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Ilhamjaya Pattelongi
Hasanuddin University
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Analysis Of Changes In Endothelin-1 (Et-1) And F2-Isoprostane Levels After The 30 Km Event In The Makassar Bike Community At The "Bike For Health" Event Nur Fadhilah Irfani; Ilhamjaya Pattelongi; Andi Ariyandy; Andi Wardihan Sinrang; Djohan Aras; Nukhrawi Nawir
COMPETITOR: Jurnal Pendidikan Kepelatihan Olahraga Vol 15, No 1 (2023): February
Publisher : UNIVERSITAS NEGERI MAKASSAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/cjpko.v15i1.43620

Abstract

This study aims to determine changes in ET-1 and F2-isoprostane levels after a 30 km cycling event in the Makassar cycling community. This study used a pre-experimental with one group pretest-posttest design on 30 male cyclists aged 30-60 years. The sampling technique used is the purposive sampling method. The pretest was carried out the day before the 30 km cycling event, then the post-test was carried out 2 hours after the cycling event. Blood testing is done with an ELISA Kit. Data were analyzed using the Wilcoxon test to see changes in ET-1 and F2-isoprostane levels after cycling events. The correlation of changes in ET-1 and F2-isoprostane levels was analyzed using the Spearman test. The results of this study found that the 30 km cycling event had no significant effect on changes in levels of ET-1 (p=0.082) and F2-isoprostane, which means that it has no potential to increase the body's oxidative stress (p=0.688). Changes in ET-1 levels did not correlate with changes in F2-isoprostane levels which showed no association with impaired cardiovascular function (p=0.102).
Analysis Of Changes In Nitric Oxide (NO) And F2-Isoprostane Levels After The 30 Km Cycling Event In The Makassar Bike Community Risna Yunita; Ilhamjaya Pattelongi; Andi Ariyandy; Andi Wardihan Sinrang; Djohan Aras; Nukhrawi Nawir
COMPETITOR: Jurnal Pendidikan Kepelatihan Olahraga Vol 15, No 1 (2023): February
Publisher : UNIVERSITAS NEGERI MAKASSAR

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/cjpko.v15i1.43631

Abstract

This study aims to determine changes in Nitric Oxide (NO) and F2-Isoprostane levels after a 30 km cycling event in the Makassar cycling community. This research was a pre-experimental study with a one-group pretest & post-test design with 30 cyclists as subjects in the city of Makassar, men aged 30-60 years. Blood sampling was carried out pre-event and post-event cycling as far as 30 Km. Measurement of F2-Isoprostane & Nitric Oxide levels using the ELISA method. Data analysis used the Wilcoxon test to see changes in Nitric Oxide (NO)  and F2-Isoprostane levels after participating in a 30 Km cycling event. Data analysis using the Mann-Whitney test was used to see differences in changes in Nitric Oxide (NO)  and F2-Isoprostane levels in the age group, average speed, exercise category, BMI, and smokers. Spearman test to see the correlation of changes in Nitric Oxide (NO)  and F2-Isoprostane levels. The results of this study found that the 30 km cycling event had a significant effect on changes in Nitric Oxide (NO)  levels which could improve the function of the vascular endothelium with p=0.0001. Meanwhile, the 30 km cycling event had no significant effect on changes in F2-Isoprostane levels, which meant that it had no risk of oxidative stress and tissue damage (p=0.688). There is no positive correlation between changes in Nitric Oxide (NO)  levels and changes in F2-Isoprostane levels, which means that changes in the repair of vascular endothelial function seem to suppress free radical production which leads to oxidative stress after cycling as far as 30 Km.
Co-Authors Andi Ariyandy Andi Wardihan Sinrang Djohan Aras Nukhrawi Nawir Nukhrawi Nawir Nur Fadhilah Irfani Risna Yunita