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All Journal Medula Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Marcella Dena Fernanda
Universitas Lampung
Dentistry Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Polusi Udara dan Permasalahan terhadap Kulit Marcella Dena Fernanda; Hendra Tarigan Sibero; Hanna Mutiara
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.590

Abstract

Pollution has been shown to increasingly play a role in several common ailments, and the effects on the skin are no exception. Indoor and outdoor pollutants are widely distributed in urban and rural environments. WHO defines air pollution as contamination of the outdoor (ambient) and indoor (household) environment by any chemical, physical or biological agent that alters the natural characteristics of the atmosphere. Inhaled or ingested pollutants can be distributed throughout the body through the systemic circulation, making the exposed air a target for contaminants in the superficial and deep layers of the skin. The mechanisms by which pollutants may interact with human skin may differ based on each agent and its specific characteristics. Basic and clinical studies have provided growing evidence of the interaction of pollutants with the skin. Pollutants can activate skin metabolic and inflammatory pathways and induce oxidative stress by lowering antioxidant levels in particular. The skin is also a target for another known source of oxidative stress, namely UV radiation. The interaction of pollutants with UV light or the human skin microbiota requires further clinical investigation to evaluate their specific impact on skin health. Both outdoor and indoor pollution were found to increase signs of skin aging such as facial lentigines and wrinkles. Living in a polluted environment can also reduce skin moisture, increase the rate of sebum excretion and possibly worsen symptoms of chronic inflammatory skin diseases in both children and adults. Home location, type of work and diet all lead to internal and external exposure to a variety of pollutants, with clinical consequences that can accumulate or synergize. Pollutants are only one component of exposure which means that both internal and external factors must be considered when establishing pollution protection measures, which necessitates the development of standard methods for their evaluation. This literature review provides an overview of how pollutants affect the health of the skin.
Holistic Management of A Female Patient with Diabetic Neuropathy and Osteoarthritis through Family Medicine Approach Marcella Dena Fernanda; Diana Mayasari
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 12 No. 1 (2025): Jurnal Kesehatan dan Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jka.v12i1.pp363-375

Abstract

Diabetic neuropathy is the most common complication found in diabetes patients, with a lifetime prevalence of over 50% among those with diabetes. The World Health Organization (WHO) estimates that approximately 528 million people worldwide suffer from osteoarthritis (OA), an increase of 113% since 1990. The progression of diabetic neuropathy can be controlled through a healthy lifestyle and medication adherence, as can osteoarthritis through healthy living and physical exercise. This study applies family doctor services by identifying internal and external risk factors, clinical problems, and patient management based on Evidence-Based Medicine, focusing on the patient, family, and community. This study is a case report that collects primary data through anamnesis, physical examination, home visits, and environmental data, along with secondary data from the patient’s medical records. Assessments were conducted holistically, both qualitatively and quantitatively, from the beginning to the end of the study. Mrs. Y, 61 years old, presented with complaints of numbness and tingling in all four limbs accompanied by pain in both knees, with a history of diabetes for 15 years. The patient was diagnosed with diabetic neuropathy and osteoarthritis. In this case, diagnosis and management were carried out according to relevant theories and journals. Following intervention, there was a reduction in clinical symptoms and an increase in knowledge among the patient and her family. The diagnosis and management of this patient were conducted holistically, patient-centered, with a family approach, and community-oriented. Based on several current theories and studies, there was an improvement in the patient’s family knowledge.
Co-Authors Diana Mayasari Hanna Mutiara Hendra Tarigan Sibero