Syed Azhar Syed Sulaiman, Syed Azhar Syed
School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

PROBLEM PEMILIHAN OBAT PADA PASIEN RAWAT INAP GERIATRI DI RSUP DR. SARDJITO YOGYAKARTA Rahmawati, Fita; Ellykusuma, Nany Yusuf; Pramantara, I Dewa Putu; Sulaiman, Syed Azhar Syed
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 4, No 1 (2008)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Old age is associated with chronic diseases and disabilities, which in turn require multiple medications. This often complicate diagnosed and appropriate drug therapy. The aim of the study was to determine types and number of inappropriate drug in geriatric patients in Bougenville Ward Dr. Sardjito Hospital Yogyakarta. Research type is descriptive. Data taken prospectively during two period, January to February 2006 and Agust to October 2006. The study was conducted in 100 geriatric patients hospitalized with inclusion criteria 65 years old and above and admission into Bougainville ward (interne department) RSUP Dr. Sardjito Hospital, Yogyakarta. Data collecting was conducted through medical record then adjustment of inappropriate drug of choice was identified by pharmacist-physician discussion. Evaluation of the data was carried out descriptively. The result of the study showed that inappropriate drug of choice occurred in 48 cases. This problem include more effective drug available 12 cases, contraindication present 15 cases, dosage form inappropriate 2 cases, condition refractory to drug 1 case, drug not indicated (unsafe) for condition 9 cases, patient received unnecessary multiple drug combination 9 cases. The finding of our study support pharmacist in collaboration between physician-pharmacist-nurse can effectively reduce incidence of Drug Related Problems in geriatric patient. ABSTRAK Penelitian ini bertujuan untuk mengetahui jumlah dan persentase Drug-Related Problems (DRPs) yang terjadi pada pasien geriatri di Bangsal Bougenville IRNA I RSUP Dr. Sardjito Yogyakarta. Penelitian bersifat deskriptif, pengambilan data dilakukan secara prospektif pada 100 pasien dengan kriteria pasien berumur lebih dari 60 tahun dan menjalani rawat inap di bangsal Bougenville IRNA I bagian Penyakit Dalam RSUP Dr. Sardjito. Data diambil pada 2 periode waktu yaitu bulan Januari – Februari 2006 dan bulan Agustus-Oktober 2006. Identifikasi Drug Related Problem (DRP) terkait dengan pemilihan obat yang tidak tepat dilakukan melalui diskusi dengan klinisi. Analisis data selanjutnya dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa problem pemilihan obat yang tidak tepat terjadi sejumlah 48 kasus. Problem ini meliputi obat yang diterima pasien bukan merupakan obat yang paling tepat 12 kasus, pasien menerima kombinasi obat yang tidak diperlukan sebanyak 9 kasus, obat dikontraindikasikan pemakaiannya untuk pasien sejumlah 15 kasus, obat tidak aman bagi kondisi pasien 9 kasus, bentuk sediaan tidak tepat 2 kasus, obat yang digunakan sudah merupakan obat yang paling tepat namun pada kasus tersebut tidak efektif sejumlah 1 kasus. Untuk mengurangi kejadian Drug-Related Problems (DRPs) pada pasien geriatri diperlukan peningkatan peran aktif farmasis serta kerja sama diantara tenaga medis dalam memberikan pelayanan kesehatan.
PROBLEM PEMILIHAN OBAT PADA PASIEN RAWAT INAP GERIATRI DI RSUP DR. SARDJITO YOGYAKARTA Rahmawati, Fita; Ellykusuma, Nany Yusuf; Pramantara, I Dewa Putu; Sulaiman, Syed Azhar Syed
