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All Journal Folia Medica Indonesiana Majalah Kesehatan FKUB Ina Kidney Cermin Dunia Kedokteran
Jefri Pratama Susanto, Jefri Pratama
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Other

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Journal : Folia Medica Indonesiana

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Review article: THE ROLE OF ELTROMBOPAG AND ROMIPLOSTIM AS THE THROMBOPOIETIN RECEPTOR AGONIST (TPO-RA) IN TREATMENT OF IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP): WHAT IS TPO-RA, WHEN TPO-RA IS USED AND HOW TO TAKE TPO-RA? Susanto, Jefri Pratama
Folia Medica Indonesiana Vol. 51 No. 3 (2015): July - September 2015
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.168 KB) | DOI: 10.20473/fmi.v51i3.2840

Abstract

Idiopathic thrombocytopenic purpura is a autoimmune disease characterized thrombocytopenia casued by excessive platelet destruction. However, both platelet destruction and reduced thrombopoietin level are occurred in some cases. Therefore, new management of ITP is emerged which target is to increase platelet production rate via eltrombopag or romiplostim as the thrombopoietin receptor agonist (TPO-RA). Eltrombopag is given orally while romiplostim is given subcutaneously or intravenously and dose adjustment is depend on platelet count. Both eltrombopag and romiplostim is indicated in minimal response glucocorticoid or intravenous immunoglobulin or splenetomy treatment.
Co-Authors ACHMAD RIFAI Heri Sutanto hermanto, djoko heri Indiastari, Dewi Niniek Budiarti B Sri Soenarti