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All Journal Majalah Sainstekes Junior Medical Journal
Etty Widayanti Etty Widayanti
Department of Anatomy, Faculty of Medicine, Universitas YARSI, Jakarta 10510, Indonesia
Religion Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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Journal : Junior Medical Journal

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Literature Review : The Effects of Antioxidant Saponins in Herbal Plants on Testicular Histology of Rats with Diabetes Mellitus and The Review of Islamic Perspective Jean Kharismatik Persada; Etty Widayanti; Aan Royhan
Junior Medical Journal Vol 1, No 8 (2023)
Publisher : Junior Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v1i8.3313

Abstract

Introduction: Diabetes mellitus is a metabolic disorder. Diabetes mellitus can cause a decrease in sperm count, sperm motility, testosterone hormone, erectile ability, libido and testicular weight. Antidiabetic drugs consumed long-term can cause side effects; therefore, alternative treatment is needed using herbal medicinal plants. Saponins in plants are a complex class of complex natural compounds with a large molecular mass, namely steroid or triterpenoid aglycones with one or more sugar/glycoside chains. Saponins function as antioxidants. This study aims to determine the effect of saponins as one of the antioxidants on the testicular organs of rats (Rattus norvegicus) Wistar strain-induced Streptozotocin. Methods: This study used the Literature Review method with a narrative literature review type. The data collection technique uses a search for several research databases through Google Scholar and Mendeley. This research has four journals that will review. Results: The results showed that herbal plants have bioactive compounds such as flavonoids, alkaloids, terpenoids, tannins, and saponins that have antidiabetic effects with different mechanisms in reducing blood glucose levels repairing damage to testicular tissue of diabetes mellitus rats. Conclusion: Antioxidant saponins in herbal plants influence improving and supporting the repair of testicular histology damage in diabetic cases. Allah SWT grows a wide variety of plants that have enormous benefits for humans, including food and medicine, because Allah SWT created various kinds of plants with multiple uses.
Literature Review : Effect of Herbal Plant Extracts Containing Tannins on Histopathological Kidney of Diabetic Rats riza, salim; Etty Widayanti; Aan Royhan
Junior Medical Journal Vol. 2 No. 3 (2023): November 2023
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v2i3.3317

Abstract

Hyperglycemia is a disorder of carbohydrate metabolism characterized by high blood glucose levels. Hyperglycemic treatment is usually done by administering oral hyperglycemic drugs. Therapy using drugs, either in the form of oral anti-diabetic drugs, insulin therapy, or a combination of both. Herbal medicine can be an alternative treatment in the treatment of hyperglycemia. Various types of extracts from various parts of several medicinal plants have been tested for hyperglycemic activity, one of which is due to the content of tannin compounds. The purpose of this study was to determine the effect of herbal plant extracts containing tannins on the histopathological of the kidneys of diabetic rats. The research method uses the Literature Review method with secondary data collection from scientific research articles from 2019-2023. Search data using the online Google Scholar database using key words such as tannins, diabetes, histopathology, kidney and rats. Articles are then evaluated based on the title and abstract. From the 5 results of this Literature Review, all literature states that there is an effect of herbal plant extracts containing tannins on the histopathological  of the kidneys of diabetic rats.
Pengetahuan dan Sikap Mengenai Perlindungan dari Paparan Sinar Matahari pada Pekerja Lapangan di Kelurahan Tugu Utara, Kecamatan Koja, Jakarta Utara Syifa Aini Fiqri; Mirfat; Etty Widayanti
Junior Medical Journal Vol. 3 No. 4 (2025): Juni 2025
Publisher : Fakultas Kedokteran Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jmj.v3i4.4886

Abstract

Pendahuluan: Paparan sinar matahari yang berlebihan dapat berdampak negatif pada kesehatan kulit, termasuk risiko kanker kulit, penuaan dini, dan kerusakan sistem kekebalan tubuh. Penelitian ini bertujuan untuk mengetahui bagaimana pengetahuan dan sikap mengenai perlindungan dari paparan sinar matahari pada pekerja lapangan di Kelurahan Tugu Utara, Kecamatan Koja, Jakarta Utara. Metodologi: Penelitian analitik dengan rancangan cross-sectional menggunakan total sampling. Data yang digunakan dalam penelitian ini adalah data primer yang berasal dari hasil survei kuesioner yang diisi oleh responden yang bersedia dan mengisi kuesioner secara lengkap. Analisis data menggunakan analisis univariat dan bivariat dengan Software Statistical Package For Social Science (SPSS) versi 29.0., uji fisher exact. Hasil: Jumlah responden dalam penelitian ini sebanyak 107 pekerja lapangan, 71 responden (66.4%) memiliki pengetahuan yang kurang mengenai perlindungan dari paparan sinar matahari sedangkan responden yang memiliki sikap buruk mengenai perlindungan dari paparan sinar matahari sebanyak 81 responden (75.7%). Pengetahuan (p=0,001) dan sikap (p=0,002) mengenai perlindungan dari paparan sinar matahari antara pekerja lapangan laki-laki dan perempuan di wilayah penelitian memiliki perbedaan yang signifikan. Simpulan: Hasil penelitian menunjukkan bahwa pengetahuan kurang dan sikap buruk mengenai perlindungan dari paparan sinar matahari pada pekerja lapangan, serta terdapat perbedaan pengetahuan dan sikap mengenai perlindungan dari paparan sinar matahari antara pekerja lapangan laki-laki dan perempuan di wilayah penelitian (p<0,05).
Co-Authors Aan Royhan Abyan Fajri Ramadhan Ahmad Rafi Faiq Endang Purwaningsih Jean Kharismatik Persada Mirfat Mirfat Mirfat riza, salim Syifa Aini Fiqri Yenni Zulhamidah