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Gambaran Hipokromasi Eritrosit dan Mean Corpuscular Hemoglobin (MCH) pada Penderita Ginjal Kronis di RSUD Kraton Kabupaten Pekalongan Subur Wibowo; Fitrianingsih Fitrianingsih; Muhamad Salasa Dis Nahari
Jurnal Kebidanan Harapan Ibu Pekalongan Vol 10 No 1 (2023): Jurnal Kebidanan Harapan Ibu Pekalongan
Publisher : LPPM Akademi Kebidanan Harapan Ibu Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37402/jurbidhip.vol10.iss1.231

The prevalence of Chronic Kidney Disease (CKD) in Indonesia in 2013-2018 has increased from 0.2% to 0.38%. Patients with CKD have low erythropoietin, so that the production of erythrocytes is disrupted and causes anemia. Anemia in CKD includes the type of normocytic-normochromic. Hypochromic occurs because iron reserves cannot be used in the process of erythropoiesis, resulting in decreased synthesis of hemoglobin. Erythrocytes will appear pale on the peripheral blood smear. Hypochromic is clinically associated with iron deficiency anemia. Changes in the color of the erythrocytes also indicate a state of immaturity of the cells, which causes erythrocyte hypochromacy. This study aims to determine MCH levels and erythrocyte hypochromatous abnormalities in patients with chronic kidney disease on hemodialysis therapy at Kraton Hospital, Pekalongan Regency. The research method used is descriptive, namely the type of research that describes the phenomenon of the object under study in the form of a narrative. The results of the analysis of the MCH values in the normal category were 25 samples (71.4%), the MCH values in the low category were 10 (28.6%). There were 9 samples (25.7%) of mild hypochromacy in the mild hypochromic category, 15 (42.9%) of moderate hypochromic category, 11 (31.4%) of severe hypochromic category. So it can be concluded that the MCH values in the normal category are more than in the low category and hypocracy in the moderate category is more than mild and severe hypochromacy.

Gambaran Kadar Jumlah Eritrosit Pada Pekerja Bengkel Motor Yang Terpapar Asap Kendaraan Bermotor di Sekitar Wiradesa Subur Wibowo; Suparyati
Jurnal Medika Husada Vol. 2 No. 1 (2022): Maret : Jurnal Medika Husada
Publisher : Akademi Analis Kesehatan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59744/jumeha.v2i1.6

Kendaraan bermotor di Indonesia mengalami peningkatan jumlah setiap tahunnya. Peningkatan tersebut menambah juga bengkel motor untuk pelayanan perbaikan dan perawatan. Dampak negatif dari proses perawatan dan perbaikan motor tersebut adalah tingginya tingkat polusi udara serta emisi, gas buangan kendaraan motor di tempat bengkel tersebut. Paparan dari asap kendaraan bermotor dapat menyebabkan keracunan bagi tubuh manusia. Paparan timbal dengan kadar rendah yang berlangsung secara terus menerus dalam jangka waktu lama akan menghambat pembentukan sel darah merah. Efek keracunan timbal akan berpengaruh pada hasil indeks eritrosit. Tujuan penelitian ini untuk mengetahui gambaran kadar jumlah eritrosit pada pekerja bengkel motor yang terpapar asap kendaraan bermotor di daerah Wiradesa kabupaten Pekalongan. Metode yang di lakukan dalam penelitian ini adalah deskriptif analitik. Penelitian di lakukan di laboratorium Hematologi Akademi Analis Kesehatan Pekalongan dengan sampel 25 orang, metode pemeriksaan perhitungan secara mikroskopis. Hasil penelitian menunjukkan bahwa 9 dari 25 responden memiliki nilai eritrosit normal dengan jumlah persentase 46% dan 14 responden memiliki nilai eritrosit rendah dengan jumlah persentase 64%

Gambaran Jumlah Leikosit Pada Perajin Batik Yang Terpapar Obat Batik di Desa Karangjompo Tahun 2021 Subur Wibowo; Nur Halimah
Jurnal Medika Husada Vol. 1 No. 2 (2021): Oktober : Jurnal Medika Husada
Publisher : Akademi Analis Kesehatan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59744/jumeha.v1i2.19

