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All Journal Jurnal Ilmiah Wahana Pendidikan
Nissa Khalida Hanum
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Kajian Mekanisme Molekuler Golongan Obat Antihipertensi Dalam Menghambat Angiotensin-Converting Enzyme (ACE) Jekmal Malau; Munir Alinu Mulki; Nur Komala Fitri; Najla Yusiana Wahyudi; Priscinya Christiana Debora; Mulidini Mulidini; Nolla Olipia Elva Megrian; Nissa Khalida Hanum
Jurnal Ilmiah Wahana Pendidikan Vol 9 No 2 (2023): Jurnal Ilmiah Wahana Pendidikan
Publisher : Peneliti.net

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.478 KB) | DOI: 10.5281/zenodo.7571470

Abstract

Hypertension or increased blood pressure is a chronic disease that requires long treatment, even for life. Patients with hypertension must control their blood pressure to avoid complications. In the body, there are components of the renin-angiotensin system, namely the angiotensin-converting enzyme (ACE) which can indirectly increase blood pressure, so the treatment is to inhibit ACE. In this article, the method used is by literature study of several accredited journals that has published from 2012 to 2022. ACE inhibitor class drugs are often used for the treatment of hypertension because they have a mechanism of inhibiting the conversion enzyme peptidyl dipeptidase, so that angiotensin I is not hydrolyzed to angiotensin II and can be contributed for dilating blood vessels as well so that it effectively lowers blood.
Co-Authors Jekmal Malau Mulidini Mulidini Munir Alinu Mulki Najla Yusiana Wahyudi Nolla Olipia Elva Megrian Nur Komala Fitri Priscinya Christiana Debora