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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal SainHealth International Journal of Social Service and Research Holistik Jurnal Kesehatan
Wijayanti, Christina Destri Wiwis
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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GAMBARAN HEMOGLOBIN DAN NEUTROFIL PASIEN KEMOTERAPI KANKER PAYUDARA DI ONKOLOGI CENTER RSUD Dr. SOETOMO SURABAYA: HEMOGLOBIN AND NEUTROPHIL OF BREAST CANCER CHEMOTHERAPYPATIENTS AT THE ONCOLOGY CENTER OF Dr. SOETOMO HOSPITAL, SURABAYA Rachmaningtyas, Arie; Sundari, Titik; Rini, Yenny Puspa; Wijayanti, Christina Destri Wiwis
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

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Abstract

Breast cancer management is chemotherapy. One of the negative impacts of chemotherapy is affecting hemoglobin and neutrophils. This study aims to determine the description of Hemoglobin levels and Neutrophil counts in breast cancer patients undergoing chemotherapy stage 1 (early) and stage 6 (late) at the Oncology Center of Dr. Soetomo Hospital, Surabaya. This study is an observational study with a retrospective design. The sample in this study was some breast cancer patients undergoing chemotherapy stage 1 (early) and 6 (late) at the Oncology Center of Dr. Soetomo Hospital, Surabaya, which was taken as many as 25 people by purposive sampling. Purposive sampling. The study was conducted in the Oncology Center laboratory of Dr. Soetomo Hospital, Surabaya. This study was conducted from October to December 2022. The results of the study showed that breast cancer patients undergoing stage 1 chemotherapy mostly had normal hemoglobin as many as 13 people (52%) with an average Hb level of ± 12.34 g / dL and normal neutrophils as many as 23 people (92%) with an average neutrophil level of ± 4412 cells / µL. In stage 6 chemotherapy, most had low hemoglobin as many as 13 people (52%) with an average Hb level of ± 11.78 g / dL and normal neutrophils as many as 24 people (96%) with an average number of neutrophils of 4202.68 cells / µL.
CORRELATION BETWEEN MAGNESIUM AND CALCIUM LEVELS ON HEALTH IN THE ELDERLY WITH DEGENERATIVE TYPE 2 DIABETES MELLITUS Wijayanti, Christina Destri Wiwis; Ayu, Diva Sukma; Mariska, Nabila Refi
International Journal of Social Service and Research Vol. 5 No. 1 (2025): International Journal of Social Service and Research
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v5i1.1189

Abstract

Diabetes Mellitus (DM) is a metabolic disorder characterized by elevated blood glucose levels due to decreased insulin secretion from pancreatic beta cells or insulin resistance. Magnesium and calcium are essential minerals that play crucial roles in various enzymatic activities, significantly influencing important biological functions, particularly in relation to metabolic syndrome. The purpose of the research is to investigate the correlation between magnesium and calcium levels in the serum of elderly individuals with type 2 diabetes mellitus. The study method is descriptive observation with cross-sectional studies. The examination sample used 25 serum samples of people with diabetes with age inclusion criteria over 50 years old without any other degenerative diseases. The analysis of the data from the results of the study was then carried out by the SpSS test of the relationship between magnesium levels and the condition of type 2 DM, especially in the context of aging and its impact on metabolic health. Based on the examination of magnesium levels using the xylidil blue method, 23 patients (92%) showed normal results, while 2 patients (8%) showed numbers above normal on average. There was no significant relationship between blood sugar and magnesium levels, blood sugar with calcium levels, and between magnesium with calcium with a significance of p 0.058, p 0.179, and p 0,114, respectively. The findings of this study could enhance the understanding of the complex interactions between these essential minerals and their potential roles in managing metabolic syndrome, ultimately contributing to better health outcomes for older adults with DM.
PERBANDINGAN UJI Treponema pallidum Haemagglutination Assay (TPHA) DAN IMUNOKROMATOGRAFI SEBAGAI DETEKSI SIFILIS di PUSKESMAS MEDAENG: COMPARISON OF Treponema pallidum Haemagglutination Assay (TPHA) TEST AND IMMUNOCHROMATOGRAPHY AS SYPHILIS DETECTION AT MEDAENG PUBLIC HEALTH CENTER Romadhon, Desi Fitriatur; Wijayanti, Christina Destri Wiwis; Sundari, Titik; Harmoko, Deni
Jurnal SainHealth Vol. 8 No. 2 (2024): September 2024
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v8i2.16861.65-69

