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All Journal Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat
Brian Eka Rahman
3Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine- Dr. Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia,
Religion Agriculture, Biological Sciences & Forestry Arts Education Social Sciences

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Exhaled Breath Analysis for COVID-19 Investigation: Clinical instruments or Scientific Toys? Isna Mahmudah; Naufali Rizkiawan; Husin Thamrin; Brian Eka Rahman; Hasan Maulahela; Yudith Annisa Ayu Rezkitha; Yoshio Yamaoka; Muhammad Miftahussurur
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2023): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/abdimas.v6i1.2910

Abstract

The COVID-19 pandemic was crucial worldwide. Ongoing COVID-19 disease investigation methods were primarily based on molecular and serological detection. These instruments are invasive and necessarily require the use of trained personnel. Non-invasive COVID-19 investi-gation methods could help diagnose and monitor the outbreak. Because the SARS-CoV-2 virus is non-living, it lacks its metabolism. Different infectious diseases can release volatile organic compounds (VOCs), resulting in specific VOCs. All of these are metabolic products primarily produced locally in the respiratory system and systemically via blood circulation. We overview the clinical applications in the COVID-19 investigation and summarize the methodological is-sues. Numerous VOCs in the exhaled breath have the prospects to distinguish patients from healthy people and people infected with COVID-19. It is hard to define COVID-19 using VOCs from exhaled breath. Due to a lack of standardization in data collecting and processing proce-dures, their use in clinical practice is hampered. There are insufficient studies and external vali-dation to determine whether exhaled breath analysis adds value to the diagnostic and follow-up processes for COVID-19 infection. In conclusion, the use of VOCs in exhaled breath as a marker for COVID-19 infection has not been validated for clinical use.
Co-Authors Hasan Maulahela Isna Mahmudah Muhammad Miftahussurur Naufali Rizkiawan Thamrin, Husin Yoshio Yamaoka Yudith Annisa Ayu Rezkitha