Article Per Year (5 Year)
p-Index From 2020 - 2025
0.983
P-Index
This Author published in this journals
All Journal Indonesian Journal of Cardiology Indonesian Journal of Medicine Heart Science Journal Cardiovascular and Cardiometabolic Journal (CCJ) Narra J Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Irnizarifka
Cardiologist, Department Of Cardiology And Vascular Medicine, Sebelas Maret University, Solo, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 9 Documents
Search

 1 
Nilai Prediktif Mri Kardiak Pasca Stemi Peran Late Enhancement Irnizarifka I; Sony Hilal Wicaksono; Ario Soeryo Kuncoro; Manoefris Kasim
Jurnal Kardiologi Indonesia Vol. 34, No. 3 Juli - September 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i3.342

Abstract

Forum Pencitraan Kardiovaskular edisi sebelumnya membahas tentang peran Magnetic Resonancec Imaging (MRI) kardiak pada kasus Penyakit Jantung Koroner dalam kondisi akut maupun kronik. Dalam forum kali ini, kami sajikan contoh kasus penggunaan MRI kardiak pada pasien pasca Infark Miokard Akut Elevasi ST (IMAEST) yang dilakukan pemeriksaan MRI kardiak saat perawatan sebagai stratifikasi risiko pasien pasca IMAEST. Penyakit kardiovaskular masih menjadi penyebab morbiditas dan mortalitas tertinggi di dunia, dengan penyakit arteri koroner (PAK) sebagai manifestasi utamanya.1 Dengan semakin berkembangnya manajemen serangan jantung akut, setidaknya 70% pasien yang dirawat di rumah sakit dengan infark miokard akut (IMA) berhasil melewati fase akutnya. Namun, konsekuensi jangka panjang pasca serangan akut tetap dapat terjadi meskipun intervensi fase akut telah dilakukan. Dengan demikian, ketepatan waktu dalam mendiagnosis IMAEST menjadi sangat penting.
Acute Coronary Syndrome in Well Trained Young Adult: A Rare Cases Aprila Aqmarina Indah; Praditya Virza Ramadhan; Vireza Pratama; Haikal Haikal; Irnizarifka Irnizarifka
Cardiovascular and Cardiometabolic Journal Vol. 1 No. 2 (2020): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v1i2.2020.69-76

Abstract

Acute Coronary Syndrome (ACS) has been observed in the older population (>40 years old), sedentary lifestyle and unhealthy behavior. Recently, there is an increase of ACS reported in the younger population even without a sedentary lifestyle. We report a case of a well-trained 25-years old man that came with late presentation of ST elevation myocardial infarction (STEMI) occurred 10 minutes after vigorous exercise. His traditional risk factor was a smoker. Electrocardiogram (ECG) showed a pathological Q wave in anteroseptal lead and T wave inversion in anterior lead with elevated cardiac biomarker. Primary percutaneous coronary intervention (PPCI) was performed due to prolonged chest pain and it showed subtotal occlusion in mid left anterior descending artery (LAD) with high thrombus burden. Drug eluting stent (DES) was implanted at mid LAD and GPIIb/IIIa inhibitor and low molecule weight heparin was given with good clinical result.
Conservative Management for Anterior STEMI Complicated by Ventricular Septal Rupture Nanda Eka Sri Sejati; Habibie Arifianto; Irnizarifka -
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.510

Abstract

Ventricular septal rupture is a rare complication of acute myocardial infarction but with a very high mortality, most often caused by severe hemodynamic failure. Conservative treatment is very inefficient with over 90% mortality rate; surgery is recommended as definitive treatment. A case of 67-year-old woman with chest pain since 1 day accompanied by shortness of breath and diaphoresis. Cardiac auscultation showed a 3/6 systolic murmur without thrill. ST elevation at the anterior lead was found in ECG. Echocardiography detected a rupture in interventricular septal with left-to-right shunt. The patient was diagnosed with anterior ST elevation myocardial infarction (STEMI) complicated by ventricular septal rupture. A conservative management was given without intra-aortic balloon pump placement and surgical operation due to patient’s rejection. One month post treatment, the patient exhibited a relatively stable hemodynamic with moderate to severe activity limitation. Ruptur septum ventrikel merupakan komplikasi infark miokard akut yang jarang, namun mortalitasnya sangat tinggi, paling sering karena kegagalan hemodinamik berat. Penanganan konservatif sangat tidak efisien dengan tingkat kematian lebih dari 90 %; intervensi bedah direkomendasikan menjadi tatalaksana definitif. Seorang wanita 67 tahun mengeluh nyeri dada sejak 1 hari disertai sesak nafas dan diaforesis. Auskultasi jantung menunjukkan bising sistolik 3/6 tanpa thrill. EKG mendapatkan elevasi segmen ST di sadapan anterior. Pada ekokardiografi ditemukan ruptur septum ventrikel dengan left-to-right shunt. Pasien didiagnosis infark miokard akut elevasi ST anterior dengan ruptur septum ventrikel. Manajemen konservatif tanpa pemasangan intra-aortic balloon pump ataupun tindakan operatif karena pasien menolak. Satu bulan pasca perawatan, hemodinamik relatif stabil dengan keterbatasan aktivitas sedang-berat.
Conservative Management for Anterior STEMI Complicated by Ventricular Septal Rupture Nanda Eka Sri Sejati; Habibie Arianto; Irnizarifka
Cermin Dunia Kedokteran Vol. 46 No. 3 (2019): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.498

