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All Journal International Journal of Health Sciences Kunir: Jurnal Farmasi Indonesia (KJFI) Journal of Chemistry Sciences and Education
Farida Fakhrunnisa, Farida
Program Studi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Islam Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Other

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Aktivitas Antibakteri Kombinasi Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Dan Daun Sirih Hijau (Piper Betle L.) Terhadap Bakteri Staphylococcus Aureus Anindya, Yuarinda Melly; Rejeki, Desi Sri; Nurhidayati, Lailiana Garna; Fakhrunnisa, Farida
Journal of Chemistry Sciences and Education Vol 1 No 02 (2024): Journal of Chemistry Sciences and Education
Publisher : PT. Pubsains Nur Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69606/jcse.v1i02.163

Abstract

Wuluh starfruit (Averrhoa bilimbi L.) and green betel (Piper betle L.) leaves are medicinal plants that have antibacterial properties. Medicinal plants can be used as alternative medicine to obtain new compounds as antibacterial. The chemical compounds in wuluh starfruit leaves that have antibacterial properties are flavonoids, saponins and tannins, while green betel leaves have flavonoids, saponins, tannins and essential oils. The study aimed to determine the antibacterial activity of a combination of wuluh starfruit and green betel leaves extract against the growth of Staphylococcus aureus. The experimental research used a diffusion method by disc paper based on the diameter of the inhibition zone or the clear area formed around the paper disc. The extracts were obtained by maceration method using 96% ethanol solvent. The values of the inhibition zone in four concentrations; 5%, 10%, 15%, and 20% were respectively 13 mm, 13.5 mm, 15 mm, and 16 mm. On the other hand, the concentration of 20% had the most effective inhibition zone with a strong category against Staphylococcus aureus.  
Evaluasi Penggunaan Antibiotik di Puskesmas Kabupaten Tegal di Jawa Tengah Dengan Metode ATC/ DDD Fakhrunnisa, Farida
KUNIR: JURNAL FARMASI INDONESIA Vol 2 No 1 (2024): JULI
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v2i1.670

Abstract

Puskesmas merupakan pelayanan kesehatan tingkat pertama yang memiliki pelayanan andalan peresepan dan penggunaan obat. Antibiotik merupakan salah satu obat yang sering diresepkan. Penggunaan yang berlebihan dapat menjadikan resistensi antibiotik. Penelitian ini bertujuan untuk mengevaluasi kuantitas penggunaan antibiotik sebelum dan sesudah dilakukan intervensi edukasi. Penelitian dilakukan di 5 Puskesmas di wilayah Kabupaten Tegal yang memiliki Apoeker, dokter umum dan dokter gigi serta sudah menggunakan Sistem Informasi dan manajemen Puskesmas (SIMPus). Instrumen penelitian mengguna LPLPO periode 1 Juni – 31 Agustus 2018 digunakan sebagai data pre intervensi (P1) dan November 2018 – 31 Januari 2019 untuk post intervensi (P2), Panduan Praktek Klinis Faskes Primer 2024 dan Indeks ATC/DDD Collaborating Centre 2018. Kuantitas penggunaan antibiotik dihitung dalam satuan DDD/1000 KPRJ/hari. Diagnosis terbanyak yang mendapatkan resep antibiotik yaitu Nasopharingitis akut (common cold) dan antibiotik yang paling banyak diresepkan yaitu Amoxicillin, Ciprofloxacin dan Cotrimoxazol. Kuantitas total penggunaan antibiotik pada P1 sebasar 14, 960 DDD / 1000 KPRJ/ hari dan 9, 375 DDD / 1000 KPRJ / hari pada P2. Pemberian intervensi edukasi pada penelitian ini dapat menurunkan kuantitas peresepan antibiotik di Puskesmas secara signifikan (p value : 0,062). Kata Kunci : Evaluasi Penggunaan Obat, Antibiotik, ATC/DDD
Type 2 Diabetes Mellitus Risk Factors Based On An Analytical Epidemiology Approach In Community Health Centers Ibrahim, Ikhsan; Fahamsya, Arifina; Fakhrunnisa, Farida
International Journal of Health Sciences Vol. 3 No. 4 (2025): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v3i4.896

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic disease with increasing prevalence in Indonesia and is a leading cause of morbidity and mortality. According to the 2023 Basic Health Research (Riskesdas), the prevalence of DM in Indonesia has reached 2.3%, with a trend of increasing annually. Community health centers (Puskesmas), as first-level health care facilities, play a crucial role in early detection and control of T2DM risk factors. Objective: This study aims to analyze the risk factors associated with the incidence of Type 2 Diabetes Mellitus based on an analytical epidemiological approach in the working area of Health Center X. Methods: The study design used a case-control study approach with a sample size of 100 respondents (50 cases and 50 controls). Independent variables included age, obesity, physical activity, diet, family history, and smoking habits. Data analysis was performed bivariately using the Chi- Square test and multivariately using multiple logistic regression. Bivariate analysis showed that variables significantly associated with the incidence of Type 2 DM were obesity (p = 0.001), low physical activity (p = 0.003), high-calorie diet (p = 0.002), and family history of DM (p = 0.004). Logistic regression results showed that obesity was the most dominant risk factor with Odds Ratio (OR) = 5.6 (95% CI: 2.1–14.9). Conclusion: Obesity, low physical activity, high-calorie diet, and family history of DM have been shown to be significant risk factors for the occurrence of Type 2 Diabetes Mellitus. Preventive efforts can be carried out through balanced nutrition education, promotion of physical activity, and early detection in individuals with high-risk factors.
Co-Authors Anindya, Yuarinda Melly Desi Sri Rejeki Fahamsya, Arifina Ikhsan Ibrahim Nurhidayati, Lailiana Garna