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All Journal Medula Majority JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Hanna Mutiara
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Dentistry Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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1. Kementrian Kesehatan Republik Indonesia. Pusat data dan informasi tuberkulosis. Jakarta: InfoDATIN; 2018. 2. Sharma SK, Mohan A, Sharma A. Miliary tuberculosis: A new look at an old foe. J Clin Tuberc. 2016; 3(1):13–27. 3. Ray S. Diagnosis and mana Anugerah Indah Sari; Roro Rukmi Windi; Hanna Mutiara
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.285

Abstract

Gross motor development is one of children development which must detect in young age for minimize developmental delayed. Age under 3 is a Golden Period which children brain is rapidly develop. Stimulation is a method that can increase children development. Stimulation in age 0-12 month need for optimizing children development. To know mother charactheristic based on giving gross motor stimulation age 0-12 months old at posyandu in Kelurahan Penengahan Raya Kecamatan Kedaton Bandar Lampung. Design of this observational descriptive to 27 mom who had children 0-12 months old at posyandu in Kelurahan Penengahan Raya Kecamatan Kedaton Bandar lampung. The data were taken in the from primary data from questionnaire to score maternal stimulation. We can get mother age 25-35 yo is 18 people and age <25 yo is 9 people. For job distribution, mother who work as housewife is 23 people, enterpreneur is 2 people and employee is 2 people. For last education distribution, elementary is 1 person, JHS is 10 people, SHS is 14 people and collage is 2 people Conclusion: good gross motor stimulation is given by mother who have 25-35 yo, work as housewife and their last education grade is senior high school.
Hubungan Antara Lama Menderita Diabetes Melitus Tipe 2 Dengan Kejadian Peripheral Arterial Disease Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Kedaton Kota Bandar Lampung Adinda Ayu Lintang S; Hanna Mutiara; Merry Indah Sari; Muhartono; Ryan Falami
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.286

Abstract

Diabetes mellitus is a metabolic disease with characteristics of hyperglycemia occurs due to abnormalities of insulin secretion, insulin function, or both. Diabetes mellitus causes various kinds of complications, one of which is peripheral arterial disease (PAD). PAD is is a condition characterized by atherosclerotic occlusive disease of the lower extremities. The purpose of this study to knowing the relationship between the length of suffering type 2 diabetes mellitus and the incidence of peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus in Puskesmas Kedaton Kota Bandar Lampung. This research is correlative analytic with cross sectional approach. The study was conducted November 2017. The population in this study were all patients with DM type 2 who joined prolanis activities at Puskesmas Kedaton of Bandar Lampung city. The number of research samples are 40 respondents with consecutive sampling technique. This results has 17 male and 23 women respondents. The average duration of DM is 9.8 years. Respondents with normal were 52.5%, mild PAD 12.5%, moderate 32.5% and severe 2.5%. Spearman test results of both variables obtained p value of 0.001 and correlation value 0.651. The conclusion is there are relationship between length of suffering type 2 diabetes mellitus and the incidence of peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus in Puskesmas Kedaton of Bandar Lampung city.
Potensi Ekstrak Kulit Batang Bakau Minyak (Rhizophora apiculata) Sebagai Larvasida Terhadap Larva Aedes Aegypti Dzakwan Cedri Ketierteu; Jhons Fatriyadi Suwandi; Putu Ristyaning Ayu Sangging; Hanna Mutiara
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.577

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease in humans which is transmitted by the Aedes aegypti mosquito as a vector which causes many cases of death. In Indonesia, the number of cases of dengue fever deaths will be 705 cases in 2021. Alternative natural insecticides are needed to avoid potential resistance to chemical insecticides. Rhizophora apiculata stem bark contains active compounds, namely saponins, flavonoids, alkaloids, and tannins which are larvicidal. The purpose of this study was to determine the larvicidal effectiveness of Rhizophora apiculata stem bark extract. This study used a laboratory experimental research design with a post test only control group design pattern. Divided into 6 groups, namely negative control, 0.045%, 0.09%, 0.18%, 0.36%, and positive control. Each group contained 25 larvae in 20 ml of Rhizophora apiculata stem bark extract solution with 4 repetitions. The data analysis used was univariate data analysis to find which concentration caused the highest death of Aedes aegypti larvae. From the research results, it was found that the average mortality of larvae from 4 repetitions at concentrations of 0.045%, 0.09%, 0.18%, and 0.36% were 68%, 97%, 99%, and 100% respectively.
Pendekatan Diagnostik, Faktor Risiko, dan Tatalaksana Neuropati Diabetik Muhammad Labib MY Bima; Fidha Rahmayani; Hanna Mutiara
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.555