Abstract

Ventricular septal rupture is a rare complication of acute myocardial infarction but with a very high mortality, most often caused by severe hemodynamic failure. Conservative treatment is very inefficient with over 90% mortality rate; surgery is recommended as definitive treatment. A case of 67-year-old woman with chest pain since 1 day accompanied by shortness of breath and diaphoresis. Cardiac auscultation showed a 3/6 systolic murmur without thrill. ST elevation at the anterior lead was found in ECG. Echocardiography detected a rupture in interventricular septal with left-to-right shunt. The patient was diagnosed with anterior ST elevation myocardial infarction (STEMI) complicated by ventricular septal rupture. A conservative management was given without intra-aortic balloon pump placement and surgical operation due to patient’s rejection. One month post treatment, the patient exhibited a relatively stable hemodynamic with moderate to severe activity limitation. Ruptur septum ventrikel merupakan komplikasi infark miokard akut yang jarang, namun mortalitasnya sangat tinggi, paling sering karena kegagalan hemodinamik berat. Penanganan konservatif sangat tidak efisien dengan tingkat kematian lebih dari 90 %; intervensi bedah direkomendasikan menjadi tatalaksana definitif. Seorang wanita 67 tahun mengeluh nyeri dada sejak 1 hari disertai sesak nafas dan diaforesis. Auskultasi jantung menunjukkan bising sistolik 3/6 tanpa thrill. EKG mendapatkan elevasi segmen ST di sadapan anterior. Pada ekokardiografi ditemukan ruptur septum ventrikel dengan left-to-right shunt. Pasien didiagnosis infark miokard akut elevasi ST anterior dengan ruptur septum ventrikel. Manajemen konservatif tanpa pemasangan intra-aortic balloon pump ataupun tindakan operatif karena pasien menolak. Satu bulan pasca-perawatan, hemodinamik relatif stabil dengan keterbatasan aktivitas sedang-berat.
The Sub-Analysis of HFmrEF and HFrEF Group in CORE-HF Registry : When being Good is Not Enough Irnizarifka, Irnizarifka; Wasyanto, Trisulo; Chau, Titus; Arifianto, Habibie
Jurnal Kardiologi Indonesia Vol 44 No 1 (2023): Indonesian Journal of Cardiology: January - March 2023
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1545

Abstract

Background : As the prevalence of heart failure (HF) kept rising each year, the burden caused by it also escalating, especially in terms of economic burden. This is urging the physician to quickly tackle the problem. Although HFrEF medications were developing vastly, the outcome of HF in real world still varies. This indicates another approach is still needed to manage HFrEF/HFmrEF comprehensively. This paper is aimed to give an overview of HFrEF and HFmrEF epidemiological data, based on CORE-HF real world data. Methods : The CORE-HF is a single-center, prospective-cohort registry, which enrolls all patients with chronic HF, that were recruited consecutively from the outpatient Sebelas Maret HF Clinic. Both enrollment and follow-up have been performed since January 2018 until December 2022. Variables recorded consists of baseline characteristics, risk factors, subjective indicators, objective diagnostic assessments, therapies, and outcomes (readmission and mortality). Results : The population of this registry was younger (58.7 ± 12.14) compared to other HF registries, with more multi comorbidities. The number of HFrEF patient was higher than HFmrEF (77.7% vs 22.3%), with clinically higher mortality rate (7.2% in the 1st year and 18.2% in the next year). Although triple therapy initiation and uptitration were excellent in number, the mortality rate during second year of follow-up was higher than other registries. We found non-compliant behavior to be responsible for those results. Conclusion : Based on CORE-HF sub-analysis of the HFrEF and HFmrEF groups, adherence to HF guidelines is the main but not the only key leading to lower mortality and rehospitalization. Our data provide satisfying low hard outcomes, but solving the non-compliance behavior and optimizing the non-pharmacological approach should be done comprehensively by the HF team.
Effects of early ivabradine therapy in patients with acute heart failure: A meta-analysis and systematic review Nuraini, Yulianna Cahya; Irnizarifka, Irnizarifka; Prameswari, Hawani Sasmaya; Simangunsong, Robby Martin
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.10

