Ronny Suwento, Ronny
Departemen Ilmu Penyakit Telinga, Hidung, Dan Tenggorok, Fakultas Kedokteran Universitas Indonesia – RS Cipto Mangunkusumo, Jakarta

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Journal : Paediatrica Indonesiana

Brainstem evoked response auditory in healthy term neonates with hyperbilirubinemia Isman Jafar; Irawan Mangunatmadja; Rinawati Rohsiswatmo; Sudjatmiko Sudjatmiko; Ronny Suwento; Safarina G. Malik
Paediatrica Indonesiana Vol 50 No 3 (2010): May 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.3.2010.144-8

Abstract

Background Bilirubin in healthy term neonates, especially free bilirubin (Bf), could enter brain cell and cause damage perceived by brainstem evoked response auditory (BERA). Studies identify that Bf is more associated to abnonnal BERA than total bilirubin is. Currently, phototherapy is perfonned in neonates with total bilirubin > 15 mg/dL. However, in developing countries where observation could not be done optimally, neonates \\lith totalbilirubin> 12 mg/dL will be subject for phototherapy.Objectives To determine the association between total bilirubin > 12 mg/dL and BERA abnonnalities in healthy tenn neonates, and the value of total bilirubin and free bilirubin that initiate abnonnal BERA.Methods This cross sectional study was carried out between March 31􀁅August 8, 2008, in healthy term neonates at rooming􀁅in ward, Department of Obstetric & Gy necology, Cipto Mangunkusumo Hospital (CMH). All eligible subjects were examined for Bf and BERA using standard methods. Results The prevalence of abnormal BERA was 15.4%. There was no significant relation between hy perbilirubinemia (> 12 mg/ dL) and abnonnal BERA in healthy tenn neonates. Lowest total bilirubin and Bf level related to abnonnal BERA were 12.4 mg/dL (mean 12.8 mg/dL) and O.oS)Lg/dL (mean l.3)Lg/dL), respectively. All BERA abnonnalities were unilateral.Conclusions There is no association between abnormal BERA and hyperbilirubinemia (total bilirubin> 12 mg/dL) in jaundiced infants who undergo phototherapy.
The role of hearing capability test as a screening test for the possibility of hearing disorder in children with speech delay Fatmawaty Fatmawaty; Hartono Gunardi; Ronny Suwento; Abdul Latief; Rulina Suradi; Irawan Mangunatmadja
Paediatrica Indonesiana Vol 46 No 6 (2006): November 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.364 KB) | DOI: 10.14238/pi46.6.2006.255-9

Abstract

Background Hearing disorder may cause speech delay so thatevery child with speech delay should undergo hearing test. Thegold standard for audiometric test is otoacustic emission (OAE)and brainstem evoked response audiometry (BERA). They havehigh sensitivity and specificity, but the availability is limited andexpensive. Hence, both tests are not available at the primary healthcare centers. In 1997, the Department of Health, Republic of Indo-nesia, established a simple subjective test instrument, i.e. the hear-ing capability test (HCT).Objective To asses the accuracy of HCT compared to the goldstandard hearing tests (OAE and/or BERA).Methods This study was a cross sectional study on 89 childrenaged less than 5 years who had speech delay and came to theGrowth and Development Outpatient Clinic or the General Outpa-tient Clinic, Pediatric Neurology Clinic of the Department of ChildHealth, Cipto Mangunkusumo (CM) Hospital; and Center for EarCare and Communicative Disorders (CECCD), Department of ENT,CM Hospital, during March to August 2005.Results HCT sensitivity and specificity were 92.9% and 27.7%,respectively. Positive predictive value (PPV), negative predictivevalue (NPV), positive likelihood ratio (PLR), and negative likehoodratio (NLR) were 84%, 50%, 1.9, and 0.7, respectively.Conclusion The sensitivity and specificity of HCT as a screeningtest of hearing disorder in children with speech delay were 93%and 28%, respectively. Based on this result, HCT should only beused as screening test and not as a diagnostic test