Pewarna sintesis atau obat batik merupakan senyawa turunan dari hidrokarbon aromatic seperti benzene, toluene, naftalena, dan antrasena. Senyawa tersebut dapat melakukan kontak dengan tubuh melalui paru-paru, sistem pencernaan. Uap Benzena akan langsung diabsobsi oleh tubuh kemudian dengan cepat didistribusikan ke seluruh tubuh melalui pembuluh darah. Melalui pembuluh darah senyawa benzene di simpan di dalam sumsum tulang. Untuk mengetahui jumlah leukosit pada pengrajin batik yang terpapar obat batik di Desa Karangjompo tahun 2021. Metode penelitian yang digunakan adalah deskriptif, yaitu untuk mengetahui gambaran jumlah leukosit pada pengrajin batik yang terpapar obat batik di Desa Karangjompo tahun 2021. Jumlah populasi 58 dan didapat 17 sampel berdasarkan rumus slovin dan kriteria inklusi, eksklusi. Pemeriksaan dilakukan menggnakan kamar hitung improved neubauer dengan metode manual. Hasil pemeriksaan jumlah leukosit pada pengrajin batik yang terpapar obat batik di Desa Karangjompo tahun 2021 diperoleh nilai tinggi 8 dengan presentase (47%), normal 6 dengan presentase (35,3%) dan rendah 3 dengan presentase (17,7%). Hasil penelitian menunjukkan bahwa dari 17 sampel pada pemeriksaan jumlah leukosit pada pengrajin batik yang terpapar obat batik di Desa Karangjompo tahun 2021. Jumlah leukosit Tinggi dengan presentase (47%) responden.

PENURUNAN KADAR GLUKOSA DARAH YANG DIKERJAKAN SECARA LANGSUNG,DITUNDA 1,3 DAN 6 JAM PADA SERUM SIMPAN DENGAN SUHU 2-8 ºC Indah Fitriyani; Subur Wibowo
Jurnal Medika Husada Vol. 2 No. 2 (2022): Oktober: Jurnal Medika Husada
Publisher : Akademi Analis Kesehatan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59744/jumeha.v2i2.27

Pemeriksaan glukosa darah merupakan pemeriksaan rutin bagi penderita diabetes. Pemeriksaan yang cepat, tepat dan murah sudah menjadi tuntutan bagi semua laboratorium klinik. Pemberian hasil yang sesuai klinis akan membantu dokter dalam menegakkan diagnosis dan memberikan pengobatan. Jumlah pasien yang banyak terkadang membuat petugas laboratorium kewalahan dan harus menunda pemeriksaan, akan tetapi parameter tertentu akan menurun kadarnya jika ditunda pemeriksaanya tanpa penambahan zat pengawet. Glukosa darah yang diperiksa beberapa saat setelah pengambilan sampel dapat menurun kadarnya. Penurunan kadar glukosa disebabkan adanya proses glikolisis sel-sel darah. Jika glikolisis terjadi diluar tubuh sesudah sampel darah dikeluarkan tanpa zat pengawet maka akan menyebabkan penurunan kadar gula darah dengan kecepatan 7 mg/dl per satu jam. Untuk mengetahui persentase penurunan kadar glukosa darah yang dikerjakan secara langsung,ditunda 1,3 dan 6 jam pada serum simpan dengan suhu 2-8 °C. Jenis penelitian yang dilakukan adalah penelitian deskriptif analitik. Pengambilan sampel menggunakan perhitungan menurut Arikunto didapat sampel sejumlah 22 mahasiswa, dikerjakan dengan metode GOD-PAP dengan spektrofotometer. Berdasarkan pemeriksaan kadar glukosa darah pada 22 mahasiswa Akademi Analis Kesehatan Pekalongan didapatkan rata-rata hasil glukosa darah dengan penundaan 1 jam adalah 102,82 mg/dl(7%), 3 jam 96,61 mg/dl (12,7%) dan 6 jam 87,97 mg/dl (18,8%). Terdapat penurunan pemeriksaan kadar gula darah setelah penundaan 1,3 dan 6 jamdengan variasi 7%, 12,7% dan 18,8%.

