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Effectiveness of Helichrysum italicum Essential Oil on Wound Healing Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 10, No 2 (2022): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5324

Abstract

Helichrysum italicum essential oils (EOs) has long been known as a medicinal agent, especially in wound healing. This is inseparable from the chemical compounds contained in it, such as abundant monoterpenes and sesquiterpenes. The purpose of this systematic review is to examine various studies on the effectiveness of H. italicum EOs on wound healing. Research data searches were conducted through Google Scholar, Proquest, Science Direct, SpringerLink, Wiley Online Library, Taylor & Francis Online and PubMed over the last 10 years by following inclusion and exclusion criteria. Obtained as many as 11 studies that match the criteria. Based on the review of these studies, it was found that H. italicum EOs has good wound healing abilities when viewed from various aspects such as its chemical components, biological activity and its effect on injured body tissues. These chemical components vary in type and amount because they are influenced by various aspects. Biological activities such as antioxidant, antimicrobial, and anti-inflammatory effects have also been shown to be contained in this oil because it affects various phases of wound healing, namely hemostasis, inflammation, proliferation and remodeling phases. This is also inseparable from the accuracy of the type of vehicle used.
The Effect of Natural Essential Oil Depigmenting Agent for Alternative Treatment of Melasma Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 11, No 1 (2023): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.6131

Abstract

Melasma, known as a hyperpigmentation disorder, is more common in women of childbearing age with Fitzpatrick IV-VI skin types. Various factors of this disease, namely genetic factors, UV exposure, hormonal, thyroid disease, pregnancy, and drugs. The best treatment for melasma is with 2 – 4% hydroquinone, but because of the side effects, alternative treatments are mostly used for melasma. One of them is with essential oils. Essential oils have been investigated as depigmenting agents because of their anti-tyrosinase potential. In this literature, it is proven that the essential oils of sage (Salvia), hedgenettle / woundwort (Stachys), lavender (Lavandula), tea tree (Melaleuca alternifolia), cinnamon (Cinnamomum), mountain tea (Sideritis), pomelo (Citrus grandis ( L) Osbeck), and kaffir lime (Citrus hystrix DC) are effective against melasma. The purpose of this literature is to discuss the various effects of essential oils that can be used as depigmentation agents in the alternative treatment of melasma.
Effectiveness of Helichrysum italicum Essential Oil on Wound Healing Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 10, No 2 (2022): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5324

Abstract

Helichrysum italicum essential oils (EOs) has long been known as a medicinal agent, especially in wound healing. This is inseparable from the chemical compounds contained in it, such as abundant monoterpenes and sesquiterpenes. The purpose of this systematic review is to examine various studies on the effectiveness of H. italicum EOs on wound healing. Research data searches were conducted through Google Scholar, Proquest, Science Direct, SpringerLink, Wiley Online Library, Taylor & Francis Online and PubMed over the last 10 years by following inclusion and exclusion criteria. Obtained as many as 11 studies that match the criteria. Based on the review of these studies, it was found that H. italicum EOs has good wound healing abilities when viewed from various aspects such as its chemical components, biological activity and its effect on injured body tissues. These chemical components vary in type and amount because they are influenced by various aspects. Biological activities such as antioxidant, antimicrobial, and anti-inflammatory effects have also been shown to be contained in this oil because it affects various phases of wound healing, namely hemostasis, inflammation, proliferation and remodeling phases. This is also inseparable from the accuracy of the type of vehicle used.
The Effect of Natural Essential Oil Depigmenting Agent for Alternative Treatment of Melasma Linda Julianti Wijayadi; Kelvin Kelvin
Journal of Food and Pharmaceutical Sciences Vol 11, No 1 (2023): J.Food.Pharm.Sci
Publisher : Institute for Halal Industry and System (IHIS) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.6131

Abstract

Melasma, known as a hyperpigmentation disorder, is more common in women of childbearing age with Fitzpatrick IV-VI skin types. Various factors of this disease, namely genetic factors, UV exposure, hormonal, thyroid disease, pregnancy, and drugs. The best treatment for melasma is with 2 – 4% hydroquinone, but because of the side effects, alternative treatments are mostly used for melasma. One of them is with essential oils. Essential oils have been investigated as depigmenting agents because of their anti-tyrosinase potential. In this literature, it is proven that the essential oils of sage (Salvia), hedgenettle / woundwort (Stachys), lavender (Lavandula), tea tree (Melaleuca alternifolia), cinnamon (Cinnamomum), mountain tea (Sideritis), pomelo (Citrus grandis ( L) Osbeck), and kaffir lime (Citrus hystrix DC) are effective against melasma. The purpose of this literature is to discuss the various effects of essential oils that can be used as depigmentation agents in the alternative treatment of melasma.