfajri Syamsi Nursalam Hamzah Nursyamsi Dhuha