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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Scripta Biologica
Rendy Setya Wardana
State Intelligence College, University Of Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Law, Crime, Criminology & Criminal Justice Social Sciences Other

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ANTIBACTERIAL CAPACITY OF Streptomyces ISOLATE FROM A MANGROVE PLANT RHIZOSPHERE Avicennia marina Rendy Setya Wardana; Dini Ryandini; Oedjijono Oedjijono
Scripta Biologica Vol 4, No 2 (2017)
Publisher : Fakultas Biologi | Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (918.875 KB) | DOI: 10.20884/1.sb.2017.4.2.433

Abstract

This research was conducted to obtain Streptomyces isolates from Avicennia marina rhizosphere capable of inhibiting E. coli and S. aureus growth, to investigate the capability and the characteristics of its antibacterial compound. This study completed the isolation by applying pour plate method on SCN agar medium. Antagonistic screening and selection processes were carried out by diffusion and dilution methods. Observation on the characteristic of the antibacterial compound applied was TLC method and MIC assay. This research confirmed the antibacterial compound capability by applying bioautography assay. Parameters measured consisted of inhibition zone diameter, Rf value on a bioautography plate, and the lowest concentration capable of inhibiting bacterial growth. Out of 16 isolates of Streptomyces obtained, Streptomyces 404 showed higher antagonistic activity than others. Inhibition zone diameter reached 20–25 mm in E. coli and S. aureus growth, respectively. TLC assay showed three spots in which two of them confirmed antibacterial activity in the bioautography assay that yielded Rf values of 0.47 for E. coli and 0.72 for S. aureus, while MIC assay showed that the lowest extract concentration inhibited bacterial growth was 20%.
Assesment Of 2012 National Health System (Skn) Detection and Curative Respond Capabilities (Covid-19 Case Study) Rendy Setya Wardana; Isroil Samihardjo; Ede Surya Darmawan
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.72 KB) | DOI: 10.36418/syntax-literate.v8i1.11276

Abstract

Covid-19 is a new emerging disease that spreads at Indonesia in 2020. The 2012 SKN as a legislative tool that applies and plays a role in health development aims to achieve the highest level of human health in Indonesia. However, the Covid-19 pandemic has proven that the health development that has been carried out has not been able to overcome the threat of the SARS-CoV-2 virus. This is evidenced by the large number of fatalities experienced by the people of Indonesia due to infection with the SARS-CoV-2 virus. The outbreak of Covid-19 was followed by large fatalities due to massive SARS-CoV-2 virus infection throughout 2020 until early 2022. The introduction of the disease that has occurred for 2 years should have been able to be anticipated by SKN through the capabilities of the SKN component regarding efforts to detect SARS-CoV-2. CoV-2 and curative efforts against Covid-19 patients. So in this study, an effort to compare the ability of the SKN response was carried out regarding detection and curative efforts in the first year of the pandemic and the second year of the pandemic. The comparison was carried out to see how the different SKN responses to the ongoing pandemic. The results are only testing indicators on detection capabilities that have good readiness (quantity refers to the standard), while other indicators such as surveillance, hospital capacity and health workers are still in an inadequate situation. So it is necessary to strengthen the SKN in an effort to anticipate the threat of a pandemic in the future
Co-Authors Dini Ryandini Ede Surya Darmawan Isroil Samihardjo Oedjijono Oedjijono