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All Journal Journal of Nutrition College Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Siti Surdijati, Siti
Department of Medical Pharmacy, Faculty of Pharmacy, Unika Widya Mandala Surabaya
Environmental Science Health Professions Medicine & Pharmacology

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Studi Penggunaan Antiemetik pada Pasien Demam Tifoid Rawat Inap di RSUD Kabupaten Sidoarjo Wardhani, Hety Setya; Surdijati, Siti; Hasmono, Didik
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 4 No. 1 (2017)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v4i1.2175

Abstract

Typhoid fever is an infection of the small intestine caused by Salmonella thypi bacteria with symptoms of fever at night. This disease is a contagious disease that can affect many people and is still a health problem, especially in developing countries. This study aims to analyze patterns of antiemetic use in typhoid fever patients. This research was conducted at Sidoarjo District General Hospital using a retrospective method in the period of January 1 to December 31, 2015. The sample was typhoid fever patients who were treated at the Sidoarjo District Hospital. The results obtained using the Health Medical Record (RMK) of patients who have been validated, 161 patients was detected and only 30 patients who is using antiemetic therapy. The antiemetic used is ondansetron. Ondansetron in single dose (3x4mg) iv used in 7 patients (23%) and (3x8mg) iv in 23 patients (77%). The duration of ondansetron use in typhoid fever patients in Sidoarjo District Hospital ≤ 2 days was 10 patients and ≥ 2 days was 20 patients. Antiemetics used were in accordance with the guidelines and no Drug Related Problems (DRPs) were obtained in typhoid fever patients as seen from their interactions with other drugs, the interval of administration, frequency of administration, duration of treatment, and dose of administration.
Studi Penggunaan Omeprazole pada Pasien Sirosis Hati dengan Hemetamesis Melena Rawat Inap di RSUD Kabupaten Sidoarjo Wiranata, I Made; Hasmono, Didik; Surdijati, Siti
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 4 No. 1 (2017)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v4i1.2177

Abstract

Liver cirrhosis is a process of liver cell damage which later becomes fibrosis tissue. Then, the occurrence of liver structural distortion and increased vascularization to the liver resulting in varicose veins or dilation of blood vessels in the gastrointestinal and esophageal areas. Patients with esophageal varices, there is a risk of bleeding from esophageal rupture, the undergone hematemesis (vomiting of blood) and melena (blackish defecate). The therapies used to reduce gastrointestinal bleeding are gastric ulcers drugs such as H2Ras and PPI. The study aimed to determine the pattern of omeprazole use in liver cirrhosis patients with hematemesis melena. The method used was an observational retrospective study in medic record data patients. Sampling was done by consecutive sampling, the period of Juli 1, 2015 until Descember 31, 2015. The results obtained from the study were single use of omeprazole with a dose of 2x40mg/i.v used the most by 22 patients (73.3%). The use of omeprazole with a dose of 2x40mg/i.v combined with other gastric ulcer drugs was 7 patients (23.3%), omeprazole with ranitidin 6 patients, omeprazole with antacid for 1 patient. The use of omeprazole with a dose of 2x40mg was replaced with ranitidin 2x25mg/ml was 1 patient (3.3%). The use of omeprazole given in liver cirrhosis patients with hematemesis melena at the Inpatient Installation of Regional Hospital of Sidoarjo, related dose, route, frequency, interval, and duration of giving was in appropriate with the guidelines contained in the National Formulary.
Pola Penggunaan Ranitidine pada Pasien HIV & AIDS di UPIPI RSUD DR. Soetomo Surabaya Nurohmawati, Weni; Triyono, Erwin Astha; Surdijati, Siti; Jaya, Halim Priyahau
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 4 No. 2 (2017)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v4i2.2182

Abstract

HIV is a retrovirus that attacks CD4 lymphocyte cells. AIDS is a retrovirus disease caused by infection with retrovirus HIV-1 or HIV-2 which causes opportunistic diseases, secondary neoplasms and neurological abnormalities. In patients with HIV & AIDS often experience gastrointestinal disorders such as nausea and vomiting caused by side effects of the use of antiretroviral or due to other factors. Ranitidine is an H2 inhibitory receptor that will selectively and reversibly reduce excess gastric acid secretion. In this study ranitidine was used as a stress ulcer prophylaxis in hospitalized patients. This study aims to display ranitidine therapy data including type, dose, route of drug administration, prevalence, duration of use and qualitative analysis of interactions associated with medical record data at UPIPI RSUD Dr. Soetomo Surabaya. The research method used was observational prospectively on patient medical record with HIV & AIDS. Sampling was carried out by consecutive sampling period from November 1, 2016 to December 31, 2016. The results of this study give information that ranitidine was most widely used for stress ulcer prophylaxis therapy in hospitalized patients in UPIPI RSUD Dr. Soetomo Surabaya in a dose of 50mg / 2ml with a frequency of 2x1 while for oral ranitidine with a dose of 150mg / tablet with a frequency of 2x1. The use of ranitidine on HIV & AIDS patients in UPIPI RSUD Dr Soetomo Surabaya, related to dosage, route, frequency, interval, and duration of administration is in accordance with the existing guidelines.
Studi Penggunaan Antihipertensi Golongan Angiotensin Receptor Blockers Terhadap Pasien Gagal Ginjal Kronik Stadium V di Rumah Sakit Bhayangkara Surabaya Bura, Ursula Dua Klowe; Hasmono, Didik; Surdijati, Siti; Hartono, Ruddy
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 4 No. 2 (2017)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v4i2.2185