Abstract

Syphilis is a sexually transmitted infection caused by the bacteria Treponema pallidum. Syphilis detection can be done using the Treponema pallidum Haemagglutination Assay (TPHA) method and immunochromatography. Treponema pallidum Haemaglutination Assay (TPHA) is a specific antibody test to detect Treponema pallidum but the process is long and expensive, compared to fast and relatively cheap immunochromatography. This study aimed to compare the Treponema pallidum Haemagglutination Assay (TPHA) method and immunochromatography as syphilis detection by looking at their positive and negative reaction percentage. The type of research used was descriptive-analytical observation. The results of the Treponema pallidum Haemagglutination Assay (TPHA) examination were positive for 10 samples (50%) and negative for 10 samples (50%). Meanwhile, positive immunochromatography was in 8 samples (40%) and negative for 12 samples (60%). It can be concluded that TPHA and immunochromatography have a different result. Keywords: syphilis, immunochromatography, TPHA, sensitivity, specificity
Hubungan rasio monosit/high density lipoprotein (HDL) dengan indeks massa tubuh pada pasien dengan penyakit jantung koroner Raharjo, Budiono; Kurniawati, Renny; Wijayanti, Christina Destri Wiwis; Linggawan, Stephani; Sumarpo, Anton; Bintoro, Siprianus Ugroseno Yudho
Holistik Jurnal Kesehatan Vol. 19 No. 2 (2025): Volume 19 Nomor 2
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i2.651

Abstract

Background: The incidence of coronary heart disease continues to increase every year. The monocyte/high density lipoprotein (HDL) ratio has recently been proposed as a new predictor and prognostic indicator in cardiovascular disease. Obesity is one of the risk factors for coronary heart disease that can be measured using body mass index (BMI). Purpose: To determine the relationship between the monocyte/high density lipoprotein (HDL) ratio and body mass index (BMI) in patients with coronary heart disease. Method: This observational analytical study with a cross-sectional approach used research subjects with coronary heart disease at Mitra Keluarga Hospital, Waru during the period of January 2023 - January 2024. The sample in this study was taken by purposive sampling. The correlation test of the monocyte/high density lipoprotein (HDL) ratio with body mass index (BMI) was carried out using SPSS software version 29. Results: Body mass index in coronary heart patients was found that most patients were included in the type I obesity category as many as 9 people (30%). The monocyte/HDL ratio in coronary heart patients was found to be an average of 20.28. Conclusion: There is no significant relationship between the monocyte/HDL ratio and BMI in coronary heart patients. Suggestion: Further researchers can conduct similar research in hospital institutions with a larger sample size.   Keywords: Body Mass Index; High Density Lipoprotein; Monocyte.   Pendahuluan: Penyakit jantung koroner terus mengalami peningkatan setiap tahunnya. Rasio monosit/high density lipoprotein (HDL), baru-baru ini diusulkan sebagai prediktor dan indikator prognosis baru pada penyakit kardiovaskular. Obesitas merupakan salah satu faktor resiko penyakit jantung koroner yang dapat diukur menggunakan indeks massa tubuh (IMT). Tujuan: Untuk mengetahui hubungan rasio monosit/high density lipoprotein (HDL) dengan indeks massa tubuh (IMT) pada pasien dengan penyakit jantung koroner. Metode: Penelitian analitik observasional dengan pendekatan cross sectional ini menggunakan subjek penelitian dengan penyakit jantung koroner di Rumah Sakit Mitra Keluarga, Waru selama rentang waktu bulan Januari 2023 – Januari 2024. Sampel dalam penelitian ini diambil secara purposive sampling. Uji korelasi rasio monosit/high density lipoprotein (HDL) dengan indeks massa tubuh (IMT) dilakukan dengan piranti lunak SPSS versi 29. Hasil: Indeks massa tubuh pada pasien jantung koroner didapatkan sebagian besar pasien termasuk dalam kategori obesitas tipe I sebanyak 9 orang (30%). Rasio monosit/HDL pada pasien jantung koroner didapatkan rata-rata sebesar 20.28. Simpulan: Tidak ditemukan adanya hubungan yang signifikan antara rasio monosit/HDL dengan IMT pasien jantung koroner. Saran: Peneliti selanjutnya dapat melakukan penelitian serupa pada instansi rumah sakit dengan jumlah sampel yang lebih besar.   Kata Kunci: High Density Lipoprotein; Indeks Massa Tubuh; Monosit.
Hubungan Serum Iron (SI) dan Kadar Hemoglobin (Hb) sebagai Gambaran Potensi Anemia Defisiensi Besi pada Lansia Wijayanti, Christina Destri Wiwis; Sundari, Titik; Syaifah, Nur
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i6.15764