Abstract

BACKGROUND: Although ivabradine is the agent of choice for reducing heart rate, its use in acute heart failure patients remains unclear. OBJECTIVES: To evaluate the potential of in-hospital ivabradine administration in reducing heart rate, the risk of rehospitalization, mortality, and clinical profile in acute heart failure patients using a meta-analysis approach. METHODS: The study was designed as a meta-analysis conducted from August to September 2024. We selected several database sources for the search strategy, including PubMed, Google Scholar, ProQuest, British Medical Journal, and American Journal of Cardiology. Data on the outcomes of ivabradine treatment compared to standard therapy were collected to determine cumulative point estimates. For statistical analysis, we used the Mantel–Haenszel test for categorical data or inverse variance for continuous data. RESULTS: We included 11 articles in the study. Our findings indicated that, in comparison to the standard therapy group, the ivabradine group was associated with improvements in resting heart rate, a reduction in the risk of rehospitalization, a decrease in cardiovascular mortality, a reduction in all-cause mortality, a shorter length of stay, improvements in New York Heart Association (NYHA) classification, better Left Ventricular Ejection Fraction (LVEF), and improved B-type Natriuretic Peptide (BNP) / N-terminal pro b-type Natriuretic Peptide (NT-proBNP) levels. CONCLUSION: In conclusion, this study has revealed the beneficial effects of using ivabradine for the treatment of acute heart failure.  TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian     TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back
Anticoagulant Management of Mechanical Heart Valve Patients During Perioperative Surgery: A Case Report Wasyanto, Trisulo; Yudhistira, Yoga; Anggraini, Nutria; Yasa, Ahmad; Irnizarifka, Irnizarifka
Indonesian Journal of Medicine Vol. 8 No. 4 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.08.04.01

Abstract

Background: Patients with mechanical heart valves require lifelong oral anticoagulation. It will be a dilemma if a patient with a mechanical heart valve has surgery. This case report aims to discuss how to interrupt oral anticoagulants and bridging therapy in patients with mechanical heart valves who will be undergoing non-cardiac surgery. Case Report: A 26-year-old pregnant woman, G1P0A0, aterm with a mechanical mitral valve, will have elective Sectio Caesarian Transperitonealis (SCTP) surgery and Intra Uterine Device (IUD) insertion. The patient had a history of mitral valve replacement surgery (MVR) in 2014 and was routinely treated with 4 mg of warfarin at night. From the examination, blood pressure was 120/80 mmHg, heart rate was 90 beats per minute, and pulse rate was 90 beats per minute. The ECG examination found sinus rhythm with 1st-degree atrioventricular block, right axis deviation, 90 beats per minute, and left atrial enlargement. We decided to have oral anticoagulant interruption and bridging therapy by stopping warfarin three days before surgery. When the international normalized ratio (INR) falls <2, patients are given heparin injections (UFH) with an APTT target of 1.5-2.0 times from basic APTT. When the patient was about to be operated on, UFH was stopped 6 hours before surgery and resumed 12 hours after surgery. Warfarin was given one day postoperatively. Patients were adjusted to the dose of UFH according to the target. This patient had no thromboembolic events or bleeding before, during, or after surgery. The patient was allowed to be an outpatient and was given home therapy with Warfarin 5 mg at night. Results: We report a case of a 26-year-old female patient with a mechanical mitral valve who was going to undergo elective SCTP surgery and an IUD insertion. Patients at high risk of thrombo¬embolism due to surgery with a high risk of bleeding. Bridging therapy was performed using UFH. In the perioperative period, the patient did not experience thromboembolic events, and bleeding before, during, and after surgery could be well controlled. Conclusion: Perioperative management of patients with mechanical heart valves must be done carefully. Interruption of oral anticoagulants should be carefully considered considering the risk of thromboembolism and bleeding during the perioperative period. Guidelines recommend that in patients with mechanical heart valves, anticoagulation interruption for minor surgeries is avoided. Whereas in patients with major surgery, it is necessary to do bridging therapy with fast-acting anticoagulants such as UFH or LMWH. Keywords: mechanical heart valve, anticoagulant interruption, perioperative, bridging therapy Correspondence: Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University / Dr. Moewardi Hospital. Jl. Kol. Sutarto 132, Surakarta 57126, Central Java, Indonesia. Email: trisulo.wasyanto@staff.uns.ac.id. ORCID ID: 0000-0001-9900-0497. Mobile: +62811294225.
Conservative Management for Anterior STEMI Complicated by Ventricular Septal Rupture Nanda Eka Sri Sejati; Habibie Arianto; Irnizarifka
Cermin Dunia Kedokteran Vol 46 No 3 (2019): Nutrisi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v46i3.498

