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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Islamic Medicine Science Midwifery
Salsabila Ariefani
Universitas Islam Negeri Sulthan Thaha Saifuddin Jambi, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Journal : journal of islamic medicine

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Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker in Cervical Cancer: A Literature Review of Current Evidence Ariefani, Salsabila; Rahmadhanita, Putri; Finalita, Floera
Journal of Islamic Medicine Vol 10, No 1 (2026): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v10i1.41541

Abstract

Background: The neutrophil-to-lymphocyte ratio (NLR) is a simple systemic inflammatory marker that reflects the balance between pro-tumor inflammation and anti-tumor immunity. Previous studies have shown that a high pre-treatment NLR is associated with poor survival outcomes and advanced clinical stage in cervical cancer. Objective: This review aims to evaluate the prognostic role of NLR and its impact on patient survival. Methods: A literature search was conducted for studies published between 2021-2026 using the PubMed/ MEDLINE database with predefined inclusion and exclusion criteria. A total of eight relevant articles were included in this review. Results: The included studies consistently demonstrated that a high pre-treatment NLR is an independent predictor of poor survival in patients with cervical cancer. Conclusion: NLR appears to be a promising prognostic biomarker for cervical cancer; however, the lack of standardized cut-off values limits its current clinical application.
Co-Authors Eko Fuji Ariyanto Eko Fuji Ariyanto Finalita, Floera Putri Rahmadhanita Yohana Azhar Yohana Azhar