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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Dikdimas : Jurnal Pengabdian Kepada Masyarakat
Muhammad Hidyatullah
Universitas Borneo Lestari
Agriculture, Biological Sciences & Forestry Humanities Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Social Sciences Other

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Optimization Method and Stability Test to Determinate Luteolin, Quercetin, Apigenin, and Sinensetin Levels in Herbal Medicines Using TLC-Densitometry Muhammad Hidayatullah; Mochammad Yuwono; Riesta Primaharinastiti
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 9 No. 3 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v9i32022.235-241

Abstract

Background: Nephrolithiasis is a condition in which there are one or more kidney stones in the pelvis or calyces. Luteolin, quercetin, apigenin, and sinensetin are marker compounds in the extracts of Plantago major, Sonchus arvensis, Strobilanthes crispus and Orthosiphon stamineus which have nephrolithiasis activity. To control the quality of herbal medicines, a TLC-Densitometry method was developed in this study using luteolin, quercetin, apigenin, and sinensetin as phytochemical markers. Objective: The present work aimed to develop optimal conditions for analyzing luteolin, quercetin, apigenin, and sinensetin. Methods: Determination of optimal conditions for analysis is carried out by determining the composition of the mobile phase, chamber saturation time, and analysis wavelength. Silica gel 60 F254 was used as the stationary phase. Stability tests were carried out by analyzing standards and samples at 0, 4, 8, and 24 hours. Results: The best separation that produces symmetrical peaks of herbal medicine was achieved under isocratic conditions using the composition of the mobile phase chloroform : acetone: dichloromethane : acetonitrile : formic acid (6 : 2: 2 : 0,05 : 0.05 v/v/v/v/ v) with a wavelength of 335 nm with a saturation time of 30 minutes. Conclusion: In this study, the optimal conditions for the analysis of luteolin, quercetin, apigenin, and sinensetin. Luteolin, quercetin, apigenin, and sinensetin are unstable during 8 hours of storage. Therefore, standard solutions and samples must be made fresh to maintain stability.
Education on Giving Leaflets and The Potential of Karamunting Leaves (Rhodomyrtus Tomentosa) Herbal Efficacious in Society M. Andi Chandra; Muhammad Hidyatullah
DIKDIMAS : Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2023): DIKDIMAS : JURNAL PENGABDIAN KEPADA MASYARAKAT  VOL 2 NO 1 APRIL 2023
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.821 KB) | DOI: 10.58723/dikdimas.v2i1.80

Abstract

Coronavirus disease (COVID-19) is spreading rapidly throughout the world including Indonesia. The use of herbal medicinal plants has increased since the Corona Virus Disease (COVID-19) pandemic, one of which is karamunting leaves. The methods used include: Field observations, we recorded the number of residents, their work and the plants that grow in the yard so that they can provide education to the community, especially in the North Landasan Ulin Village, Lianganggang District, Banjarbaru City. The results of the initial observation activities were carried out to look for problems in the community, the problems encountered by the community service team were the lack of public knowledge about plants that have the potential for traditional medicinal properties. Planting in the yard of the house has a characteristic as an herbal medicine. The conclusion from this activity was that education and giving leaflets for karamunting plants received a positive response from the community, after being given materials and leaflets as well as interactive discussions, the community realized the importance of using herbal medicines as an alternative treatment and increasing body immunity.
Co-Authors M. Andi Chandra Mochammad Yuwono Rahmi Hidayati Rahmi Muthia Riesta Primaharinastiti