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All Journal Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) JURNAL JAMU KUSUMA Jurnal Kesehatan Farmasi Jurnal Kesehatan dr. Soebandi
Septiana Laksmi Ramayani
Poltekkes Kemenkes Surakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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POTENSI GEL HANDSANITIZER EKSTRAK DAUN KITOLOD (Isotoma longiflora L.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus Septiana Laksmi Ramayani
Jurnal Jamu Kusuma Vol. 2 No. 1 (2022): JURNAL JAMU KUSUMA
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (269.398 KB) | DOI: 10.37341/jurnaljamukusuma.v2i1.26

Abstract

Staphylococcus aureus is a Gram positive and commensal bacteria that colonizes 30% of healthy individuals in various parts of the body. Kitolod (Isotoma longiflora L )leaf extract has antibacterial activity against Staphylococcus aureus bacteria and may be developed into hand sanitizer gel preparations. The purpose of this study was to determine the antibacterial activity of the hand sanitizer gel preparation of kitolod leaf extract. Kitolod leaf extract was macerated with 96% ethanol and then formulated into a hand sanitizer gel preparation. Antibacterial activity was carried out using the Kirby Bauer method using a negative control of 10% DMSO and a gel base, while the positive control was a gel hand sanitizer on the market. The results showed that the negative control did not show antibacterial activity, while the positive control, kitolod leaf extract and hand sanitizer gel preparations of kitolod leaf extract gave a clear zone indicating the presence of antibacterial activity against Staphylococcus aureus bacteria. The antibacterial activity of the kitolod leaf extract hand sanitizer gel was classified in the strong category
Pengaruh Ukuran Partikel dan Lama Penyulingan Terhadap Jumlah Rendemen Minyak Atsiri Serbuk Temulawak (Curcuma xanthorrhiza) Septiana Laksmi Ramayani; Chatarina Hartiningty Ratna Meilyanawati
Jurnal Kesehatan Farmasi Vol 4, No 2 (2022)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (659.245 KB) | DOI: 10.36086/jpharm.v4i2.1450

Abstract

Background: Java tumeric (Curcuma xanthorrhiza) is a medicinal plant native to Indonesia which has been empirically proven to be efficacious for health to cure various types of diseases. One of the compounds in Java tumeric is essential oil. The purpose of this study was to determine the effect of particle size and distillation time on the yield of Java tumeric essential oil. Method: The extraction method used is hydrodistillation. The variables in this study were particle size (425µm and 250µm) and distillation time (3.4 and 5 hours). The data obtained were analyzed using Kruskal Wallis and followed by Mann Whitney. Results: The results showed that a particle size of 250µm resulted in a greater yield of essential oils than a particle size of 425µm. Distillation time of 5 hours produces a greater yield of essential oils than distillation time of 4 hours or 3 hours. The smaller the particle size and the longer the distillation time, the greater the yield of essential oil produced. Conclusion: Particle size and distillation time affect the yield of java tumeric essential oil.
The Effect of Kitolod (Isotoma Longiflora) Leaf Extract Concentration in Gel Formula on Total Phenolic and Flavonoid Levels Septiana Laksmi Ramayani; Dania Fauzita Rarasati; Yuliya Rizky Widyastuti
Jurnal Kesehatan dr. Soebandi Vol 12 No 1 (2024): Jurnal Kesehatan dr. Soebandi
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v12i1.573

