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All Journal INDRA: Jurnal Pengabdian kepada Masyarakat Parapemikir Jurnal Ilmiah Farmasi Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Rahmawati Raising
Stikes Bhakti Husada Mulia Madiun
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health

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Pengelolaan hasil tanaman obat keluarga (TOGA) jamu instan jahe merah (Zingiber officinale var. rubrum) Rahmawati Raising; Novi Ayuwardani; Oktaviarika Dewi Hermawatiningsih; Yetti Hariningsih; Vevi Maritha; Tika Indrasari
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v4i1.176

Abstract

Community participation in health development with TOGA (Family Medicinal Plants) or commonly referred to as a live pharmacy, in order to meet the family's need for medicines. Cultivation of medicinal plants for families (TOGA) can stimulate small and medium enterprises in the field of herbal medicine. Red ginger is one of the herbal plants that has been widely known as a health support product by the public because empirically it has many health benefits such as anti-inflammatory, reducing nausea and immunomodulatory with few side effects. Therefore, training is needed to improve the skills of PKK team in making Red Ginger Instant herbal products, the target of this community service activity is PKK team, using presentation methods, demonstrations on how to make red ginger instant herbal products. The results of this community service activity increase understanding of making instant herbal medicine
Pengaruh Polimorfisme P2Y12 Pada Penggunaan Antiplatelet Terhadap Kejadian Stroke Berulang oktaviarika dewi hermawatiningsih; Rahmawati Raising
Parapemikir : Jurnal Ilmiah Farmasi Vol 12, No 1 (2023): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v12i1.4414

Abstract

Stroke merupakan keadaan defisit neurologik secara fokal dan global. Salah satu pengobatan yang digunakan adalah antiplatelet seperti clopidogrel yang dapat menghambat pembentukan trombus yang bisa menurunkan angka kematian. Dalam perkembangan pengobatan, terdapat variasi respon pasien terhadap terapi clopidogrel. Variasi respon tersebut seperti polimorfisme reseptor P2Y12 yang berdampak pada farmakokinetik dan farmakodinamil dari clopidogrel. Tujuan dari penelitian ini adalah untuk menyetahui pengaruh kejadian polimorfisme reseptor P2Y12 terhadap kejadian stroke berulang. Metode yang digunakan dalam peneltian ini adalah metode Polymerase Chain Reaction (PCR) yaitu dengan cara pemeriksaan polimorfisme genetik P2Y12 dan dilakukan pemantauan setiap bulan untuk mengetahui kejadian stroke berulang. Hasil yang diperoleh dari penelitian ini adalah dari 20 sampel diperoleh jenis polimorfime P2Y12 homozygot (wild type), untuk kejadian stroke berulang diperoleh 4 sampel yang mengalami kejadian stroke berulang, dan analisis pengaruh polimorfisme P2Y12 terhadap kejadian stroke berulang diperoleh nilai signifikansi 0,05, sehingga dalam penelitian ini dapat disimpulkan bahwa tidak terdapat pengaruh antara polimorfisme P2Y12 terhadap kejadian stroke berulang.
Uji Efektivitas Antiinflamasi Kombinasi Ekstrak Herba Seledri (Apium Graveolens L.) Dan Daun Binahong (Anredera Cordifolia (Ten.) Steenis) Pada Tikus Putih Karina Wulan Sari; Rahmawati Raising; Novi Ayuwardhani
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 3 No. 2 (2023): Juli : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v3i2.1666

Abstract

Inflammation is a protective response that is intended to eliminate the initial cause cell injury and cell discard and necrotic tissue caused by cell damage. Plants suspected of having anti-inflammatory properties as is Herba Celery (Apium graveolens L.) which included family Apiaceae and leaves Binahong (Anredera cordifolia (Ten.) Steenis) are included in the family basellaceae. Which act as antiinflammatory herbs binahong celery and leaves are flavonoids. This study aims to determine the effect of anti-inflammatory herb extract combination Celery (Apium graveolens L.) and leaves Binahong (Anredera cordifolia (Ten.) Steenis) against a white male rats. Herbal extract and leaf celery binahong extracted using 96% ethanol by maceration method. Animal test used was a white male rats as much as 25 animals with body weight of 100-300 grams. The test animals were divided into 5 groups: negative control group (CMC 1%), the positive control group (Diclofenac Sodium 50 mg), group combination herbal extracts celery and leaves binahong with a dose of 200 mg / kg: 200 mg / kg, 100 mg / kg: 300 mg / kg, 300 mg, kg: 100 mg / kg. Treatment 1 hour before the feet of mice induced by subplantar karagenin on the rear left foot white male rats. Edema volume measurements on the soles of mice were observed every 1 hour for 5 hours. The results showed a combination of herbal extracts and leaf celery binahong show stable results, where the hour-3 increased volumes continued in the hours 4th and 5th. Results per cent udema on a combination of herbal extracts and leaf celery binahong ie 49.13%, 44.66% and 45.92%. The average volume is used to calculate the percent edema inflammation, inflammation percent results obtained to calculate the percent inhibition.
Co-Authors Hariningsih, Yetti Hermawatiningsih, Oktaviarika Dewi Karina Wulan Sari Novi Ayuwardani Novi Ayuwardhani Tika Indrasari Vevi Maritha