Abstract

Chronic renal failure is functional or structural kidney damage for more than 3 (three) months with or without a decrease in the Glomerular Filtration Rate (GFR), manifested as one of the pathological abnormalities or a sign of kidney damage, including blood or urine composition abnormalities or radiology abnormalities. In addition, chronic renal failure is also defined as a condition of GFR value of less than 60 ml / minute / 1.73 m2, for more than 3 (three) months with or without kidney damage. One of the risk factor for chronic renal failure is hypertension. The purpose of antihypertensive administration is to prevent further damage to other organs, and also to reduce blood pressure in patients with chronic renal failure with a target of ≤ 140 mmHg. Angiotensin Receptor Blockers (ARB) is a first-line therapy used to reduce blood pressure so that it can delay kidney damage. The purpose of this study was to determine the pattern of antihypertensive drug use in the ARB class in patients with stage V chronic renal failure at Bhayangkara Hospital in Surabaya which was associated with clinical and laboratory data. The study was conducted observationally with a descriptive research design and retrospective data collection. The results showed that those who met the inclusion criteria were 30 patients using antihypertensive ARB therapy, where the highest number of sexes were 67% male and 33% female, the highest populations at the age of 31-70 years, the highest populations was 90% for ARB use and other antihypertensive drug and a single ARB use of 10 %, the most common combination ofantihypertensive group is ARB and Calsium Channel Blocker (CCB) 41%. The patient’s blood pressure mostly meets the target of ≤ 140 mmHg.
Studi Penggunaan Carboplatin untuk Penderita Kanker Payudara di RUMKITAL Dr. Ramelan Surabaya Giovani, Alfin; Hasmono, Didik; Surdijati, Siti; Semedi, Joko
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 7 No. 1 (2020): Februari
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v7i1.2393

Abstract

Cancer is an abnormal growth of new cells that grow beyond normal limits. Cancer can metastasize by attacking parts of the body and spread to other organs. The prevalence of cancer Indonesian’s people in 2013 is estimated at 347,792. Breast cancer is the most common cancer in women with a percentage of 23%. Breast cancer is the second most common cancer with death after cervical cancer. Breast cancer is divided according to histologic subtype to Ductal Carcinoma in Situ (DCIS) and Lobular Carcinoma in Situ (LCIS). Carboplatin is a platinum analog cancer drug that belongs to the class of antineoplastic agents. Carboplatin doses used in AUC 6 (i.v) breast cancer chemotherapy for 1 cycle with 21 days to 6 cycle times. This research was conducted observasional with descriptive research design and retrospective data retrieval. The purpose of this study was to know the profile of carboplatin as an anti-cancer drug that is expected to provide safe treatment. This research was conducted at Dr. RUMKITAL Ramelan Surabaya with the number of inclusion of 30 patients in the period January 1, 2017 - December 31, 2017. From the results of this study obtained the use of single carboplatin as much as 7% and a combination of 93%. Patients with chemotherapy administered without surgery and surgery were 73% and 27%, respectively. Toxicity of nausea and vomiting happen as much as 42% and pain as much as 19%.
Pengaruh Komunikasi, Informasi dan Edukasi (KIE) terhadap Tingkat Pengetahuan Pasien Pediatri Penyakit Diare di Puskesmas “X” Wilayah Surabaya Timur Missa, Margareta Maria Alacoque; Surdijati, Siti; Trisnani, Retno
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 7 No. 2 (2020): Oktober
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v7i2.2794

Abstract

Diare merupakan salah satu masalah kesehatan yang masih sering menjadi Kejadian Luar Biasa ( KLB ) karena dapat menyebabkan kematian. Penyebab utama kematian diare adalah dehidrasi akibat kehilangan cairan dan elektrolit melalui feses. Penyakit diare masih menjadi masalah global dengan derajat kesakitan dan kematian yang tinggi di berbagai negara terutama di negara berkembang. Penelitian ini bertujuan untuk mengetahui pengaruh dari Komunikasi Informasi dan Edukasi (KIE) terhadap tingkat pengetahuan pasien penyakit diare di Puskesmas “X” Wilayah Surabaya Timur periode Maret hingga Agustus 2019. Penelitian bersifat deskriptif dan Analisis metode paired sample T test dengan pengambilan data secara purposive sampling. Sumber data adalah pasien pediatri penyakit diare dengan rentang usia 0-17 tahun. Hasil penelitian dari 40 responden yang memenuhi kriteria inklusi, yaitu jumlah responden berjenis kelamin laki-laki (7,5%) dan perempuan (92,5%), sebagian besar berusia 31-35 tahun (47,5%) dan 25-30 tahun (27,5%). Hasil penelitian menunjukkan bahwa dari 40 responden yang memenuhi kriteria inklusi sebelum KIE diperoleh tingkat pengetahuan baik (15%), tingkat pengetahuan cukup (77 %) , dan tingkat pengetahuan kurang sebesar (7,5 %). Sesudah KIE diperoleh tingkat pengetahuan baik (75%), dan tingkat pengetahuan cukup (25%). Berdasarkan hasil penelitian terdapat hubungan antara tingkat pengetahuan dengan pemberian Komunikasi Informasi dan Edukasi (KIE) terhadap pasien pediatri penyakit diare yang dilakukan di puskesmas “X” Wilayah Surabaya Timur.
Co-Authors Bura, Ursula Dua Klowe Didik Hasmono Erwin Astha Triyono Giovani, Alfin Hartono, Ruddy Jaya, Halim Priyahau Lisa Soegianto Missa, Margareta Maria Alacoque Nurohmawati, Weni Octavia, Stefani Kartika Octavia, Stefani Kartika Pambudi, Rien Esti Semedi, Joko Trisnani, Retno Wardhani, Hety Setya Wijaya, Hendy Wiranata, I Made