Gambaran MCH, MCV dan MCHC Pada Ibu Hamil Trimester II di Puskesmas Wonokerto I Kabupaten Pekalongan Subur Wibowo; Anisah Fauziyah
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 2 No. 1 (2024): Februari : Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v2i1.201

Anemia is a dangerous condition that can occur in pregnant women, this case often occurs in the first, second and third trimesters. Anemia is a reduction or reduction in the capacity of the blood to carry oxygen. Based on data from the Indonesian Ministry of Health (Kemenkes), the population of pregnant women who experience anemia is 37.1%. The proportion of anemia in pregnant women in urban areas is 36.4% and in rural areas is 37.8%. The most common type of anemia in pregnant women is microcytic hypochromic anemia (59% of pregnant women are anemic). This study aims to determine the description of MCH, MCV and MCHC in pregnant women in the second trimester at the Wonokerto I Community Health Center, Pekalongan Regency. The research method used is descriptive. The research was conducted at the Wonokerto I Community Health Center Laboratory, Pekalongan Regency. The total sample was 20 second trimester pregnant women. Using the Hematology Analyzer Dirui BCC 3600. From 20 samples of pregnant women in the second trimester, the MCV was obtained for 11 Normocytic pregnant women (80-100 fL), 8 Microcytic pregnant women (<80 fL), and 1 Macrocytic pregnant woman (>100 fL). . MCH description of 9 Normochrome pregnant women (27-34 pg), 10 Hypochrome pregnant women (<27 pg) and 1 Hyperchrome pregnant mother (>34 pg). MCHC description of 9 pregnant women is Normal (32-36 g/dL), 10 pregnant women are Low (<32 g/dL) and 1 pregnant woman is High (>36 g/dL). The conclusion of this study is that from 20 samples of second trimester pregnant women, the most common type of anemia was Hypochromic Normocytic Anemia with low and normal MCHC index levels.

Overview of Hemoglobin and Hematocrit Levels in Pregnant Women in the First, Second, and Third Trimesters at Kraton Pekalongan Regional General Hospital Subur Wibowo; Amelia Wulan Febriyanti
INDOGENIUS Vol 5 No 1 (2026): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v5i1.669

Background & Objective: Pregnancy is the union of spermatozoa and ovum followed by implantation. Pregnancy with certain signs may indicate the occurrence of dangers that can occur during pregnancy, which if not reported or detected early can cause death to the mother and fetus. One way to keep mothers and babies healthy during pregnancy is by conducting pregnancy checkups. This study aims to determine the levels of hemoglobin and hematocrit in pregnant women in their first, second, and third trimesters at the Kraton Regional General Hospital in Pekalongan Regency. Method: This study used a descriptive design with 30 samples taken using total sampling from pregnant women in their first, second, and third trimesters at the Kraton Regional General Hospital in Pekalongan Regency. Hemoglobin levels were measured using a spectrophotometer, and hematocrit levels were measured using a microhematocrit method. Result: The results showed that pregnant women in the first trimester had hemoglobin levels of 9.18% and hematocrit levels of 31.4%, pregnant women in the second trimester had hemoglobin levels of 12.8% and hematocrit levels of 35.3%, and pregnant women in the third trimester had hemoglobin levels of 13.28% and hematocrit levels of 37.1%. Conclusion: It can be concluded that in the first trimester, there is a decrease in HB and HT levels due to plasma volume increasing faster than the number of red blood cells, and in the second and third trimesters, there is a greater increase in plasma volume than in red blood cell volume.

Gambaran Hipokromasi Eritrosit dan Mean Corpuscular Hemoglobin (MCH) pada Penderita Ginjal Kronis di RSUD Kraton Kabupaten Pekalongan Subur Wibowo; Fitrianingsih Fitrianingsih; Muhamad Salasa Dis Nahari
Jurnal Kebidanan Harapan Ibu Pekalongan Vol. 10 No. 1 (2023): Jurnal Kebidanan Harapan Ibu Pekalongan
Publisher : LPPM Akademi Kebidanan Harapan Ibu Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37402/jurbidhip.vol10.iss1.231

The prevalence of Chronic Kidney Disease (CKD) in Indonesia in 2013-2018 has increased from 0.2% to 0.38%. Patients with CKD have low erythropoietin, so that the production of erythrocytes is disrupted and causes anemia. Anemia in CKD includes the type of normocytic-normochromic. Hypochromic occurs because iron reserves cannot be used in the process of erythropoiesis, resulting in decreased synthesis of hemoglobin. Erythrocytes will appear pale on the peripheral blood smear. Hypochromic is clinically associated with iron deficiency anemia. Changes in the color of the erythrocytes also indicate a state of immaturity of the cells, which causes erythrocyte hypochromacy. This study aims to determine MCH levels and erythrocyte hypochromatous abnormalities in patients with chronic kidney disease on hemodialysis therapy at Kraton Hospital, Pekalongan Regency. The research method used is descriptive, namely the type of research that describes the phenomenon of the object under study in the form of a narrative. The results of the analysis of the MCH values in the normal category were 25 samples (71.4%), the MCH values in the low category were 10 (28.6%). There were 9 samples (25.7%) of mild hypochromacy in the mild hypochromic category, 15 (42.9%) of moderate hypochromic category, 11 (31.4%) of severe hypochromic category. So it can be concluded that the MCH values in the normal category are more than in the low category and hypocracy in the moderate category is more than mild and severe hypochromacy.

