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Efektivitas COX-2 Inhibitor Sebagai Preemptive Analgesia pada Operasi Total Knee Arthoplasty Siriwa, Sultan Yosua; Suparto, Suparto; Ciulianto, Rudy
Jurnal MedScientiae Vol 3 No 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3247

Abstract

Post-operative pain, especially TKA procedures, is a problem that is often encountered. The use of adequate analgesics is the main treatment to reduce the side effects of pain, namely immobilization, decreased range of motion (ROM), increased risk of thromboembolism and decreased success rate of rehabilitation. Several previous studies reported the possibility of a significant therapeutic effect on the postoperative pain response by using preemptive analgesia methods with cyclooxygenase-2 inhibitors (COX-2 inhibitors). The aim of this study was to determine the effectiveness of COX-2 inhibitors using the preemptive analgesia method in total knee arthroplasty surgery through a literature study. Data searches were carried out on several electronic journal databases PubMed, ProQuest and Google Scholar, with the keywords "cyclooxygenase 2 inhibitors", "COX-2 inhibitor", "celecoxib", "valdecoxib", "rofecoxib", "etoricoxib", "non- steroidal anti-inflammatory drugs”, “preoperative analgesia”, and “total knee arthroplasty”. in 2013-2022. Overall, the study showed a significant response to the use of COX-2 inhibitors in preemptive analgesia methods to suppress the pain response at rest and during knee flexion after TKA when compared with the control group. The PA method with COX-2 inhibitors has also been proven to be successful in reducing the level of use of salvatory analgesics, which indirectly indicates that pain control has been successful. COX-2 inhibitors have been proven to be effective in reducing the pain response as a preemptive analgesia method in patients undergoing TKA procedures.
An Overview and The Factors Affecting Anaemia in Children Aged 6-24 Months at RSUD Tarakan Fitri, Aulia; Ciulianto, Rudy; Surjadjaja, Maya; Agilan, Danesh
Jurnal MedScientiae Vol. 1 No. 1 (2022): August
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v1i1.3096

Abstract

Anaemia is a clinical condition in which the erythrocyte level is below the normal value, causing oxygen insufficiency in body tissues. The purpose of this study was to determine the risk factors and the overview that affects the degree of anaemia in children aged 6 to 24 months in Tarakan Hospital. A cross-sectional design was used by analysing data from medical records retrospectively in the period January 2017-June 2018 and conducted interview sessions with parents or caregivers of patients using sample of 66 patients. The data evaluated included haemoglobin (Hb) levels, nutritional status, gestational age, consumption of type of milk for the first 6 months, and complementary feeding according to age using Kolmogorov Smirnov test. The highest prevalence of anaemia severity in Tarakan Hospital at the stated period was moderate anaemia of 47 people (71.2%). Distribution of severe anaemia incidence was 8 people (12.1%) and mild anaemia was 11 people (16.7%). Based on the test results, the obtained p value of risk factors for gestational age (0.759), nutritional status (0.999), consumption of the type of milk for the first 6 months (1,000) and complementary feeding according to age (1,000) where all p values> 0.05, that indicates no correlation statistically. The results of this study showed no correlation between risk factors and severity of anaemia statistically in children aged 6 months to 24 months in Tarakan Hospital.
Intervensi Keperawatan untuk Penguatan Otot pada Anak Ensefalitis : Literature Review Putri, Frischa Ananda; Cahya, Monica Dwi; Permaida, Permaida; Ciulianto, Rudy
Jurnal Pustaka Keperawatan (Pusat Akses kajian Keperawatan) Vol 5 No 1 (2026): Jurnal Pustaka Keperawatan
Publisher : Pustaka Galeri Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Encephalitis is an inflammatory condition of the brain parenchyma that often causes serious neurological disorders, as well as muscle weakness, motor dysfunction, impaired coordination, and decreased independence in children's daily activities. The broad clinical impact of encephalitis makes it not only an acute infection but also a condition with long-term implications for children's motor development and quality of life. Therefore, nursing interventions should focus on two main aspects: medical stabilization during the acute phase and structured rehabilitation during the recovery phase. This study aimed to evaluate the effectiveness of nursing interventions in improving muscle strength in children with encephalitis by reviewing the latest literature. This research employed a literature review approach, searching publications from 2020 to 2025 and identifying six articles that met the inclusion criteria. The analysis shows that 83.3% (n=5) of the articles focused on rehabilitative interventions such as muscle strengthening exercises, gait correction, balance exercises, range of motion (ROM), and functional activities, which have been shown to improve motor function and accelerate neurological adaptation. Meanwhile, 16.6% (n=1) of the articles emphasized the importance of close monitoring during the acute phase, focusing on neurological observation, complication prevention, maintaining respiratory stability, and monitoring the risk of increased intracranial pressure. These findings confirm that nursing interventions, which include comprehensive observation, family education, structured therapeutic measures, and multidisciplinary collaboration, significantly optimize neuroplasticity, improve postural control, and maximize muscle strength recovery. Overall, these evidence-based nursing interventions are crucial elements in enhancing the quality of life and independence of children with encephalitis.