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All Journal Majalah Kedokteran Sriwijaya Bioscientia Medicina : Journal of Biomedicine and Translational Research International Journal of Islamic and Complementary Medicine Ophthalmologica Indonesiana
Elza Iskandar, Elza
Department Of Ophthalmology, Faculty Of Medicine, Sriwijaya University Mohammad Hoesin Hospital, Palembang, South Sumatera
Religion Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Prevalensi Entropion di RSUP Dr. Mohammad Hoesin Palembang Atifatur Rachmania; Elza Iskandar; Yan Effendi Hasyim
Majalah Kedokteran Sriwijaya Vol 46, No 4 (2014): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v46i4.2721

Abstract

Entropion adalah kelainan palpebra dimana terjadi pelipatan dari tepi palpebra ke arah dalam bola mata sehingga akan menyebabkan gesekan dari tepi palpebra, bulu mata, dan kulit palpebra terhadap kornea dan akan menimbulkan gejala iritasi, keratitis mikroba, ulserasi kornea hingga terjadi kehilangan penglihatan. Belum ada data mengenai prevalensi dan karakteristik penderita entropion di Poliklinik Mata RSUP Dr. Mohammad Hoesin Palembang.Penelitian ini bertujuan untuk mendapatkan  prevalensi dan karakteristik penderita entropion di Poliklinik Mata RSUP Dr. Mohammad Hoesin Palembang.Jenis penelitian yang digunakan adalah penelitian deskriptif observasional dengan pendekatan potong lintang dengan menggunakan data sekunder dari rekam medis.Dari Januari 2010-Desember 2012 didapatkan 12 kasus entropion dengan prevalensi tiap tahunnya berturut-turut sebesar 0,031%, 0,079%, dan 0,134%. Kasus entropion pada perempuan (58,3%) dan pada laki-laki (41,7%). Dari 12 pasien entropion, 6 pasien entropion involusional (50%), 5 pasien entropion sikatrik (41,7%), dan 1 pasien entropion kongenital (8,3%). Terjadi peningkatan prevalensi entropion dari tahun 2010 hingga 2012 walaupun prevalensinya <1 %. Entropion lebih sering ditemukan pada perempuan dibandingkan laki-laki. Klasifikasi entropion yang paling sering ditemukan adalah entropion involusional.
CENTELLA ASIATICA EXTRACT EFFECT ON POSTOPERATIVE WOUND HEALING Elza Iskandar; Theodorus Theodorus; Anang Tribowo; Riani Erna; Fatimah Syakirah
International Journal of Islamic and Complementary Medicine Vol. 2 No. 2 (2021): International Journal Islamic Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.052 KB) | DOI: 10.55116/IJIM.V1I1.28

Abstract

Wound healing is a complex process that is divided into four phases, namely the hemostasis, inflammation, proliferation, and tissue remodeling phase. Centella asiatica is a widely used and very popular traditional plant in the field of health for a long time. Various in vitro and in vivo studies have proven the efficacy of Centella asiatica extract in the wound healing process. This literature review uses literature search methods from Pubmed, Science Direct, and Cochrane Library with keywords Centella asiatica, wound healing, surgery. This study aims to study the effects of Centella asiatica extract on postoperative wound healing.
The Comparison of S100 A8/A9 Protein Receptor Expression between Progressive and Non-Progressive Pterygium Cerah Puspinarti; Elza Iskandar; Riani Erna; Wresnindyatsih Wresnindyatsih; Erial Bahar
Majalah Oftalmologi Indonesia Vol 41 No 3 (2015): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v41i3.53

Abstract

Background: S100 A8/A9 protein suggest have an activity at inflammation pathway caused fibroblast proliferation which is support the patofisiology teori of pterygium. Methods: This research is a cross sectional study consists of 21 subject who suffered primary nasal or temporal pterygium. All subject divided into 2 grup, progressive dan non progressive pterygium with this following criteria: length of pterygium at the cornea, diameter ilots de Fuch, thickness of corpus compare with apex dan hiperemia of pterygium. The tissue of pterygium after excised were examined through histopatology and immunohistochemical with HE and reagent Mab 27E10 staining to see S100 A8/A9 protein reseptor expression. And than we calculate between staining cell and intencity of the brown-colour of reseptor that call staining Index to see the trend to proggressive pterygium. Results: From 21 subject of study, amount of 11 subject (52,38%) progressive pterygium and 10 subject non progressive pterygium (47,62%). We found S100 A8/A9 protein reseptor expression at proggressive group were higher than non progressive group. Cut off point in staining index is 25 that show the pterygium has trend to be proggresive at that point or more. Histopatology examination there are strong correlation progresifity pterygium with squamous epithel prolifertion, cell inflamation, and vascular proliferation. Conclusion: There is a significant differentiate in S100 A8/A9 protein receptor expression between progressive and non progressive pterygium. Keywords: S100 A8/A9 protein, progressive pterygium, immunohistochemical
Intralesional oxytetracycline injection for treatment of lower eyelid festoons Intan Ramli; Elza Iskandar; Theodorus Theodorus
Majalah Oftalmologi Indonesia Vol 43 No 1 (2017): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v43i1.144