Overview of Triglyceride Levels and Estimated VLDL in Atherosclerosis Development among Patients over 50 Years Mohamad Zaul Haq; Bekti Mastiadji; Subur Wibowo
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12789

Atherosclerosis is a chronic arterial disease caused by disorders of lipid metabolism, leading to the formation of atherosclerotic plaques. Elevated triglyceride levels are associated with increased production of Very Low-Density Lip oprotein (VLDL), which plays an important role in the process of atherogenesis and contributes to an increased risk of cardiovascular disease. Therefore, the measurement of triglyceride levels and the estimation of VLDL are important for the early detection of atherosclerosis risk, particularly in patients aged over 50 years. This study aimed to describe triglyceride levels and VLDL estimation in relation to atherosclerosis formation among patients aged over 50 years at QIM Batang Hospital. This study employed a descriptive research design involving 27 patients aged over 50 years. Triglyceride levels were measured using the enzymatic colorimetric GPO-PAP method with a chemistry analyzer, while VLDL levels were estimated using the Friedewald formula (VLDL = triglycerides/5). Data were analyzed descriptively and presented as frequency distributions and percentages. The laboratory results showed that normal triglyceride levels were found in 10 respondents (37.04%), borderline-high triglyceride levels in 10 respondents (37.04%), and high triglyceride levels in 7 respondents (25.92%). High estimated VLDL levels were observed in 17 respondents (62.96%), whereas normal estimated VLDL levels were found in 10 respondents (37.04%). These findings indicate that most patients aged over 50 years had elevated estimated VLDL levels, suggesting a potential increase in the risk of atherosclerosis development.

Hubungan Kadar Hemoglobin Dan Hematokrit Dengan Lama Sakit Pada Pasien Tuberkulosis Paru Di Puskesmas Karanganyar Aninda Breliyana; Subur Wibowo
Borneo Nursing Journal (BNJ) Vol. 8 No. 2 (2026)
Publisher : Akademi Keperawatan Yarsi Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61878/bnj.v8i2.1059

Tuberkulosis paru (TB paru) merupakan penyakit infeksi yang disebabkan oleh Mycobacteriumtuberculosis dan masih menjadi masalah kesehatan masyarakat di Indonesia. Infeksi kronis akibat TBdapat memengaruhi sistem hematologi, terutama kadar hemoglobin (Hb) dan hematokrit (Ht), yangberkaitan dengan kondisi klinis serta lama sakit pasien. Penelitian ini bertujuan untuk mengetahuihubungan kadar hemoglobin dan hematokrit dengan lama sakit pada pasien tuberkulosis paru diPuskesmas Karanganyar. Penelitian menggunakan desain analitik korelasi dengan pendekatan cross-sectional. Sampel penelitian sebanyak 32 pasien TB paru yang memenuhi kriteria inklusi diperolehmelalui teknik total sampling. Data lama sakit diperoleh dari rekam medis, sedangkan pemeriksaankadar hemoglobin dan hematokrit dilakukan menggunakan metode Point of Care Testing (POCT).Analisis data meliputi uji normalitas Shapiro–Wilk dan uji korelasi Pearson. Hasil penelitianmenunjukkan rata-rata kadar hemoglobin sebesar 12,3 g/dL, dengan 25 responden (78%) memilikikadar hemoglobin rendah dan 7 responden (22%) normal. Rata-rata kadar hematokrit sebesar 37,2%,dengan 23 responden (72%) memiliki kadar hematokrit rendah, 8 responden (25%) normal, dan 1responden (3%) tinggi. Analisis statistik menunjukkan adanya hubungan antara lama sakit dengankadar hemoglobin dan hematokrit pada pasien tuberkulosis paru. Dengan demikian, kadar hemoglobindan hematokrit dapat digunakan sebagai parameter pendukung dalam memantau kondisi klinis pasienTB selama menjalani pengobatan.

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