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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Jhoti Sumitra
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Health Professions Medicine & Pharmacology Nursing Public Health

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SEMINAR FORMULASI SEDIAAN PASTA GIGI EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) DAN UJI EFEKTIVITAS TERHADAP BAKTERI Streptococcus mutans Asvia Rahayu; Sa'adah Siregar; Jhoti Sumitra; Annisa Paradita
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 1 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (475.146 KB) | DOI: 10.35451/jpk.v1i1.654

Abstract

Fragrant pandanus (Pandanus amaryllifolius Roxb.) is the only plant in the Family Pandanaceae that has fragrant leaves. This study aims to find out if pandan leaf extract is fragrant. can be formulated into a stable toothpaste gel preparation and has the cause of dental plaque. The test material used pandan leaf extract is fragrant for concentrations of 2%, 3% and 5%. The results of the evaluation of preparations in the form of organoleptic tests, homogeneity, pH, spreadability test, adhesion test, viscosity and frezee-thaw cycling of each formula did not undergo significant changes from week 0 to week 3 which indicates that the preparation has good stability. The data is obtained with results indicating a significant difference between formula 1, formula 2 and formula 3. It is necessary to make formulations using active substances from the partition of fragrant pandan leaf extract (Pandanus amaryllifolius Roxb.)
TEST OF THE INHIBITOR EFFECTIVENESS OF THE COMBINATION OF ETHANOL EXTRACT OF LEMON LEAVES (Cymbopogon citratus) AND GREEN BETEL LEAF (Piper betle L.) AGAINST Staphylococcus aureus BACTERIA Octora, Debi Dinha; Samuel Marpaung; Jhoti Sumitra
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1860

Abstract

The discovery of natural substances has the potential for applications in the development of pharmaceuticals or natural alternatives to combat bacterial infections. Green betel leaves (Piper betle L.) and lemongrass stems (Cymbopogon citratus) may aid in treating infections due to their specific strength in bacteria eradication. Staphylococcus aureus is one of the pathogenic bacteria types that can cause serious infections and skin disorders under conducive conditions, such as acne and boils. The aim of this study is to determine the antibacterial activity using the maceration and disk diffusion methods on lemongrass stem and green betel leaf extracts against Staphylococcus aureus bacteria. The research conducted is qualitative in nature and aims to assess the inhibitory effect of the combination of ethanol extracts from lemongrass and green betel leaves at various concentrations on the growth of Staphylococcus aureus bacteria. Different concentrations of green betel leaf and lemongrass stem extracts were also tested to determine the most effective concentration in inhibiting bacterial growth. The results demonstrate that specific concentrations of green betel leaf and lemongrass stem extracts have a stronger antibacterial effect compared to other concentrations. The combination of ethanol extracts from lemongrass stems and green betel leaves can inhibit the growth of Staphylococcus aureus bacteria using the paper disk method, with inhibition zone diameters observed for each extract concentration and the positive control Ciprofloxacin, which had a diameter of 25.92 mm. The best concentration formula for the combination of lemongrass stem (Cymbopogon citratus) and green betel leaf (Piper betle L.) ethanol extracts is at 15% concentration, resulting in an average diameter of 18.90 mm. Keywords: Antibacterial, Piper betle L., Cymbopogon citratus, Staphylococcus aureus
Co-Authors Annisa Paradita Asvia Rahayu Octora, Debi Dinha Sa'adah Siregar Samuel Marpaung