Abstract

Diabetic neuropathy is the most common complication of diabetes mellitus. As many 25% of people with diabetes mellitus in the world and 54% in Indonesia suffer from diabetic neuropathy. Electro-diagnostic studies are best used for the diagnosis of diabetic neuropathy. In addition, the diagnosis can be made by scoring Diabetic Neuropathy Symptom (DNS) and Diabetic Neuropathy Examination (DNE). Patients with diabetes mellitus must pay attention to risk factors such as carbohydrate intake, physical activity, duration of suffering, and medication adherence to prevent complications of diabetic neuropathy. Management of diabetic neuropathy can be done with drugs or other supportive therapy. This article uses a literature review method from various national and international journal references with the following search keywords: prevalence, diagnosis, risk factors, and management of diabetic neuropathy.
Polusi Udara dan Permasalahan terhadap Kulit Marcella Dena Fernanda; Hendra Tarigan Sibero; Hanna Mutiara
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.590

Abstract

Pollution has been shown to increasingly play a role in several common ailments, and the effects on the skin are no exception. Indoor and outdoor pollutants are widely distributed in urban and rural environments. WHO defines air pollution as contamination of the outdoor (ambient) and indoor (household) environment by any chemical, physical or biological agent that alters the natural characteristics of the atmosphere. Inhaled or ingested pollutants can be distributed throughout the body through the systemic circulation, making the exposed air a target for contaminants in the superficial and deep layers of the skin. The mechanisms by which pollutants may interact with human skin may differ based on each agent and its specific characteristics. Basic and clinical studies have provided growing evidence of the interaction of pollutants with the skin. Pollutants can activate skin metabolic and inflammatory pathways and induce oxidative stress by lowering antioxidant levels in particular. The skin is also a target for another known source of oxidative stress, namely UV radiation. The interaction of pollutants with UV light or the human skin microbiota requires further clinical investigation to evaluate their specific impact on skin health. Both outdoor and indoor pollution were found to increase signs of skin aging such as facial lentigines and wrinkles. Living in a polluted environment can also reduce skin moisture, increase the rate of sebum excretion and possibly worsen symptoms of chronic inflammatory skin diseases in both children and adults. Home location, type of work and diet all lead to internal and external exposure to a variety of pollutants, with clinical consequences that can accumulate or synergize. Pollutants are only one component of exposure which means that both internal and external factors must be considered when establishing pollution protection measures, which necessitates the development of standard methods for their evaluation. This literature review provides an overview of how pollutants affect the health of the skin.
MIASTENIA GRAVIS: ETIOLOGI, PATOFISIOLOGI, MANIFESTASI KLINIS, PENEGAKKAN DIAGNOSIS DAN TATALAKSANA KHAIRUNNISA SALSABILA; Hanna Mutiara; Rizki Hanriko
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.598

