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Medication Adherence, Glycemic Control and Quality of Life in Patients with Type 2 Diabetes Mellitus: a cross-sectional study Delila Eliza; Nadia Farhanah Syafhan; Retnosari Andrajati; Sri Wulandah Fitriani
Jurnal Sains Farmasi & Klinis Vol 10, No 1 (2023): J Sains Farm Klin 10(1), April 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.1.21-27.2023

Abstract

Medication adherence is important in controlling blood sugar levels (HbA1c) in patients with Diabetes Mellitus (DM). Studies on the relationship between medication adherence and blood sugar control on the quality of life (QoL) in Type 2 DM patients are limited in Indonesia. This study aims to assess the relation between medication adherence with blood sugar control and the quality of life of Type 2 DM patients. This study used a cross-sectional design conducted at Universitas Indonesia Hospital. It used Medication Adherence questionnaires and EuroQoL 5D-5L questionnaires to assess patients’ medication adherence and quality of life. This study involved a total of 74 Type 2 DM patients with an average age of 57 ± 10.74 years. Medication adherence with good blood sugar control (HbA1c <7%) showed a significant relationship (p-value <0.05) with COR values of 3.74 (1.21 - 11.6) compared to non-adherent patients. But not on the QoL Index and VAS (Visual Analog Scale) values, where the value is lower in patients with high adherence and good blood sugar control. Factor asscociated with blood sugar controlled were comorbidites and medication adhrence while factor that associated with quality of life were comorbidities, ages, education and employment status
Study of Potential Drug Interactions in COVID-19 Patients with Comorbid Type 2 Diabetes Mellitus at The General Hospital in South Tangerang City, Period 2021ral Hospital in South Tangerang City Nurmeilis; Yusroh Umami; Nurhaida; Delila Eliza
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 7 No. 2 (2025)
Publisher : Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v7i2.39167

Abstract

Diabetes mellitus is one of the common comorbidities found in COVID-19 patients. The use of large amounts of medication (polypharmacy) in COVID-19 patients with comorbid diabetes mellitus can increase the possibility of drug interactions. The study aimed to determine the potential drug-drug interactions and it is the relationship with clinical outcomes in COVID-19 patients with comorbid type 2 diabetes mellitus at the General Hospital in South Tangerang City. The study was a retrospective study conducted in the hospital by using patients medical records from January-December 2021. Potential drug-drug interactions were analyzed by using the software, Medscape, and Drugs.com. The 97 patients met the inclusion and exclusion criteria. The results of the study were found in 40 patients who experience drug interactions with COVID-19 drugs and antidiabetics (58.2%), the majority of them are in moderate severity degree (78.5%), major severity degree (21.5%), with pharmacodynamic mechanism (100%). There is no significant relationship between drug interactions and clinical outcomes of patients (P>0.05). The interactions found were all pharmacodynamic, although there was no significant relationship to clinical outcomes, therapeutic monitoring was still required.
Peran Potensial Farmasis dalam Optimalisasi Terapi Pasien Long COVID-19: Tinjauan Literatur Rizki Oktarini; Reza Rahmawati; Delila Eliza
Jurnal Vokasi Kesehatan Vol 4 No 2 (2025)
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/juvokes.v4i2.1407

Abstract

Long COVID-19 merupakan sindrom pasca infeksi akut SARS-CoV-2 yang ditandai dengan gejala yang menetap selama berminggu-minggu atau bahkan berbulan-bulan setelah fase infeksi akut berakhir. Gejala yang umum meliputi kelelahan kronis, gangguan tidur, nyeri otot atau sendi, gangguan pernapasan, serta disfungsi kognitif seperti kesulitan berkonsentrasi dan kabut otak. Kondisi ini memberikan tantangan baru dalam sistem pelayanan kesehatan, terutama dalam aspek manajemen jangka panjang. Meskipun demikian, peran farmasis klinis dalam tatalaksana pasien Long COVID-19 masih belum banyak dieksplorasi secara sistematis dalam berbagai studi. Artikel ini bertujuan untuk meninjau peran strategis farmasis dalam pemantauan farmakoterapi, pemberian edukasi kepada pasien, serta keterlibatan dalam tim kolaboratif interprofesional guna meningkatkan luaran klinis dan kualitas hidup pasien. Metode narrative review digunakan dengan menelaah berbagai literatur ilmiah dari tahun 2020 hingga 2024. Berdasarkan hasil tinjauan, keterlibatan farmasis terbukti berkontribusi terhadap pengurangan efek samping obat, peningkatan kepatuhan pasien terhadap regimen terapi, serta mendukung proses rehabilitasi secara menyeluruh. Dengan demikian, peran farmasis menjadi semakin penting dan perlu diintegrasikan dalam sistem layanan kesehatan untuk mendukung pemulihan pasien Long COVID-19 secara berkelanjutan.