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Dewi Elianora, Dewi

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Author-ID : 596876

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Activities test of Mahkota Dewa (Phaleria macrocarpa) leaves extract against Candida albicans of HIV/AIDS patients Elianora, Dewi; B., Busman; Amrilya, Yeri
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March
Publisher : Faculty of Dentistry Universitas Padjadjaran, Indonesia

ABSTRACTIntroduction: Candida albicans is a local commensal flora of the oral cavity, with opportunistic nature andÂ often causes oral candidiasis in HIV/AIDS patients. Since long time, Mahkota Dewa (Phaleria macrocarpa)Â known of having efficacy treat various disease traditionally. The purpose of this study was to determineÂ the activity test of Phaleria macrocarpa leaves extract against Candida albicans from HIV/AIDS patients.Â Methods: Experimental laboratory with samples colonies of the Candida albicans fungus obtained fromÂ patients with HIV/AIDS at Dr. M. Djamil General Hospital Padang. Research conducted during January-March 2016 in Microbiology and Chemistry Laboratory of Kopertis Region X, Microbiology Laboratory ofÂ Dr. M. Djamil General Hospital, and Microbiology Laboratory of Siti Rahmah Islamic Hospital, Padang,Â West Sumatra. Data analyzed using the Kruskal-Wallis test. Results: The concentration of the PhaleriaÂ Macrocarpa leaves extract used in this study was 10, 20, 40 and 80%. Inhibition zone average valueÂ obtained 0,00 mm, means no inhibition zone, 9.217 mm and 18.017 mm with sig = 0.000 <0.05. Conclusion:Â The higher level of the Phaleria macrocarpa leaves extract concentration, the higher inhibition zoneÂ diameter against Candida albicans, with the highest in concentration 80%.Keywords: Mahkota Dewa (Phaleria macrocarpa) leaves extract, Candida albicans, HIV/AIDS

Activities test of Mahkota Dewa (Phaleria macrocarpa) leaves extract against Candida albicans of HIV/AIDS patients Elianora, Dewi; B., Busman; Amrilya, Yeri
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March 2017
Publisher : Universitas Padjadjaran

ABSTRACTIntroduction: Candida albicans is a local commensal flora of the oral cavity, with opportunistic nature and often causes oral candidiasis in HIV/AIDS patients. Since long time, Mahkota Dewa (Phaleria macrocarpa) known of having efficacy treat various disease traditionally. The purpose of this study was to determine the activity test of Phaleria macrocarpa leaves extract against Candida albicans from HIV/AIDS patients. Methods: Experimental laboratory with samples colonies of the Candida albicans fungus obtained from patients with HIV/AIDS at Dr. M. Djamil General Hospital Padang. Research conducted during January-March 2016 in Microbiology and Chemistry Laboratory of Kopertis Region X, Microbiology Laboratory of Dr. M. Djamil General Hospital, and Microbiology Laboratory of Siti Rahmah Islamic Hospital, Padang, West Sumatra. Data analyzed using the Kruskal-Wallis test. Results: The concentration of the Phaleria Macrocarpa leaves extract used in this study was 10, 20, 40 and 80%. Inhibition zone average value obtained 0,00 mm, means no inhibition zone, 9.217 mm and 18.017 mm with sig = 0.000 <0.05. Conclusion: The higher level of the Phaleria macrocarpa leaves extract concentration, the higher inhibition zone diameter against Candida albicans, with the highest in concentration 80%.Keywords: Mahkota Dewa (Phaleria macrocarpa) leaves extract, Candida albicans, HIV/AIDS

Comparison of the salivary bacterial colonies number and pH value in early and non-early childhood caries due to consuming infant formula using the nursing bottle Elianora, Dewi; Busman, Busman; Ayusa, Febri Mona
Padjadjaran Journal of Dentistry Vol 31, No 3 (2019): November 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no3.23791

Introduction: Saliva plays a vital role in the caries process. The critical function of saliva is to defence against caries. A decrease in the saliva secretion speed can be followed by an increase in the number of bacterial colonies. This study was aimed to determine the comparison of salivary bacteria colonies number and salivary pH on early and non-early childhood caries in children who consumed infant formula using the nursing bottle. Methods: This research was pure experimental research with cross-sectional approach. Fifteen children with ECC and fifteen children with non-ECC aged 2-4 years on Early Childhood Education Programs (PAUD) of Padang, West Sumatera, were included in this study. Thirty subjects were participated in this study and asked to collect saliva into a sterile container provided. Statistical analysis used was independent sample t-test. Results: There was a significant difference in the salivary pH and the number of salivary bacterial colonies on early childhood caries and non-early childhood caries children after consuming infant formula with the nursing bottle (p < 0.05). The number of salivary bacteria colony on the infant with early childhood caries was higher with an average of 407.2 x 10-4/ml, whereas in infant non-early childhood caries was lower with an average of 125.5 x 10-4/ml. The salivary pH on infants with early childhood caries was acid with an average of 6.2, and in infants with non-early childhood caries was normal with an average of 6.9. Conclusion: There is a difference in the number of salivary bacterial colonies in infants with early childhood caries and non-early caries after consuming infant formula using the nursing bottle.Keywords: Early childhood caries, non-early childhood caries, salivary bacterial colonies, salivary pH

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