Abstract

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating weakness of the extraocular, bulbar, and proximal muscles. Muscle weakness that occurs will worsen with activity and improve after rest. Myasthenia gravis is caused by the presence of autoantibodies on the postsynaptic membrane at the neuromuscular-junction (NMJ), such as antibodies against acetylcholine receptors, MuSK and LRP4. Myasthenia gravis is a rare neurological disease, the incidence is only about 1.7-21.3 per 1,000,000, has a bimodal distribution in women, with a peak of incidence at the age of 30-50 years. Men have a higher proportion after age 50. Myasthenia gravis is mostly a treatable disease but can result in significant morbidity and even death, so writing this literature review aims to discuss the pathophysiology, clinical manifestations, diagnosis and current treatment options for MG so as to increase the accuracy of the very early diagnosis. plays an important role in early management, as well as prevention of worse disease progression. The diagnosis of MG is based on anamnesis, neurological examination, electrodiagnostics, serology, and CT scan of the chest to see the presence of thymoma. The main treatment for MG is cholinesterase enzyme inhibitors and immunosuppressive agents. Symptoms that are resistant to primary treatment modalities or that require rapid resolution, such as in a myasthenic crisis, may require plasmapheresis or intravenous immunoglobulin treatment. Thymectomy can also be done.
PERBEDAAN KONTAMINASI TELUR SOIL TRANSMITTED HELMINTH PADA TANAH DI DAERAH PEDESAAN DAN PERKOTAAN Alvan Muhammad Hibatullah Santoso; Hanna Mutiara; Giska Tri Putri; Jhons Fatriyadi Suwandi
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.479

Abstract

Soil Transmitted Helminth is an infection that causes malnutrition, anemia, growth retardation. Transmission is through contact with eggs or larvae in the soil. Cases of STH infection in Indonesia are high in areas of poor sanitation, poor hygiene and lack of understanding of clean and healthy lifestyles. Therefore, this study aims to determine the contamination of STH eggs on soil in rural and urban areas. This research is a cross-sectional study with purposive sampling. The number of samples is 90 soil sample points in rural and urban areas and then the univariate and bivariate analysis tests are carried out using the pearson chi-square Test. The number of STH contamination in rural areas was 29 out of 90 samples with 26 samples of Ascaris lumbricoides, 2 samples of Hookworm, and 1 sample of Trichuris trichiura. STH egg contamination in urban areas was 22 out of 90 samples with details of 17 samples of Ascaris lumbricoides, 3 samples of Hookworm, and 2 samples of Trichuris trichiura. Based on the results of the pearson chi-square Test analysis, a p-value of 0.467 was obtained. There is no difference in contamination of STH eggs on soil in rural and urban areas.
Efek Pemberian Minyak Buah Merah pada Penurunan Parasitemia pada Mencit yang Diinfeksi dengan Plasmodium berghei Elma Sandya Putri; Jhons Fatriyadi Suwandi; Hanna Mutiara; Asep Sukohar
MAJORITY Vol 10 No 2 (2021): MAJORITY
Publisher : Majority

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Abstract

Malaria is one of the endemic infectious disease cases in several areas in Indonesia. Indonesia had the highest malaria incidence in Southeast Asia. High levels of morbidity and mortality and antimalarial resistance problems encourage the need to find new antimalarial agents, such as red fruit. Red fruit contains many antioxidants and has been reported to have effect of reducing parasitemia. This study aims to determine the effects of red fruit oil on reducing parasitemia in mice infected with Plasmodium berghei. This experimental study with a post-test only control group design used 32 mice as samples and divided it into 8 groups (control group (aquadest); chloroquine group 0.5 mg / grBB, red fruit oil group doses of 0.1 cc, 0.2 cc and 0.4 cc; combination group of red fruit oil doses of 0.1 cc, 0.2 cc and 0.4 cc, with chloroquine 0.5 mg/grBB). Research data was processed using Mann-Whitney test and Kruskal Wallis test because the data didn’t meet one way ANOVA test requirements. The results showed effect of red fruit oil on decreasing parasitemia in mice infected with Plasmodium berghei (p
Efek Suplementasi Madu terhadap Penurunan Frekuensi Diare Akut pada Anak di RSUD Dr. H. Abdul Moeloek Bandar Lampung Nidia Putri Meisuri; Roro Rukmi Windi Perdani; Hanna Mutiara; Asep Sukohar
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

