Musdalifah Musdalifah
Study Program of Veterinary Medicine, Faculty of Medicine, Hasanuddin University

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Case Study of Nephritis in Domestic Cats (Felis Catus) Male in Veterinary Teaching Clinic of Hasanuddin University Waode Santa Monica; Indah Windy Octaviyani; Musdalifah Musdalifah
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 3 No. 2, JULY 2019
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v3i2.8001

Abstract

ABSTRACT: A pet such as a domestic cat (Felis Catus) with a sterile male sex aged 1 year 7 months with a body weight of 3.7 kg where the animal is affected by urinary system disorders namely Nephritis. Nephritis is kidney inflammation that can occur in the glomerulus, pyelum or tubules. Clinical symptoms shown in patients include polyuria, decreased appetite, and vomiting. For the diagnosis of Nephritis clinically evaluated based on changes in urination behavior, palpation of the dorsal abdominal caudal thoracic is temporarily labored based on a urine dipstick test containing protein ++ (± 100 mg / dL), leukocytes valued at +, urine specific gravity of 1,015 while based on ultrasound examination thickening of the renal cortex, medullary and cortical border is not apparent, renal size is 4.21 cm, kidney capsules that appear hyperechoic, and ascites in the abdomen. Cats treated with isotonic fluid infusion fluids, wet and dry diet diets, antibiotics, multivitamins, and anti-inflammatory. Inpatient animals for 4 days showed improvement in clinical symptoms, namely drinking quite well, starting to stand up, there was movement for activities, and urine was clearer.
The Effect of Ajwa Dates Fruit Extract (Phoenix dactylifera L.) on the Creatinine Levels in White Rats (Rattus norvegicus) Induced by Meloxicam Toxic Doses Yuliani Suparmin; Risha Catra Pradhany; Musdalifah Musdalifah; Dian Fatmawati; Nur Afzah Zainuddin; Eka Nurdiana
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 6 No 2, JULY 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v6i2.18666

Abstract

Meloxicam is an NSAID (non-steroidal anti-inflammatory drug) which is an antipyretic analgesic drug as well as a non-steroidal anti-inflammatory drug that is widely used by the public, including pet owners, in treating their favorite animals without advice from a veterinarian. The use of meloxicam in excessive doses can trigger kidney damage. Based on related research, meloxicam can cause cell death due to nephrotoxicity. Ajwa dates have the highest antioxidant activity among other types of dates, suppress lipid peroxidation, prevent cell damage, and have nephroprotective abilities. The aim of this study was to determine the effect of giving ajwa date fruit extract on creatinine levels of male wistar rats induced by toxic dose of meloxicam. This research is an experimental research with the research design used is the Pre Test-Post Test Design Group. The total sample used was 24 male wistar rats which were divided into 4 groups, namely the negative control group (K1) which was given 1% Na CMC on days 1-18, the positive control group (K2) which was given meloxicam 30mg/kgBW on day 1- 4 and 1% Na CMC on days 5-18, treatment group 1 (K3) was given meloxicam 30mg/kgBW on days 1-4 and ajwa date fruit extract 150mg/kgBW on days 5-18, treatment group 2 (K4) given meloxicam 30 mg/kg body weight on days 1-4 and ajwa date fruit extract 300 mg/kg body weight on days 5-18. Blood sampling was carried out on day 19 to measure creatinine levels. The results of data analysis using the Independent T-Test test for groups K1 and K2 were P < 0.05, which means that there is a statistically significant relationship between the administration of meloxicam and the increase in creatinine levels. The results of data analysis using the independent T-Test test for the K2 group with K3 and K4 were P<0.05, which means that there is a statistically significant relationship between the administration of ajwa date fruit extract and the decrease in creatinine levels of rats given a toxic dose of meloxicam. Keywords: Ajwa dates, creatinine, meloxicam, nephroprotective, white rat
Feline Infectious Peritonitis (FIP) in Himalayan Cats at Hasanuddin University Educational Veterinary Clinic: Feline Infectious Peritonitis (FIP) in Himalayan Cats at Hasanuddin University Educational Veterinary Clinic waode santa monica; Carisma Sumule; Abdul Wahid Jamaluddin; Musdalifah Musdalifah
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 6 No 2, JULY 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v6i2.19321

Abstract

Feline infectious peritonitis (FIP) is a viral disease, this disease can cause death in various types of cats but is not zoonotic. Feline infectious peritonitis (FIP) is caused by Feline corona virus (FCoV) from the family Coronaviridae, genus Alphacoronavirus. The purpose of writing a case study is to find out how to diagnose and treat FIP ​​in cats. Methods for diagnosing FIP include anamnesis, clinical examination, ultrasonographic examination (USG) and laboratory examinations consisting of hematological tests and Rivalta tests. The results of the physical examination showed changes in appetite, diarrhea, weakness, 8% dehydration, Body Condition Score 2, abdominal enlargement. Laboratory results using ultrasound showed accumulation of fluid in the abdominal cavity and kidney enlargement 4.29 cm, while the results of hematological examinations decreased the value of the MCV 33 fL, MCH 12 pg and WBC 1.37 10^3 /uL while the MCHC was 53.7 g/dL has increased, the results of the Rivalta test showed a positive result of FIP found the presence of jellyfish-shaped deposits. Handling of FIP cases is treated with antibiotics, multivitamins, fluid therapy, and feed management.