Abstract

Lansia adalah seseorang yang telah mencapai usia 60 tahun ke atas, pria maupun wanita yang mengalami penurunan kemampuan adaptasi dan tidak dapat memenuhi kebutuhan sehari- harinya sendiri. Lansia berpotensi mengalami anemia karena perubahan karakteristik lansia, penyakit penyerta penurunan penyerapan nutrisi. Anemia merupakan sebuah keadaan dimana kadar hemoglobin (Hb) atau sel darah merah (eritrosit) mengalami penurunan. Hemoglobin berperan sebagai pengangkut oksigen (O2) dari paru – paru keseluruh tubuh dan menukarkannya dengan karbindioksida (CO2) dari jaringan untuk dikeluarkan melalui paru – paru. Zat besi (Fe) diperlukan dalam hemopoesis (pembentukan darah), yaitu dalam sintesis hemoglobin. Penelitian ini bertujuan untuk melihat hubungan antara zat besi (serum iron) dan kadar hemoglobin sebagai potensi anemia defisiensi besi pada lansia di Kec.Taman Kab. Sidoarjo. Penelitian ini menggunakan data primer metode deskriptif analitik observasional. Jumlah responden 25 orang. Penelitian ini menggunakan uji Pearson correlation untuk melihat tingkat hubungan antara SI dan Hb. Hasil penelitian menunjukkan adanya hubungan yang kuat antar SI dan Hb dengan p=0,000 dan r=0,649. Didapatkan nilai rata – rata kadar hemoglobin 10,52 g/dl dengan hasil normal sebanyak 12 % dan rendah 88%. Didapatkan nilai rata – rata serum iron 91,68 μg/dl dengan hasil normal sebanyak 92 % dan rendah 8 %. Lansia dengan kadar hemoglobin rendah belum tentu serum iron-nya rendah. Nilai Hb yang rendah tanpa dipengaruhi penurunan SI dapat disebabkan karena kekurangan nutrisi lain dan penyakit kronis (inflamasi).
Co-Authors Anton Sumarpo Ayu, Diva Sukma Bintoro, Siprianus Ugroseno Yudho Harmoko, Deni Kurniawati, Renny LINGGAWAN, STEPHANI Mariska, Nabila Refi Rachmaningtyas, Arie RAHARJO, BUDIONO Rini, Yenny Puspa Romadhon, Desi Fitriatur Syaifah, Nur TITIK SUNDARI