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All Journal Medical Scope Journal (MSJ)
Siemona L. E. Berhimpon
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Nursing Public Health

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Description of Leucocyte Differential Count in Pregnant Women with COVID-19 Nabila Alifiah; Siemona L. E. Berhimpon; Glady I. Rambert
Medical Scope Journal Vol. 3 No. 2 (2022): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v3i2.37841

Abstract

Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a high rate of transmission. Pregnant women are at high risk of infection due to the changes in their physiological and immune systems. This study aimed to determine the leukocyte differential count leukocyte in pregnant women with COVID-19. This was a descriptive study with a retrospective approach, using secondary data of the patients’ medical records during the periode of July-August 2021 at Prof. Dr. R. D. Kandou Hospital, Manado. The results showed that of 57 pregnant women with COVID-19, 92% had normal leukocyte differential count, 100% had normal basophil and eosinophil counts, 12% had neutrophilia, 23% had lymphopenia, and 95% had normal monocyte counts. In conclusion, in pregnant women with COVID-19 at Prof. Dr. R. D. Kandou Hospital, the most common abnormalities in leucocyte differential count are lymphopenia and neutrophiliaKeywords: pregnant women; COVID-19; leukocyte differential count  Abstrak: Coronavirus disease 2019 (COVID-19) yang disebabkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mempunyai tingkat penularan yang sangat tinggi. Wanita hamil berisiko tinggi terinfeksi COVID-19 karena adanya perubahan fisiologik dan sistem imun. Penelitian ini bertujuan untuk mengetahui gambaran hitung jenis leukosit pada wanita hamil dengan COVID-19. Jenis penelitian yang digunakan ialah deskriptif retrospektif dengan menggunakan data sekunder rekam medik periode Juli-Agustus 2021 di RSUP Prof. Dr. R. D. Kandou. Hasil penelitian memperlihatkan bahwa dari 57 wanita hamil terkonfirmasi COVID-19, terdapat 92% dengan nilai hitung leukosit normal, 12% mengalami neutrofilia, 23% mengalami limfopenia, 95% memiliki nilai hitung monosit normal, dan 100% memiliki nilai hitung basofil dan eosinofil normal. Simpulan penelitian ini ialah kelainan hitung jenis leukosit yang paling sering ditemukan pada wanita hamil terkonfirmasi COVID-19 di RSUP Prof. Dr. R. D. Kandou ialah neutrofilia dan limfopenia.Kata kunci: wanita hamil; COVID-19; hitung jenis leukosit
Hubungan Obesitas dengan Tingkat Keparahan COVID-19 Shally G. C. P. Lahagina; Mayer F. Wowor; Siemona L. E. Berhimpon
Medical Scope Journal Vol. 5 No. 1 (2023): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v5i1.45130

Abstract

Abstract: Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by infection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. Obesity is one of the risk factors that might increase the severity of COVID-19 due to anatomical and physiological changes in the body. Previous studies have shown high mortality and morbidity rates in obese patients with COVID-19. This study aimed to evaluate the association between obesity and the severity of COVID-19. This was a literature review study. The results obtained 17 articles concluding that there was an association between obesity and the severity of the disease, however, one article concluded no association between them. The reported severity criteria ranged from severe to critical ill. In conclusion, obese patients with had higher risk to suffer form more severe COVID-19. The outcomes of obese patients with COVID-19 are hospitalization, admission at Intensive Care Unit, intubation, and death. Keywords: COVID-19; obesity; disease severity   Abstrak: Coronavirus Disease 2019 (COVID-19) merupakan penyakit pernapasan akut yang disebabkan oleh infeksi virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Obesitas merupakan salah satu faktor risiko yang dapat meningkatkan keparahan COVID-19 terkait adanya perubahan anatomi dan fisiologis tubuh. Hasil penelitian sebelumnya menunjukkan angka mortalitas dan morbiditas yang tinggi pada pasien obesitas dengan COVID-19. Penelitian ini bertujuan untuk mengetahui lebih lanjut mengenai hubungan obesitas dengan tingkat keparahan penyakit pada COVID-19. Jenis penelitian ialah suatu literature review. Hasil penelitian mendapatkan 17 artikel yang menyimpulkan adanya hubungan obesitas dengan tingkat keparahan penyakit pada COVID-19 dan satu artikel menyimpulkan tidak terdapat hubungan obesitas dengan tingkat keparahan penyakit pada COVID-19. Kriteria tingkat keparahan yang dilaporkan mulai dari berat sampai kritis. Simpulan penelitian ini ialah pasien obesitas dengan COVID-19 berisiko lebih tinggi untuk mengalami keparahan penyakit. Luaran pasien dengan obesitas yaitu dirawat inap, menerima perawatan di Intensive Care Unit, diintubasi, dan kematian. Kata kunci: COVID-19; obesitas; tingkat keparahan penyakit
Co-Authors Glady I. Rambert Mayer F. Wowor Nabila Alifiah Shally G. C. P. Lahagina