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 4, No 1 (2008)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Old age is associated with chronic diseases and disabilities, which in turn require multiple medications. This often complicate diagnosed and appropriate drug therapy. The aim of the study was to determine types and number of inappropriate drug in geriatric patients in Bougenville Ward Dr. Sardjito Hospital Yogyakarta. Research type is descriptive. Data taken prospectively during two period, January to February 2006 and Agust to October 2006. The study was conducted in 100 geriatric patients hospitalized with inclusion criteria 65 years old and above and admission into Bougainville ward (interne department) RSUP Dr. Sardjito Hospital, Yogyakarta. Data collecting was conducted through medical record then adjustment of inappropriate drug of choice was identified by pharmacist-physician discussion. Evaluation of the data was carried out descriptively. The result of the study showed that inappropriate drug of choice occurred in 48 cases. This problem include more effective drug available 12 cases, contraindication present 15 cases, dosage form inappropriate 2 cases, condition refractory to drug 1 case, drug not indicated (unsafe) for condition 9 cases, patient received unnecessary multiple drug combination 9 cases. The finding of our study support pharmacist in collaboration between physician-pharmacist-nurse can effectively reduce incidence of Drug Related Problems in geriatric patient. ABSTRAK Penelitian ini bertujuan untuk mengetahui jumlah dan persentase Drug-Related Problems (DRPs) yang terjadi pada pasien geriatri di Bangsal Bougenville IRNA I RSUP Dr. Sardjito Yogyakarta. Penelitian bersifat deskriptif, pengambilan data dilakukan secara prospektif pada 100 pasien dengan kriteria pasien berumur lebih dari 60 tahun dan menjalani rawat inap di bangsal Bougenville IRNA I bagian Penyakit Dalam RSUP Dr. Sardjito. Data diambil pada 2 periode waktu yaitu bulan Januari – Februari 2006 dan bulan Agustus-Oktober 2006. Identifikasi Drug Related Problem (DRP) terkait dengan pemilihan obat yang tidak tepat dilakukan melalui diskusi dengan klinisi. Analisis data selanjutnya dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa problem pemilihan obat yang tidak tepat terjadi sejumlah 48 kasus. Problem ini meliputi obat yang diterima pasien bukan merupakan obat yang paling tepat 12 kasus, pasien menerima kombinasi obat yang tidak diperlukan sebanyak 9 kasus, obat dikontraindikasikan pemakaiannya untuk pasien sejumlah 15 kasus, obat tidak aman bagi kondisi pasien 9 kasus, bentuk sediaan tidak tepat 2 kasus, obat yang digunakan sudah merupakan obat yang paling tepat namun pada kasus tersebut tidak efektif sejumlah 1 kasus. Untuk mengurangi kejadian Drug-Related Problems (DRPs) pada pasien geriatri diperlukan peningkatan peran aktif farmasis serta kerja sama diantara tenaga medis dalam memberikan pelayanan kesehatan.
PROBLEM PEMILIHAN OBAT PADA PASIEN RAWAT INAP GERIATRI DI RSUP DR. SARDJITO YOGYAKARTA Rahmawati, Fita; Ellykusuma, Nany Yusuf; Pramantara, I Dewa Putu; Sulaiman, Syed Azhar Syed
Jurnal Farmasi Indonesia Vol 4, No 1 (2008)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v4i1.5