Diarrheal diseases is still health problems of the world with high number of mortality and morbidity. Traditional medicine which has a bitter taste and antibacterial effect, one of which has the effect of antibacterial honey, bitter taste and antioxidants. This study to find out the potential effects of honey supplementation on reducing the frequency of acute diarrhea in children in the Dr. H. Abdul Moeloek. This study used quasi-experimental design with nonequivalent control group design. Subjects of study were children with acute diarrhea who were divided into two intervention groups and control group, each group amounted to 15 respondents. Data obtained directly from research subjects through primery data. From the data obtained then the analysis is performed using unpaired samples t-test. This study indicates the frequency of first-day acute diarrhea of intervention group was more than control group. The frequency of acute diarrhea on the second, third and fourth days in intervention group was less than children who were controls group. The statistical test results show the potential effects of honey supplementation on decreasing frequency of acute diarrhea. Provision of honey supplementation was proven to reduce the frequency of acute diarrhea in the Dr. H Abdul Moeloek Hospital Bandar Lampung.
Faktor-Faktor yang Berhubungan dengan Status Imunisasi Lanjutan Pentavalen (DPT-HB-Hib) di Wilayah Kerja Puskesmas Labuhan Ratu Kota Bandar Lampung Tahun 2018 Nanda Salsabila Itsa; Roro Rukmi Windi Perdani; Hanna Mutiara
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

The Pentavalent (DPT-HB-Hib) immunization is one of advanced immunization programmed by the goverment to prevent diseases such as diphteria, pertussis, tetanus, B-type hepatitis, and B-type Haemophilus influenzae. The lowest advanced pentavalent immunization coverage in Bandar Lampung is located at Labuhan Ratu Health Center (26,9%). Several factors are related to pentavalent immunization administration such as mother’s knowledge, mother’s attitude, mother’s job status, affordability of health services, and the role of health workers. Purpose of this research is to find out the factors related to advanced pentavalent immunization in the working area of Labuhan Ratu Public Health Bandar Lampung. This research used analytic observational method with cross-sectional approach. The sample of the research is 42 respondents in which live at work area of Labuhan Ratu Public Health Bandar Lampung city through purposive sampling method. The result of univariate analysis was 42,9% of respondents had complete advanced Pentavalent immunization status and the other 64,3% respondents had incomplete status. The result of bivariate analysis showed some variables had a correlation with advanced pentavalent immunization status such as mother’s knowledge (p-value 0,029), mother’s attitude (p-value 0,022) and mother’s job status (p value 0,014). Meanwhile, some variables had no correlation with advanced pentavalent immunization status such as mother’s education (p-value 0,384), affordability to health services (p-value 0,344) and the role of health workers (p-value 0,571). The conclusion is mother’s knowledge, mother’s attitude, and mother’s job status are correlated to advanced Pentavalent immunization in the working area of labuhan ratu public health Bandar Lampung city 2018.
Co-Authors Adinda Ayu Lintang S Ajeng Fitria N Alvan Muhammad Hibatullah Santoso Andi Nabila Maharani Insan Anugerah Indah Sari Asep Sukohar Betta Kurniawan, Betta Dzakwan Cedri Ketierteu Efrida Warganegara Elma Sandya Putri Ermin Rachmawati Ety Apriliana Fahma Azizaturrahmah Febri Nadyanti Fitria Saftarina Giska Tri Putri Guntur Sulistio Harmeida Risa Helmi Ismunandar Hendra Tarigan Sibero Jhons Fatriyadi Suwandi Johns Fatriyadi Suwandi Jyoti Krisna Murti Khairun Nisa KHAIRUNNISA SALSABILA Kurnia Fitri Aprilliana Marcella Dena Fernanda Merry Indah Sari Muhammad Labib MY Bima Muhammad Morsa Habibie Muhammad Yusran Muhartono Nanda Salsabila Itsa Nani Indah Hardiyanti Nidia Putri Meisuri Rahmayani, Fidha Rani Himayani Rika Lisiswanti Riska Wulandari Rizki Hanriko Roro Rukmi Windi Roro Rukmi Windi Perdani, Roro Rukmi Ryan Falami Sangging, Putu Ristyaning Ayu Sulinawati Sulinawati Tresa Ivani Saskia Viera Rininda Mauli Dinar Yusnita Eka Rahayu