Journal of Islamic Medicine
Vol 10, No 1 (2026): Journal of Islamic Medicine

Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker in Cervical Cancer: A Literature Review of Current Evidence

Salsabila Ariefani (UIN Sulthan Thaha Saifuddin Jambi)
Putri Rahmadhanita (UIN Sulthan Thaha Saifuddin Jambi)
Floera Finalita (UIN Sulthan Thaha Saifuddin Jambi)



Article Info

Publish Date
01 Apr 2026

Abstract

Background: The neutrophil-to-lymphocyte ratio (NLR) is a simple systemic inflammatory marker that reflects the balance between pro-tumor inflammation and anti-tumor immunity. Previous studies have shown that a high pre-treatment NLR is associated with poor survival outcomes and advanced clinical stage in cervical cancer. Objective: This review aims to evaluate the prognostic role of NLR and its impact on patient survival. Methods: A literature search was conducted for studies published between 2021-2026 using the PubMed/ MEDLINE database with predefined inclusion and exclusion criteria. A total of eight relevant articles were included in this review. Results: The included studies consistently demonstrated that a high pre-treatment NLR is an independent predictor of poor survival in patients with cervical cancer. Conclusion: NLR appears to be a promising prognostic biomarker for cervical cancer; however, the lack of standardized cut-off values limits its current clinical application.

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Journal Info

Abbrev

jim

Publisher

Subject

Medicine & Pharmacology

Description

Journal of Islamic Medicine is a medical journal published twice a year in March and September by the School of Medicine, Faculty of Medicine and Medical Sciences, Universitas Islam Negeri Maulana Malik Ibrahim ...