Abstract

Belonging to the Campanulaceae family, Kitolod (Isotoma longiflora) possesses antioxidant properties crucial for wound healing; presenting a case for its formulation into a gel and investigating the total phenolic and flavonoid content of kitolod leaf extract when in gel form is essential to understand its capabilities as an anti-inflammatory and wound-healing gel, as well as to examine the possible correlation between the extract's concentration and its phenolic and flavonoid content. This study assessed how different concentrations of kitolod leaf extract affect the total phenolic and flavonoid levels in a gel formulation. Using 96% ethanol, kitolod leaves were macerated. The gel formulations contained varying concentrations of kitolod leaf extract: F1(5%), F2(10%), and F3(20%). The presence of phenols and flavonoids was confirmed through qualitative tests using FeCl3 1% for phenols and the Shinoda test for flavonoids. The findings confirmed that the total levels of phenolics and flavonoids increased with the concentration of kitolod leaf extract in the gel. SPSS analysis showed a strong correlation between extract concentration in the gel and the amounts of total phenolics and flavonoids, highlighting a positive relationship between these two chemical compounds since they are in the same category.
EVALUATION OF THE PHYSICAL, PHYTOCHEMICAL, AND HEDONIC QUALITY OF HERBAL POWDERED BEVERAGES COMBINING ELEPHANT GINGER (Zingiber officinale Roscoe), GARLIC (Allium sativum L.), AND CITRONELLA (Cymbopogon nardus L. Rendle) Nur Atikah; Septiana Laksmi Ramayani; Melinda Eka Pratiwi
Jurnal Jamu Kusuma Vol. 4 No. 2 (2024): JURNAL JAMU KUSUMA
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jurnaljamukusuma.v4i2.111

Abstract

Hypertension can be managed using traditional medicinal plants such as elephant ginger, garlic, and citronella, which can be processed into instant powdered beverage formulations. This study evaluates the physical quality, phytochemical properties, and hedonic characteristics of powdered formulations combining these three ingredients. The study employed an observational method. Instant powdered formulations were prepared using the crystallization method, with three variations of white sugar to palm sugar ratios: 2:0 (F1), 1.5:0.5 (F2), and 1:1 (F3). A univariate analysis was conducted to evaluate the physical qualities of the powders, including organoleptic properties, pH, moisture content, tapping density, angle of repose, and dissolution time, as well as to report the results of phytochemical screening and hedonic evaluation (taste, aroma, and color). The results revealed variations in the physical properties of the three formulations. The pH values were 5.91, 5.90, and 5.74 for F1, F2, and F3, respectively. Moisture content was recorded at 1%, 1.33%, and 3.33%, while tapping density was 8.33%, 11%, and 11.33%. Flow times were 10.57 seconds, 10.68 seconds, and 11.34 seconds, while the angles of repose were measured at 32.37°, 26.47°, and 37.81°. Dissolution times were recorded as 15.3 seconds, 17.17 seconds, and 18.15 seconds. Formula 1 (F1) demonstrated the best physical quality based on established standards among the formulations. Phytochemical screening for all three formulations (F1–F3) indicated the presence of flavonoids and saponins, while tests for alkaloids and terpenoids yielded negative results. The hedonic evaluation, conducted using F1 due to its superior physical quality, showed that out of 31 respondents, 17 rated it as "like," 8 as "neutral," and 6 as "very like." In conclusion, although the flow time parameter did not meet the standard requirement, F1 exhibited the best physical quality, contained beneficial phytochemicals (flavonoids and saponins), and was well-received by the majority of respondents in terms of taste, aroma, and color.
Penyuluhan Hipertensi Sebagai Upaya Promotif dan Preventif di Desa Danguran RW 13 Kecamatan Klaten Selatan Septiana Laksmi Ramayani; Aditya Bagus Setiawan; Melinda Tri Yuliani; Lissa Mary Agatha Sari; Cindy Egi Meylani Putri; Arlintang Dian Maharani
Jurnal Dimas Vol 7 No 1 (2025): Jurnal Pengabdian Kepada Masyarakat
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v7i1.104

