Chronic kidney disease is one of the deadliest diseases in the world. It is important to identify chronic kidney disease at an early stage, so that treatment and prevention can be carried out early. This study used linear interpolation method to treat the missing values, resampling using SMOTE method, and several feature selection methods, such as Pearson’s correlation coefficient and Principal component analysis. For the classification methods, Support Vector Machine and Logistic Regression were used to build prediction models for chronic kidney disease based on dataset on UCI Machine Learning. To measure the performance of the model, several test scenarios were tested out so it can be compared to the previous research on the detection of chronic kidney disease, which is used as a benchmark for this study. The best result from the experiment is obtained from the scenario of resampling using SMOTE and feature selection using Principal Component Analysis with averaged accuracy, precision, and f1-score respectively are 98,8%, 100%, dan 98,77%.