Abstract

Ventricular septal rupture is a rare complication of acute myocardial infarction but with a very high mortality, most often caused by severe hemodynamic failure. Conservative treatment is very inefficient with over 90% mortality rate; surgery is recommended as definitive treatment. A case of 67-year-old woman with chest pain since 1 day accompanied by shortness of breath and diaphoresis. Cardiac auscultation showed a 3/6 systolic murmur without thrill. ST elevation at the anterior lead was found in ECG. Echocardiography detected a rupture in interventricular septal with left-to-right shunt. The patient was diagnosed with anterior ST elevation myocardial infarction (STEMI) complicated by ventricular septal rupture. A conservative management was given without intra-aortic balloon pump placement and surgical operation due to patient’s rejection. One month post treatment, the patient exhibited a relatively stable hemodynamic with moderate to severe activity limitation. Ruptur septum ventrikel merupakan komplikasi infark miokard akut yang jarang, namun mortalitasnya sangat tinggi, paling sering karena kegagalan hemodinamik berat. Penanganan konservatif sangat tidak efisien dengan tingkat kematian lebih dari 90 %; intervensi bedah direkomendasikan menjadi tatalaksana definitif. Seorang wanita 67 tahun mengeluh nyeri dada sejak 1 hari disertai sesak nafas dan diaforesis. Auskultasi jantung menunjukkan bising sistolik 3/6 tanpa thrill. EKG mendapatkan elevasi segmen ST di sadapan anterior. Pada ekokardiografi ditemukan ruptur septum ventrikel dengan left-to-right shunt. Pasien didiagnosis infark miokard akut elevasi ST anterior dengan ruptur septum ventrikel. Manajemen konservatif tanpa pemasangan intra-aortic balloon pump ataupun tindakan operatif karena pasien menolak. Satu bulan pasca-perawatan, hemodinamik relatif stabil dengan keterbatasan aktivitas sedang-berat.
Zero-fluoroscopy versus fluoroscopy-guided catheter ablation in ventricular arrhythmia: A systematic review and meta-analysis Irnizarifka, Irnizarifka; Tristan, Christopher D.; Wijayanto, Matthew A.; Myrtha, Risalina; Modesty, Kyra; Rahma, Annisa A.; Budiono, Enrico A.; Rahman, Awalil R. K.; Hamka, Muhammad Farid; Ilyas, Muhana F.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narraj.v5i2.2094

Abstract

Catheter ablation has been the go-to treatment for ventricular arrhythmia, with traditional fluoroscopy-guided and non-zero fluoroscopy (NZF) catheter ablation posing high radiation risk for operators and patients. Zero-fluoroscopy technique offers elimination of radiation risk; however, its efficacy and safety in ventricular arrhythmia patients are not well explored. The aim of this study was to systematically evaluate the effectiveness, safety, and feasibility of zero-fluoroscopy ablation on ventricular arrhythmia patients. This study only included relevant studies comparing zero-fluoroscopy and NZF in ventricular arrhythmia ablation that were identified from Scopus, PubMed, and ScienceDirect (up to June 20, 2024). The quality of the study was assessed using the ROBINS-I tool, and the meta-analysis was conducted using a random-effect model. Out of 383 studies found, nine cohort studies were included with 1.408 patients. There was no significant difference in the acute procedural success rate of the zero-fluoroscopy and NZF (relative risk: 1.01; 95%CI: 0.95–1.07; p=0.69), with a similar recurrence rate (p=0.88; for four studies; n=374), and comparable procedural time (mean difference: -19.22 minutes; 95%CI: -41.16–2.72; p=0.09). Adverse events such as pericardial effusion, pseudoaneurysm, and hematoma were similar between zero-fluoroscopy and NZF. Overall, zero-fluoroscopy catheter ablation has demonstrated non-inferiority as a treatment option for ventricular arrhythmia ablation. As zero-fluoroscopy eliminates radiation risk without compromising procedural efficacy, zero-fluoroscopy has the potential to become a widely adopted approach for catheter ablation in ventricular arrhythmia.
Co-Authors Ahmad Yasa, Ahmad Anggraini, Nutria Aprila Aqmarina Indah Arifianto, Habibie Ario Soeryo Kuncoro Budiono, Enrico A. Chau, Titus Habibie Arianto Habibie Arifianto Haikal Haikal Hamka, Muhammad Farid Ilyas, Muhana F. Manoefris Kasim Modesty, Kyra Myrtha, Risalina Nanda Eka Sri Sejati Nuraini, Yulianna Cahya Praditya Virza Ramadhan Prameswari, Hawani Sasmaya Rahma, Annisa A. Rahman, Awalil R. K. Simangunsong, Robby Martin Sony Hilal Wicaksono Tristan, Christopher D. Vireza Pratama Wasyanto, Trisulo Wijayanto, Matthew A. Yudhistira, Yoga