Abstract

Introduction : Festoons of the lower eyelids are excess of loose skin and lower orbicular muscles that hang from the cantal to the cantal. Some treatment options may improve the appearance of the festoons. Oxytetracycline has a function to block metalloproteinase matrix so that serve to form structural proteins and building tissues and improving collagen conditions for skin elasticity. Objective to determine the efficacy of oxytetracycline intralesional injection for treatment of lower eyelid festoons on patients in Palembang, South Sumatra. Method : Clinical Trial without comparison of patients undergoing oxytetracycline 2% injection of lower eyelidfestoons was conducted at RSMH Eye Clinic Palembang from November 2016 un­ til March 2017. There were 32 samples of lower eyelid festoons on patients aged over 35 years old who met inclusion and exclusion criteria. Frequency and data sharing. Data is calcu­ lated with AutoCAD program and analyzed using the Paired T Test and the Wilcoxon Test Results : Thirty two samples of lower eyelid festoons on patients aged ranges 41 to 69 years. Follow up was 4 weeks. Patients received 0,3cc of oxytetracyline 2% intralesion. There were a high differences of festoons at preinjection and 2 weeks after injections of 0.074cm (p=0,000) and preinjection at 4 weeks after injection of 0.142cm (p=0,000) There were a differences of festoons in length at preinjection and 2 weeks after injection of 0.053cm (p=0,000) and preinjection at 4 weeks after injection of 0.172cm (p=0,000). Conclusion : Intralesional oxytetracycline 2% injection was effective for treatment of lower eyelid festoons on patients in Palembang, South Sumatra.
Immunological Implications of Gold Weight Implantation for Lagophthalmos: A Systematic Review Iskandar, Elza; Krisna Murti; Irsan Saleh; Ramzi Amin
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 12 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i12.1138

Abstract

Background: Gold weight implantation is a well-established surgical intervention for lagophthalmos, a condition characterized by incomplete eyelid closure. While generally safe and effective, gold implants can elicit immune responses, potentially leading to complications. This systematic review aims to comprehensively evaluate the immunological implications of gold weight implantation in lagophthalmos treatment. Methods: A systematic search of PubMed and ScienceDirect databases was conducted, encompassing studies published from 2000 to June 2024. Keywords included "gold weight implant" and "gold implant AND eyelid." Studies reporting quantitative data on immune responses to gold implants were included. Data extracted included study design, patient demographics, implant characteristics, follow-up duration, complications, and long-term outcomes. Results: Thirteen studies met the inclusion criteria, encompassing a total of 340 patients (370 eyelids). Reported complications included hypersensitivity reactions (11.9%), lymphoma (0.6%), infection (1.2%), extrusion (8.1%), and nonspecific inflammatory reactions (4.3%). Hypersensitivity reactions were mediated by T-cell and B-cell responses, leading to chronic inflammation. Lymphoma cases highlighted the potential for chronic inflammation to trigger lymphoproliferative disorders. Infections were infrequent but could necessitate implant removal. Extrusion rates varied, influenced by implant size and placement. Nonspecific inflammatory reactions were observed, often requiring implant removal or steroid treatment. Conclusion: Gold weight implantation can trigger diverse immune responses, ranging from mild inflammation to severe hypersensitivity and lymphoma. Careful patient selection, meticulous surgical technique, and vigilant postoperative monitoring are crucial to minimize complications. Further research is warranted to elucidate the precise mechanisms underlying these immune responses and develop strategies for their prevention and management.
Co-Authors Anang Tribowo Atifatur Rachmania Cerah Puspinarti Erial Bahar Fatimah Syakirah Intan Ramli Irsan Saleh Krisna Murti Ramzi Amin, Ramzi Riani Erna Riani Erna Theodorus Theodorus Theodorus Theodorus Wresnindyatsih Wresnindyatsih Yan Effendi Hasyim