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All Journal JBIO: jurnal biosains (the journal of biosciences) Medika Respati : Jurnal Ilmiah Kesehatan
Winda Maulinasari Nasution
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PENGARUH PEMAKAIAN KONTRASEPSI HORMONAL DAN RIWAYAT KELUARGA TERHADAP KEJADIAN KANKER PAYUDARA DI RSUD Dr. PIRNGADI MEDAN TAHUN 2017 Winda Maulinasari Nasution; Asfriyati Asfriyati; Fazidah Aguslina Siregar
Medika Respati : Jurnal Ilmiah Kesehatan Vol 13, No 2 (2018)
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (415.574 KB) | DOI: 10.35842/mr.v13i2.156

Abstract

Kanker payudara merupakan dampak kesehatan reproduksi yang menyebabkan kematian utama pada wanita. Di Indonesia kejadian kanker payudara menduduki peringkat kedua setelah kanker serviks. Paparan estrogen yang tinggi merupakan salah satu faktor utama yang diduga berperan dalam proses peningkatan kejadian kanker payudara. Tujuan penelitian untuk mengetahui pengaruh pemakaian kontrasepsi hormonal dan riwayat keluarga terhadap kejadian kanker payudara. Jenis penelitian kuantitatif dengan desain kasus kontrol. Sampel 48 orang kasus adalah penderita kanker payudara dan 48 orang kontrol adalah bukan penderita kanker payudara. Hasil analisis menggunakan uji regresi logistik sederhana menunjukkan bahwa pemakaian kontrasepsi hormonal OR 8,169 (95%CI (3,266-20,431) dan riwayat kanker payudara pada keluarga OR 9,056 (95%CI 3,586-22,871)  mempunyai pengaruh yang signifikan terhadap kejadian kanker payudara. Diharapkan kepada wanita yang mempunyai riwayat kanker payudara pada keluarga sebaiknya tidak menggunakan kontrasepsi hormonal dalam jangka waktu yang lama. Karena dapat mengacaukan keseimbangan hormon estrogen yang mengakibatkan perubahan sel yang normal menjadi abnormal dalam tubuh.Kata Kunci : Kanker Payudara, Kontrasepsi Hormonal, Riwayat Keluarga
The Effect of Date Fruit (Phoenix dactylifera L.) Consumption on Autonomic Nerve Function and Hot Flash Manifestations in Menopausal Women Winda Maulinasari Nasution; Siti Maryam Hasibuan; Lanny Apriani
JURNAL BIOSAINS Vol. 12 No. 1 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/mymr1g24

Abstract

Menopause is a natural phase in a woman’s life marked by decreased estrogen levels and symptoms such as hot flashes, which are linked to autonomic nervous system dysfunction. Hot flashes cause sudden heat sensations, sweating, flushing, and palpitations that can disrupt daily life. Date fruit is rich in antioxidants and phytoestrogens, making it a potential non-hormonal alternative to alleviate menopausal symptoms. This study aimed to analyze the effect of date fruit consumption on autonomic nerve function and hot flash manifestations in menopausal women. A quasi-experimental pretest–posttest control group design was used, involving menopausal women aged 45–60 years experiencing hot flashes at Midwife Hj. Dewi Sesmera’s Clinic, Medan City, North Sumatra. Participants were selected using purposive sampling. The intervention group consumed 50 grams of date fruit daily for eight weeks. Data were collected through questionnaires, interviews, and documentation. Autonomic nerve function was measured using the COMPASS-31 (Composite Autonomic Symptom Score-31), and hot flash frequency and intensity were assessed with the Menopause Rating Scale (MRS). Statistical analysis employed a paired t-test (p < 0.05) using SPSS version 24. Results showed that while improvement in autonomic nerve function was not statistically significant, the frequency and intensity of hot flashes significantly decreased in the intervention group.
Co-Authors Asfriyati ,MKes Fazidah Aguslina Siregar, Fazidah Aguslina Lanny Apriani Siti Maryam Hasibuan