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UJI AKTIVITAS ANTIDIARE EKSTRAK ETANOL DAUN MATOA (Pometia pinnata) PADA MENCIT JANTAN Moerfiah Moerfiah; Ihat Ismawat; Triastinurmiatiningsih Triastinurmiatiningsih
Gunung Djati Conference Series Vol. 18 (2023): Prosiding Seminar Nasional Biologi (SEMABIO) Tahun 2022
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1083.164 KB)

Abstract

Matoa empirically has been used by the people of Indonesia as an antidiarrheal drug. The phytochemical test of matoa leaves contains phenolic and flavonoid which are efficacious as astringents and can stop diarrhea. The purpose of this study was to determine the effectiveness of the ethanolic extract of matoa leaves as an antidiarrheal in male mice. Twenty-five male mice were divided into 5 groups with each treatment having 5 replications. The treatment doses of ethanol extract of matoa leaves tested were: dose I (3mg/20 g BW), dose II (6 mg/20g BW), dose III (12mg/20 g BW) and positive control (loperamide 0.02 mg/20 g BW) and negative control (1% CMC suspension). The results obtained in this study that matoa leaves are effective as antidiarrheal, a dose of 12 mg/20g BW is the most effective and equivalent to positive control (loperamide 0.02 mg/20g BW).
Effectiveness Of Tajin Water (Rice-Water) As A Coupling Food To Improve Weight Board (Mus Musculus) Lusi Agus Setiani; Moerfiah Moerfiah; Putri Kemala Dewi
Journal of Science Innovare Vol 6, No 1 (2023): Journal of Science Innovare, Volume 06 Number 01 2023
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jsi.v6i1.7747

Abstract

Malnutrition can occur on children of aged 6 to 24 months. During this period, there is generally a change in needs from exclusive breastfeeding to complementary foods and additional food can also be added. Starch water which is a springy white liquid obtained from rice that is cooked with the nutritional content of energy, protein, fat, carbohydrates, calcium, iron, vitamin B1. This study aims to test the effectiveness, determine the best concentration and determine the influence of the length time from using of starch water as an additional complementary food to increase body weight of male mice (Mus musculus) for 21 days by oral treatment. The experiment and method that used in this experiment is was pretest-posttest control group design. Starch water is obtained by means of rice being heated with 1200 mL of water for ± 30 minutes, filtering and extracting is obtained. Starch water concentrations commonly used empirically tested in this study are concentrations of 12.5%; 18.7%; 25%. The 25% concentration is the concentration that has an effective effect on body weight of mice with the results (21.87 ± 4.29) which differ 2.38% from the positive control results (24.25 ± 8.93).