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All Journal Jurnal Pendidikan dan Konseling Jurnal Pembelajaran dan Biologi Nukleus
Saarah Hamidah Asmara Indratno
Universitas Singaperbangsa Karawang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Other

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Artikel Review: Analisis Ekstraksi dan Identifikasi Senyawa Saponin pada Tumbuhan Mahkota Dewa (Phaleria macrocarpa) Saarah Hamidah Asmara Indratno; Priscinya Christiana Debora; Nur Komala Fitri; Tiwi Ambarati; Aliya Azkia Zahra; Vriezka Mierza
Jurnal Pendidikan dan Konseling (JPDK) Vol. 5 No. 1 (2023): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jpdk.v5i1.10948

Abstract

Mahkota dewa (Phaleria macrocarpa) adalah salah satu tanaman obat yang sering digunakan secara empiris oleh masyarakat di Indonesia karena kandungan metabolit sekunder didalamnya, salah satu senyawa tersebut adalah saponin. Metode yang dilakukan untuk menyusun artikel ini yaitu dengan studi literatur dari beberapa jurnal terakreditasi yang terbit selama sepuluh tahun terakhir. Pengujian kandungan senyawa saponin pada mahkota dewa (Phaleria macrocarpa) dilakukan dengan uji busa, dimana hasil positifnya menunjukan adanya busa stabil dengan tinggi 1-10 cm, yang pada saat ditambahkan HCl 2 N sebanyak 1 tetes busa tersebut akan tetap bertahan, sedangkan pada pengujian dengan menggunakan UV-Vis akan memberikan bercak orange kecoklatan setelah disemprotkan reagen Lieberman-Bourchat dan akan ada bercak pada sinar UV 254 nm dan sinar UV 366 nm. Lalu pada saponin steroid akan memberikan cincin hijau pada pengujian warna.
Genetic Studies On The GHSR and IGF1R and Their Relationship With Stunting: A Systematic Literature Review Saarah Hamidah Asmara Indratno; Jekmal Malau; Ahsanal Kasasiah
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 10, No 2: Jurnal Pembelajaran Dan Biologi Nukleus July 2024
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v10i2.5731

Abstract

Stunting, also known as short stature, is a condition that occurs in children where children grow too short for their age. It can be influenced by several external and internal factors. This study explored various databases including Pubmed, Science Direct, Sage Journal, Springer Link, with keywords: "stunting OR short stature AND GHSR AND IGF1R AND genetic". There are 114 articles that match the PICOTS elements to be further reviewed using the PRISMA diagram. In this review article, 10 research articles published in 2011-2024 were used as sources of information. This review article discusses that internal factors of stunting can be caused by genetic factors influenced by growth genes, one of which is GHSR and IGF1R. Whole genome sequencing revealed potential genes involved in the growth pathway that showed an association between genetic variation in GHSR and IGF with the risk of the body's production or response to growth hormone that causes delayed child growth. The evidence highlights the possibility that these putative genetic markers could offer more effective treatment by focusing on the pathophysiology associated with development stunting. Due to lack of genetic studies on stunting genes carried out in Asian nations, genetic testing has not been used in clinical practice as a routine evaluation in the current national implementation, especially in Indonesia
Co-Authors Ahsanal Kasasiah Aliya Azkia Zahra Jekmal Malau Nur Komala Fitri Priscinya Christiana Debora Tiwi Ambarati Vriezka Mierza