Abstract

Hypertension is one of the health problems that is increasingly rising worldwide and is often referred to as a "silent killer."Hypertension often does not show clear symptoms, so many individuals are unaware of it, making it one of the causes of non-communicable diseases that can lead to serious complications such as stroke, heart disease, and kidney failure.Hypertension is defined as an increase in systolic blood pressure greater than or equal to 140 mmHg, and an increase in diastolic pressure greater than or equal to 90 mmHg.Promotive and preventive efforts for hypertension can be carried out through health education and health screening.This counseling can increase knowledge about hypertension, including risk factors, symptoms, and prevention methods.With the increase in knowledge, it is hoped that the community can be more proactive in maintaining their health and taking appropriate preventive measures.Community service activities were conducted in Danguran Village RW 13, Klaten Selatan District, Klaten Regency, Central Java.The activity was attended by 22 community members.The activity began with a pretest – distribution of material leaflets – presentation of material and demonstration of making traditional concoctions to lower blood pressure – posttest.Based on the community service activities conducted, there was an increase in the community's understanding of hypertension as a promotional and preventive effort.Out of the 20 questions given, 19 questions showed an increase in understanding and 1 question showed no change.Based on the level of understanding, there was an increase in the good category from the pretest and posttest scores by 40, resulting in an average increase in understanding of 40.91%.
Pelatihan Pembuatan Sediaan Gummy candies Sari Umbi Bit (Beta vulgaris L.) sebagai Suplemen Anemia bagi Ibu Hamil dan Anak-anak: Pelatihan Pembuatan Sediaan Gummy Candies Sari Umbi Bit (Beta vulgaris L) Sebagai Suplemen Anemia Bagi Ibu Hamil dan Anak-anak Septiana Laksmi Ramayani; Muhammad Syaifuddin
Jurnal Dimas Vol 8 No 2 (2026): Jurnal Pengabdian Kepada Masyarakat
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v8i2.159

Abstract

Anemia pada ibu hamil merupakan salah satu faktor risiko utama terjadinya Intrauterine Growth Restriction (IUGR) dan Berat Badan Lahir Rendah (BBLR), yang menjadi pemicu tingginya prevalensi Stunting. Data di Kecamatan Bayat, Kabupaten Klaten menunjukkan terdapat 160 ibu hamil dan 52 kasus Stunting, yang memerlukan intervensi gizi. Meskipun program pemberian Tablet Tambah Darah (TTD) telah dijalankan, rendahnya kepatuhan akibat efek samping klinis masih menjadi hambatan utama. Kegiatan pengabdian masyarakat ini bertujuan untuk memberikan solusi melalui diversifikasi pangan berupa pemanfaatan umbi bit (Beta vulgaris) sebagai sumber zat besi alami dalam bentuk sediaan gummy candies. Metode pelaksanaan kegiatan ini meliputi edukasi dengan media brosur dan pelatihan teknis produksi yang melibatkan kader kesehatan, ibu hamil, serta ibu balita di Desa Jarum. Tahapan kegiatan terdiri dari pre-test, penyampaian materi, demonstrasi pembuatan produk, dan post-test. Data pretest dan postest dilakukan uji wilcoxon signed rank test untuk melihat pengaruh pemberian pelatihan pada peserta. Sediaan gummy candies dipilih karena memiliki akseptabilitas yang lebih tinggi dibandingkan suplemen konvensional, terutama bagi yang memiliki sensitivitas terhadap rasa. Melalui pelatihan ini, masyarakat diharapkan mampu memproduksi suplemen secara mandiri sehingga dapat meningkatkan kadar hemoglobin secara signifikan. Pelatihan ini diharapkan berkontribusi langsung pada penurunan angka kejadian anemia dan percepatan penurunan prevalensi Stunting secara berkelanjutan.
Co-Authors Aditya Bagus Setiawan Arlintang Dian Maharani Chatarina Hartiningty Ratna Meilyanawati Cindy Egi Meylani Putri Dania Fauzita Rarasati Lissa Mary Agatha Sari Melinda Eka Pratiwi Melinda Tri Yuliani Muhammad Syaifuddin Nur Atikah Yuliya Rizky Widyastuti