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All Journal Jurnal Mandala Pharmacon Indonesia ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Pengabdian kepada Masyarakat
Nurfadilah
Department of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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The Effectiveness of Ethanol Extract Botto’-Botto’ Leaves (Chromolaena Odorata L.) in Transdermal Patch Formulation as Medication in Wound Healing Anshari Masri; Nurfadilah; Zulkifli; Muhammad Taufiq Duppa; Muhammad Subhan A Sibadu
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.31676

Abstract

Botto'-botto' plant (Chromolaena odorata L.) is a native Indonesian plant that belongs to the Asteraceae family and is known to have a high flavonoid content and antioxidant activity that can slow down the oxidation process to prevent infection while accelerating wound healing. botto'-botto' is designed as a patch to make it easier to use and provide the most effective treatment. The purpose of this study was to make a patch preparation and to investigate its effects on wound healing. The patch was formulated and then tested for physical properties (organoleptic, superficial pH, moisture loss, thickness, weight uniformity, and folding endurance test) and their activity against wounds experimentally using rabbits as an animal test with 4 (four) treatment groups, namely the control group, botto'-botto’ patch 10%, 20%, and 30%. Wounds were made with an area of 2 cm and 0.1 cm deep. The wound was plastered with a patch and observed for 18 days. Data were analyzed statistically using ANOVA. The results showed that the patch formulation of leaves extract botto'-botto’ affects for wound healing in rabbits significantly, with p<0.05. Furthermore, the patch formulation of ethanol extract botto’-botto’ with a concentration of 30% had the best and fastest healing effect among all formulas. KEYWORDS: Botto’-botto’, wound healing, transdermal patch
EDUKASI PEMANFAATAN OBAT TRADISIONAL SEBAGAI ASI BOOSTER Andi Ulfah Magefirah Rasyid; Sri Widyastuti; Fityatun Usman; Zulkifli Zulkifli; Syafruddin Syafruddin; Muhammad Taufiq Duppa; Muhammad Guntur; Nurfadilah Nurfadilah; Rahmadani Rahmadani; Sulaiman Sulaiman; Anshari Masri; Ainun Jariah; Andri Anugrah Pratama; Haryanto Haryanto
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 7: Desember 2022
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v2i7.3956

Abstract

Various types of plants in the surrounding environment that have medicinal properties are many that can be obtained and utilized, and can even be planted themselves, which are known as family medicinal plants. This medicinal plant has begun to be widely studied, especially Indonesian Native Medicinal Plants, because it has relatively small side effects when compared to modern medical drugs. Communities in Pattallassang District generally have various types of medicinal plants that are planted in their yards and are often used as alternative treatments for certain types of diseases or as supplements, one example being breastfeeding boosters, which are very much needed by mothers in carrying out their activities. exclusive breastfeeding program. To support the exclusive breastfeeding program, various efforts must be made, one of which is the use of breastfeeding boosters, which is expected to help increase the production of breast milk. The purpose of the community service activity is to increase understanding of the importance of exclusive breastfeeding and to provide education about the use of several plants that have the potential as breastfeeding boosters in terms of processing techniques and more rational ways of using them. This service is carried out at Merpati Posyandu, Pattallassang Village, Pattallassang District, Takalar Regency. The method of providing community service activities is by providing counseling and demonstrations on how to process and manufacture good traditional medicines. The results of the activity assessment showed that participants gained knowledge about the types of traditional medicines, especially breastfeeding boosters, along with good processing and manufacturing methods of traditional medicines.
PENYULUHAN KEPADA MASYARAKAT TENTANG PENCEGAHAN DEMAM BERDARAH DENGUE (DBD) MELALUI PSN 3M PLUS DI DESA BONTOALA KECAMATAN PALLANGGA KABUPATEN GOWA Syafruddin Syafruddin; Nurfadilah Nurfadilah; Yulfina Wahdania; Jangga Jangga; Sulaiman Sulaiman; Zulkifli Zulkifli; Andi Ulfah Magefirah Rasyid; Fityatun Usman; Sri Widyastuti; Muhammad Guntur; Muhammad Taufiq Duppa; Rahmadani Rahmadani; Ansari Masri; Ainun Jariah
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 9: February 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v2i9.4834

