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POTENSI GEL HANDSANITIZER EKSTRAK DAUN KITOLOD (Isotoma longiflora L.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus Septiana Laksmi Ramayani
Jurnal Jamu Kusuma Vol. 2 No. 1 (2022): JURNAL JAMU KUSUMA
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.398 KB) | DOI: 10.37341/jurnaljamukusuma.v2i1.26

Abstract

Staphylococcus aureus is a Gram positive and commensal bacteria that colonizes 30% of healthy individuals in various parts of the body. Kitolod (Isotoma longiflora L )leaf extract has antibacterial activity against Staphylococcus aureus bacteria and may be developed into hand sanitizer gel preparations. The purpose of this study was to determine the antibacterial activity of the hand sanitizer gel preparation of kitolod leaf extract. Kitolod leaf extract was macerated with 96% ethanol and then formulated into a hand sanitizer gel preparation. Antibacterial activity was carried out using the Kirby Bauer method using a negative control of 10% DMSO and a gel base, while the positive control was a gel hand sanitizer on the market. The results showed that the negative control did not show antibacterial activity, while the positive control, kitolod leaf extract and hand sanitizer gel preparations of kitolod leaf extract gave a clear zone indicating the presence of antibacterial activity against Staphylococcus aureus bacteria. The antibacterial activity of the kitolod leaf extract hand sanitizer gel was classified in the strong category
Pengaruh Ukuran Partikel dan Lama Penyulingan Terhadap Jumlah Rendemen Minyak Atsiri Serbuk Temulawak (Curcuma xanthorrhiza) Septiana Laksmi Ramayani; Chatarina Hartiningty Ratna Meilyanawati
Jurnal Kesehatan Farmasi Vol 4, No 2 (2022)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (659.245 KB) | DOI: 10.36086/jpharm.v4i2.1450

Abstract

Background: Java tumeric (Curcuma xanthorrhiza) is a medicinal plant native to Indonesia which has been empirically proven to be efficacious for health to cure various types of diseases. One of the compounds in Java tumeric is essential oil. The purpose of this study was to determine the effect of particle size and distillation time on the yield of Java tumeric essential oil. Method: The extraction method used is hydrodistillation. The variables in this study were particle size (425µm and 250µm) and distillation time (3.4 and 5 hours). The data obtained were analyzed using Kruskal Wallis and followed by Mann Whitney. Results: The results showed that a particle size of 250µm resulted in a greater yield of essential oils than a particle size of 425µm. Distillation time of 5 hours produces a greater yield of essential oils than distillation time of 4 hours or 3 hours. The smaller the particle size and the longer the distillation time, the greater the yield of essential oil produced. Conclusion: Particle size and distillation time affect the yield of java tumeric essential oil.