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The Effect of Turmeric Decoctum to the Angiogenic Molecules Expression on Chicken Embryo Sultanah Zahariah; Sri Winarsih; Siti Candra Windu Baktiyani; Bambang Rahardjo; Umi Kalsum
Journal of Tropical Life Science Vol. 7 No. 1 (2017)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.07.01.10

Abstract

Turmeric (Curcuma longa) is widely used as herbal medicine, not an exception by pregnant women. Turmeric consumption by expectant mothers requires standard dose, because of its antiangiogenic effect could be harmful on placentation process and embryonic development. This experiment was undertaken to determine the effect of different concentrations of turmeric decoctum to the expression of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) and Angiopoietin 1 (Ang-1) on the 48-hours-old chicken embryo. In this study, turmeric was extracted using decoction method to mimic the common method as adopted by people. The turmeric decoctum were freeze dried into a powder form and was used in preparing the stock solution for 200 ppm (P1), 300 ppm (P2), and 400 ppm (P3) as experimental treatments. The control group (P0) received 2% DMSO without turmeric decoctum. These were administered on the yolk sack of 16 hours incubation of fertile chicken egg by number of 200 µL. After 48 hours incubation, the expression of VEGFR-2 and Ang-1 on the chicken embryo were counted by ImageJ software. The results revealed that there is no significant effect of turmeric decoctum to the expression of VEGFR-2 and Ang-1. This suggested that turmeric decoctum was safe up to 400 ppm on chicken embryo.
Peningkatan Pengetahuan Kader Kesehatan mengenai Program Persiapan Persalinan dan Pencegahan Komplikasi (P4K) di Kecamatan Gumukmas Sultanah Zahariah
Journal of Health Innovation and Community Services Vol. 1 No. 2 (2022): Journal of Health Innovation and Community Services
Publisher : PPPM Stikes Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/jhics.v1i2.55

Abstract

Background: Maternal mortality rate in the region of East Java has increased in 2020 namely 98,39/100.000 KH. Jember has the highest of maternal mortality rate in the East Java, which is 173,53/100.000 KH. Maternal mortality can occur either during pregnancy, childbirth or the puerperium period. Gumukmas is one of district in Jember which has a percentage of birth assisted by health workers as much as 98,2%, which means that there are still 1,8% of mother who gave birth not assisted by health provider. Kader as part of the community that close to pregnan women are expected to be able yo take a role in the implementation of the Childbirth Planning and Camplications Prevention Program (P4K). The aim of this study is to improve the kader’s ability to provide information to pregnant women about preparation for childbirth in Gumukmas. Method: the method that used is counseling by evaluating the increase of kader’s knowledge through pre and posttest questionnaire.Result: the result was found that 88% of kader have increase of knowledge in childbirtg preparation program and prevention of complication, 12 % have the same knowledge, and there were no participants with decrease of knowledge. This shows that the counseling carried out is quite efficient. Suggestion This result is expected to increase the ability of kader in providing education to pregnant women and families in preparing safety deliveries