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PENGARUH PEMBERIAN SUPLEMEN VITAMIN C TERHADAP KADAR GLUKOSA DARAH PUASA PADA PASIEN PENDERITA DIABETES MELITUS TIPE 2: THE EFFECT OF VITAMIN C ADMINISTRATION ON FASTING BLOOD GLUCOSE LEVELS IN PATIENTS WITH DIABETES MELITUS TYPE 2 Heny Yulia Rahmawati; Mustaming; Sresta Azahra
GEMA KESEHATAN Vol. 15 No. 1 (2023): Juni 2023
Publisher : POLTEKKES KEMENKES JAYAPURA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47539/gk.v15i1.402

Abstract

Pemberian antioksidan dapat menjadi salah satu upaya mengatasi stress oksidatif. Salah satu antioksidan yaitu vitamin . Vitamin C adalah salah satu antioksidan yang bermanfaat dalam menghambat aktivitas radikal bebas dan berperan dalam meningkatkan jumlah insulin, berkontribusi mencegah penurunan massa sel beta dan mengurangi toksisitas glukosa,  memodulasi aksi insulin pada penderita DM, terutama dalam metabolisme glukosa non oksidatif. Tujuan penelitian ini untuk mengetahui pengaruh pemberian suplemen vitamin C terhadap kadar glukosa darah puasa pada pasien diabetes melitus tipe 2. Vitamin C mempunyai struktur yang mirip dengan glukosa sehingga vitamin C dapat menggantikannya dalam proses glikolisis non enzimatik. Vitamin C sebagai antioksidan dapat meningkatkan insulin sehingga mampu menurunkan kadar glukosa darah dan mengurangi toksisitas dari glukosa.  Metode penelitian bersifat quasi eksperimen dengan pre and post test without control. Teknik sampel consecutive sampling. Sampel penelitian sebanyak 32 sampel dengan responden diberikan suplemen vitamin C dosis 250mg/hari selama 5 hari. Analisa data menggunakan uji Wilcoxon. Hasil penelitian didapatkan rata-rata kadar glukosa darah puasa sebelum konsumsi suplemen vitamin C sebesar 255mg/dL sedangkan rata-rata kadar glukosa darah puasa setelah konsumsi suplemen vitamin C sebesar 252,47 mg/dL. Hasil uji Wilcoxon didapatkan p <  (0,05), yaitu p value = 0,032 yang berarti ada pengaruh konsumsi suplemen vitamin C terhadap kadar glukosa darah puasa pada pasien penderita diabetes melitus tipe 2. Kesimpulan penelitian yaitu ada pengaruh konsumsi suplemen vitamin C terhadap kadar glukosa darah puasa pada pasien penderita diabetes melitus tipe 2. Kata kunci: Glukosa Darah, Pasien diabetes mellitus Tipe 2, Vitamin C   Giving antioxidants can be an effort to overcome oxidative stress. One of the antioxidants is vitamins. Vitamin C is a good antioxidant and helps inhibit free radical activity and contributes to increasing the amount of insulin, preventing a decrease in beta cell mass and reducing glucose toxicity, modulating insulin action in DM patients, especially in non-oxidative glucose metabolism. This study aimed to determine the effect of vitamin C supplements on fasting blood glucose levels in patients with type 2 diabetes mellitus. The research method is quasi-experimental with pre and post-test without control—consecutive sampling technique. The research sample consisted of 32 samples with respondents being given vitamin C supplements at a dose of 250 mg/day for five days—data analysis using the Wilcoxon test. The results showed that the average fasting blood glucose level before taking vitamin C supplements was 255mg/dL. In comparison, the intermediate fasting blood glucose level after taking vitamin C supplements was 252.47 mg/dL. Wilcoxon test results obtained p < (0.05), i.e., p-value = 0.032, meaning that vitamin C supplement consumption affects fasting blood glucose levels in patients with type 2 diabetes mellitus. Fasting blood in patients with type 2 diabetes mellitus. Equations. Keywords: Blood glucose, Type 2 diabetes mellitus patients, Vitamin C
Profil Hitung Jumlah dan Jenis Leukosit Pada Anak Terinfeksi Kecacingan Kota Samarinda Ade Tasya Halim; Sresta Azahra
Jurnal Sains dan Teknologi Laboratorium Medik Vol 9 No 2 (2023): November 2023
Publisher : Akademi Kesehatan John Paul II Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52071/jstlm.v9i2.137

Abstract

Helminthic infections are caused by helminth parasites. Helminthic worms are health problems that affect the defenses of the human immune system such as leukocytes. Children infected with helminthic worms are characterized by an increase in the number of eosinophils due to an immune response to helminthic infection. The purpose of knowing the profile of counting the number and type of leukocytes in children infected with worms. Type of descriptive research with cross sectional design. The total population is 187 children with 9 children infected with worms in Samarinda City. This study was carried out by fecal examination (microscopic), leukocyte count examination (counting chamber) and leukocyte count (differential count). Analysis of data in univariate form. The results of the study found 9 children (5%) infected with worms, 5 children (3%) male aged 6-12 years and 4 children (2%) female aged 8-10 years. Types of worm eggs obtained 5 children (56%) Ascaris lumbricoides, 2 children (22%) Trichuris trichiura and 2 children (22%) Hymenolepis nana. The number of leukocytes in infected children is within normal limits (4,500-13,500 μL). The type of abnormal leukocytes was obtained by 4 children (45%) who had elevated eosinophils. Conclusion The number of leukocytes in infected children is within normal limits and the type of leukocytes that have increased in the number of eosinophils (45%) indicates an immune response to helminthic infection.
GAMBARAN JAMUR PENYEBAB TINEA MANUUM PADA PEKERJA CUCI PIRING RUMAH MAKAN DI WILAYAH SAMARINDA SEBERANG Nurdiana, Annisa; Sresta Azahra; Nurul Anggrieni
Jurnal Kesehatan dan Pembangunan Vol 14 No 1 (2024): Jurnal Kesehatan dan Pembangunan
Publisher : LPPM STIKes Mitra Adiguna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52047/jkp.v14i27.266

Abstract

Dermatophytosis is a superficial mycosis caused by a fungus. Dermatophytosis is often referred to as tinea infection and is classified according to the part of the body affected. Like tinea manuum which is a dermatophytosis infection on the skin of the palms, back of the hands and fingers. Dishwashing workers tend to be easily infected with the tinea manuum fungus because their working environment is humid and requires them to always be in contact with water. This study aims to determine the description of the fungus that causes tinea manuum in restaurant dishwashing workers in the Samarinda Seberang area. The number of samples in this study involved 35 restaurant workers washing dishes in the Samarinda Seberang area. This type of research is descriptive with a cross sectional research design. The data collected in this study were in the form of primary data and were obtained through direct interviews with the relevant dishwashing workers as well as macroscopic and microscopic laboratory examinations. The results of this study showed that the percentage of respondents' characteristics based on gender was 63% male and 37% female also the percentage of tinea manuum in restaurant dishwashing workers in the Samarinda Seberang Region was 29%. It was concluded that the tinea manuum infection that attacks the dishwashing workers at the Samarinda Seberang area is caused by a dermatophyte fungus, namely Trichophyton sp.