Abstract

Old age is associated with chronic diseases and disabilities, which in turn require multiple medications. This often complicate diagnosed and appropriate drug therapy. The aim of the study was to determine types and number of inappropriate drug in geriatric patients in Bougenville Ward Dr. Sardjito Hospital Yogyakarta. Research type is descriptive. Data taken prospectively during two period, January to February 2006 and Agust to October 2006. The study was conducted in 100 geriatric patients hospitalized with inclusion criteria 65 years old and above and admission into Bougainville ward (interne department) RSUP Dr. Sardjito Hospital, Yogyakarta. Data collecting was conducted through medical record then adjustment of inappropriate drug of choice was identified by pharmacist-physician discussion. Evaluation of the data was carried out descriptively. The result of the study showed that inappropriate drug of choice occurred in 48 cases. This problem include more effective drug available 12 cases, contraindication present 15 cases, dosage form inappropriate 2 cases, condition refractory to drug 1 case, drug not indicated (unsafe) for condition 9 cases, patient received unnecessary multiple drug combination 9 cases. The finding of our study support pharmacist in collaboration between physician-pharmacist-nurse can effectively reduce incidence of Drug Related Problems in geriatric patient. ABSTRAK Penelitian ini bertujuan untuk mengetahui jumlah dan persentase Drug-Related Problems (DRPs) yang terjadi pada pasien geriatri di Bangsal Bougenville IRNA I RSUP Dr. Sardjito Yogyakarta. Penelitian bersifat deskriptif, pengambilan data dilakukan secara prospektif pada 100 pasien dengan kriteria pasien berumur lebih dari 60 tahun dan menjalani rawat inap di bangsal Bougenville IRNA I bagian Penyakit Dalam RSUP Dr. Sardjito. Data diambil pada 2 periode waktu yaitu bulan Januari â?? Februari 2006 dan bulan Agustus-Oktober 2006. Identifikasi Drug Related Problem (DRP) terkait dengan pemilihan obat yang tidak tepat dilakukan melalui diskusi dengan klinisi. Analisis data selanjutnya dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa problem pemilihan obat yang tidak tepat terjadi sejumlah 48 kasus. Problem ini meliputi obat yang diterima pasien bukan merupakan obat yang paling tepat 12 kasus, pasien menerima kombinasi obat yang tidak diperlukan sebanyak 9 kasus, obat dikontraindikasikan pemakaiannya untuk pasien sejumlah 15 kasus, obat tidak aman bagi kondisi pasien 9 kasus, bentuk sediaan tidak tepat 2 kasus, obat yang digunakan sudah merupakan obat yang paling tepat namun pada kasus tersebut tidak efektif sejumlah 1 kasus. Untuk mengurangi kejadian Drug-Related Problems (DRPs) pada pasien geriatri diperlukan peningkatan peran aktif farmasis serta kerja sama diantara tenaga medis dalam memberikan pelayanan kesehatan.
PROBLEM PEMILIHAN OBAT PADA PASIEN RAWAT INAP GERIATRI DI RSUP DR. SARDJITO YOGYAKARTA Rahmawati, Fita; Ellykusuma, Nany Yusuf; Pramantara, I Dewa Putu; Sulaiman, Syed Azhar Syed
Jurnal Farmasi Indonesia Vol 4, No 1 (2008)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v4i1.6

Abstract

Old age is associated with chronic diseases and disabilities, which in turn require multiple medications. This often complicate diagnosed and appropriate drug therapy. The aim of the study was to determine types and number of inappropriate drug in geriatric patients in Bougenville Ward Dr. Sardjito Hospital Yogyakarta. Research type is descriptive. Data taken prospectively during two period, January to February 2006 and Agust to October 2006. The study was conducted in 100 geriatric patients hospitalized with inclusion criteria 65 years old and above and admission into Bougainville ward (interne department) RSUP Dr. Sardjito Hospital, Yogyakarta. Data collecting was conducted through medical record then adjustment of inappropriate drug of choice was identified by pharmacist-physician discussion. Evaluation of the data was carried out descriptively. The result of the study showed that inappropriate drug of choice occurred in 48 cases. This problem include more effective drug available 12 cases, contraindication present 15 cases, dosage form inappropriate 2 cases, condition refractory to drug 1 case, drug not indicated (unsafe) for condition 9 cases, patient received unnecessary multiple drug combination 9 cases. The finding of our study support pharmacist in collaboration between physician-pharmacist-nurse can effectively reduce incidence of Drug Related Problems in geriatric patient. ABSTRAK Penelitian ini bertujuan untuk mengetahui jumlah dan persentase Drug-Related Problems (DRPs) yang terjadi pada pasien geriatri di Bangsal Bougenville IRNA I RSUP Dr. Sardjito Yogyakarta. Penelitian bersifat deskriptif, pengambilan data dilakukan secara prospektif pada 100 pasien dengan kriteria pasien berumur lebih dari 60 tahun dan menjalani rawat inap di bangsal Bougenville IRNA I bagian Penyakit Dalam RSUP Dr. Sardjito. Data diambil pada 2 periode waktu yaitu bulan Januari â?? Februari 2006 dan bulan Agustus-Oktober 2006. Identifikasi Drug Related Problem (DRP) terkait dengan pemilihan obat yang tidak tepat dilakukan melalui diskusi dengan klinisi. Analisis data selanjutnya dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa problem pemilihan obat yang tidak tepat terjadi sejumlah 48 kasus. Problem ini meliputi obat yang diterima pasien bukan merupakan obat yang paling tepat 12 kasus, pasien menerima kombinasi obat yang tidak diperlukan sebanyak 9 kasus, obat dikontraindikasikan pemakaiannya untuk pasien sejumlah 15 kasus, obat tidak aman bagi kondisi pasien 9 kasus, bentuk sediaan tidak tepat 2 kasus, obat yang digunakan sudah merupakan obat yang paling tepat namun pada kasus tersebut tidak efektif sejumlah 1 kasus. Untuk mengurangi kejadian Drug-Related Problems (DRPs) pada pasien geriatri diperlukan peningkatan peran aktif farmasis serta kerja sama diantara tenaga medis dalam memberikan pelayanan kesehatan.
Relationship between Hemodialysis Duration, Hemoglobin, and Creatinine of Hemodialysis Erythropoietin Vaccinated Patients with Covid-19 Munuarti Muhawia; Ramatillah, Diana Laila; Sulaiman, Syed Azhar Syed
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1960

