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All Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva
Noor Aziza
Universitas Islam Sultan Agung
Dentistry

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Antibacterial Effects of Ethanolic Extract of Bidara (Ziziphus mauritiana Lam) Leaf Against Porphyromonas gingivalis Noor Aziza; Islamy Rahma Hutami; Recita Indraswary; Suryono Suryono
Insisiva Dental Journal: Majalah Kedokteran Gigi Insisiva Vol 11, No 2 (2022): November
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/di.v11i2.15222

Abstract

The bidara plant (Ziziphus mauritiana Lam) is widely distributed in various Asian countries. Bidara leaves contain secondary metabolites, the main content of which is flavonoids. As a gram-negative anaerobic bacteria, Porphyromonas gingivalis is one of the normal flora of the oral cavity. However, over quantities of this bacteria can promote chronic periodontitis. This research aims to analyze the bidara leaf ethanolic extract as an inhibitory agent of Porphyromonas gingivalis. This research design is experimental laboratory research with a post-test controlled group of Porphyromonas gingivalis inhibition. A total of 25 samples consisted of 5 groups of ethanol extract of bidara leaves at concentrations of 1%, 3%, 9%, positive control betel leaves, and negative control aquadest. Bacteria incubation was held for 48 hours, and the free bacterial zone was analyzed by the One Way ANOVA test. The results of the analysis showed that there was a significant difference between the control group and the treatment group. This study concludes that the ethanol extract of bidara leaves had a strong inhibitory effect on Porphyromonas gingivalis.
Co-Authors Islamy Rahma Hutami, Islamy Rahma Recita Indraswary Suryono Suryono