Abstract

Demam berdarah Dengue (DBD) merupakan penyakit yang disebabkan oleh virus Dengue dan ditularkan oleh nyamuk Aedes aegypti dan Aedes albopictus. Penyakit DBD ini erat sekali hubungannya dengan masalah kebersihan lingkungan. Metode penanggulangan yang banyak diterapkan saat ini adalah tindakan pencegahan antara lain program pengendalian vektor. Jumlah kasus DBD baik secara nasional maupun di lingkup Kabupaten Gowa yang masih tinggi. Pencegahan penyakit DBD yang dapat dilakukan secara rutin dan telah direkomendasikan oleh WHO adalah Pemberantasan Sarang Nnyamuk 3M plus. Adapun rincian 3M tersebut terdiri dari menguras tempat penampungan air, menutup tempat penampungan air, dan mengubur barang-barang bekas yang dapat menjadi tempat penampungan air, sedangkan yang dimaksud dengan plus adalah menaburkan bubuk larvasida, menggunakan obat nyamuk, menggunakan kelambu saat tidur, memelihara ikan pemakan jentik nyamuk, menanam tanaman pengusir nyamuk, mengatur cahaya dan ventilasi dalam rumah, menghindari kebiasaan menggantung pakaian di dalam rumah. Perilaku PSN 3M plus ini dilaksanakan masyarakat 1 kali dalam seminggu di masing-masing rumah, lalu untuk daerah yang lebih luas / lapangan dilaksanakan kerja bakti 1 kali sebulan untuk memberantas sarang nyamuk demam berdarah. Evaluasi akhir dilakukan untuk mengetahui manfaat kegiatan penyuluhan yaitu mitra mampu melaksanakan kegiatan yang telah diikuti dengan menghitung persentase mitra yang mampu melaksanakan pengendalian vektor DBD melalui PSN 3M Plus secara berkelanjutan, serta mampu menerapkan ilmu yang didapat dalam penyluhan ini, baik dilingkungan umum maupun di lingkungan tempat tinggal masing-masing.
Penentuan Nilai SPF (Sun Protecting Factor) Sunscreen Gel Ekstrak Daun Cengkeh (Syzygium aromaticum) Secara In Vitro Nurfadilah Nurfadilah; Fityatun Usman; Andi Ulfah Magefirah Rasyid; Zulkifli Zulkifli; Yulfina Wahdaniah
Jurnal Mandala Pharmacon Indonesia Vol. 9 No. 2 (2023): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v9i2.352

Abstract

Sunscreen disebut salah satu jenis kosmetik baik secara fisik maupun kimia dapat memberikan efek penghambatan efek penetrasi sinar ultraviolet ke dalam kulit. Dimana adanya paparan sinar secara berlebih dan terus menerus mengakibatkan jaringan epidermis kulit kurang mampu melawan berbagai efek negatifnya seperti penuaan dini, penggelapan pada warna kulit, kulit terbakar sinar matahari, bahkan dapat memicu dan meningkatkan risiko kanker kulit. Sediaan sunscreen sangat diperlukan dalam membantu mekanisme alami pertahanan tubuh dalam  melindungi dari paparan tinggi radiasi ultraviolet. Efek perlindungan terhadap sinar UV dapat diperoleh dari bahan yang tinggi kandungan antioksidan. Daun cengkeh dengan kandungan flavanoid dan eugenol memiliki efek antioksidan tinggi yang mampu melindungi kulit dari paparan dan bahaya dari sinar UV. Penelitian ini bertujuan untuk menentukan karakteristik fisik dan nilai SPF dari sediaan sunscreen gel dengan ekstrak daun cengkeh (Syzygium aromaticum). Ekstraksi maserasi menggunakan pelarut etanol 96% yang dipekatkan menggunakan alat rotary evaporator dan penentuan nilai SPF menggunakan metode spektofotomeri UV-Vis. Ekstrak etanol daun cengkeh discreening fitokimia dan menunjukkan warna orange kemerahan menandakan positif kandungan flavonoid. Sunscreen Gel ekstrak etanol daun cengkeh dibuat 5 formula dengan perbedaan pada konsentrasi ekstrak etanol daun cengkeh, yaitu 0, 1, 2, 4 dan 8 % menggunakan basis karbopol. Formula kemudian diuji karakteristik fisik dan nilai SPFnya. Kelima formula gel ekstrak etanol daun cengkeh memenuhi persyaratan dalam uji karakteristik sifat fisik yaitu organoleptis, homogenitas, daya sebar, pH, dan viskositas. Nilai SPF untuk formula 1, 2, 3, 4 dan 5 yaitu sebesar 0,19; 0,53; 2,05; 3,83; 2,16 dan berpotensi melindungi kulit dari radiasi UVB.
Co-Authors Ainun Jariah Andi Ulfah Magefirah Rasyid Andri Anugrah Pratama Ansari Masri Anshari Masri Anshari Masri Fityatun Usman Haryanto Haryanto Jangga Muhammad Guntur Muhammad Subhan A Sibadu Muhammad Taufiq Duppa Muhammad Taufiq Duppa Rahmadani Rahmadani Sri Widyastuti Sulaiman Sulaiman Syafruddin Syafruddin Yulfina Wahdania Yulfina Wahdaniah Zulkifli Halid