Abstract

Chronic Kidney Disease (CKD) is an abnormality of kidney function and structure, where the glomerular filtration rate is less than 60 mL/min/1.73 m² and kidney damage lasts more than 3 months. The purpose of the study was to clarify the relationship between the length of hemodialysis with Hemoglobin and Creatinine in Hemodialysis patients. The research design used was prospective and retrospective cohort. Retrospective for the period January 2022-January 2023, while for the prospective period February-April 2024. The sample size in this study using convinienvce sampling technique was 259. The results of the study showed that there was a significant relationship between the length of hemodialysis with hemoglobin and creatinine levels with a P-value of 0.001 <0.05.
In Silico Analysis of Tea Leaf Compounds Targeting Inflammatory Pathways and Acne-Related Genes Sumarlin, La Ode; Nurbaya, Siti; Wulandari, Meyliana; Sulaiman, Syed Azhar Syed
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46468

Abstract

Acne (Acne vulgaris) is a chronic skin disease affected by Cutibacterium acnes infection and inflammatory pathways that trigger innate immune responses, such as inflammasome activation. The expression of inflammation-related genes plays a critical role in acne pathogenesis and immune modulation. This study aims to identify compounds from tea leaves (Camellia sinensis var. assamica) that can treat acne by influencing the expression of inflammatory-related genes through in silico analysis. The GSE6475 dataset was utilized to identify differentially expressed genes (DEGs) between acne-affected and normal skin samples (each group n=6). A total of 573 DEGs were identified and mapped to the KEGG inflammatory pathway. The hub gene analysis results showed six genes, including CXCL1, STAT1, and PIK3 (adj. P-value < 0.05). These key genes were then used to cross-validate skin grouping with acne lesions and normal skin. The structure of compounds (natural products) in tea leaves (C. sinensis var. assamica) was obtained from the PubChem database, and their activity against target proteins associated with the identified key genes was predicted using the SkelSpheres descriptor and Support Vector Regression method. This quantitative structure–activity relationship (QSAR)-based machine learning approach was selected because it enables high-throughput prediction of inhibitory potential using chemical descriptors and experimentally derived bioactivity data, providing broader predictive power than conventional molecular docking or molecular dynamics, which rely mainly on structural and energetic estimations. The in-silico prediction results showed that compounds such as theobromine, assamsaponin, procyanidin, and caffeine have exhibited good predicted activity (IC₅₀ ranging from 1.125 to 1.320 μM) as potential inhibitors of the PI3K/Akt pathway, which is known to play a role in the pathogenesis of acne.