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Analisis Kadar Timbal (Pb) Darah dan Malondialdehid (MDA) Pada Manusia Silver di Kota Semarang Umi Rosidah; Ichsan Hadipranoto
Jaringan Laboratorium Medis Vol 5, No 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9519

Abstract

The danger of lead in paint that is coated on the human body, silver can enter through the skin and will interact with proteins, DNA, RNA and oxidative stress. Formation of Reactive Oxygen Species (ROS) by lead can cause oxidative stress and is characterized by an increase in the enzymes catalase, malondialdehyde (MDA) and Oxidized glutathione (GSSG). The aim of this study was to analyze blood lead levels against Malondealdehyde (MDA) in silver humans in Semarang City. This study used an observational analytic study with a cross sectional approach to analyze the effect of lead levels on Malondialdehyde levels in silver humans in Semarang City using a t test to see differences in results based on length of work, length of exposure and age on lead levels, and the effect of lead on MDA. The results showed that from 20 human samples, the lowest lead level was 23.9 g/dl and the highest was 61.9 g/dl with an average blood lead level of 37.3 g/dl with an average blood lead level of 37.3 g/dl, and the lowest MDA level was 0.4 mg/L and the highest level is 1.74 mg/L with an average of 1.2 mg/L. Based on the data obtained from the t test, it shows a significant value (P-Value) of 0.610 which means 0.05, this indicates that the decision taken is to reject H1 which means that there is no effect between the results of lead levels on the results of MDA levels.
SKRINING HEPATITIS B PADA MAHASISWA YANG MEMENUHI SYARAT SEBAGAI CALON PENDONOR DARAH SUKARELA Adita Puspitasari Swastya Putri; Dina Afrianti; Umi Rosidah
Jurnal Kesehatan Vol. 14 No. 2 (2023)
Publisher : Sekolah Tinggi Ilmu Kesehatan (STIKes) Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38165/jk.v14i2.382

Abstract

Hepatitis B merupakan penyakit menular yang menjadi masalah kesehatan yang besar di masyarakat. Hepatitis B dapat ditularkan melalui penggunaan jarum suntik dan melalui transfusi darah. Perlu dilakukan skrining hepatitis B pada calon pendonor darah sukarela. Tujuan Penelitian ini adalah untuk mengetahui gambaran hepatitis B pada mahasiswa yang memenuhi syarat sebagai calon pendonor darah sukarela. Rancangan penelitian observasional dengan studi cross sectional. Sampel sebanyak 50 mahasiswa dengan teknik stratified random sampling. Penelitian dilakukan di Laboratorium Jurusan Analis Kesehatan Poltekkes Kemenkes Semarang pada bulan juni 2023. Dilakukan penimbangan berat badan, pengukuran tekanan darah, dan pemeriksaan hemoglobin. Memenuhi syarat donor darah apabila seluruh hasil pemeriksaan normal dan sesuai kriteria persyaratan. Data diolah dan di analisis secara deskriptif untuk melihat distribusi frekuensi. Sebagian besar mahasiswa telah memenuhi syarat sebagai calon pendonor darah sukarela yaitu sebanyak 42 (84%) mahasiswa. Seluruh mahasiswa memiliki hasil non reaktif hepatitis B yaitu sebanyak 42 (100,0%) mahasiswa. Sebagian besar mahasiswa memiliki riwayat vaksin hepatitis B yaitu sebanyak 27 (64,3%) mahasiswa. Hasil skrining merupakan pemeriksaan awal, sehingga masih diperlukan pemeriksaan tambahan untuk dapat memberikan kepastian terhadap status penyakit Hepatitis B. Vaksin dianjurkan untuk diberikan kepada seluruh mahasiswa kesehatan yang berisiko tinggi terhadap penularan virus hepatitis B.Kata Kunci: Skrining; Hepatitis B; Seleksi Donor; Donor Darah SukarelaAbstractHepatitis B is a contagious disease posing a significant health issue in the community. Hepatitis B can be transmitted through the use of syringes and through blood transfusions. Screening for hepatitis B is necessary for prospective voluntary blood donation. This study aimed to determine the prevalence of hepatitis B among students who fulfilled the criteria as potential voluntary blood donation. This study used an observation with a cross-sectional approach. Around 50 students were selected as the respondents using a stratified random sampling technique. The study was conducted at the Laboratory of the Department of Health Analysts at Semarang Polytechnic of Health in June 2023. Weight measurement, blood pressure measurement, and hemoglobin examination were performed on the respondents and they were eligible blood donation if all examination results were normal and met the criteria. Data were processed and analyzed descriptively to see the frequency distribution. Most of the students met the requirements as potential voluntary blood donation specifically 42 students (84%). All students had non-reactive hepatitis B results, totaling 42 students (100.0%). Most students had a history of hepatitis B vaccination, with 27 students (64.3%) having received the vaccine. The screening result represents an initial examination, therefore additional tests are still needed to provide certainty about the status of Hepatitis B. Vaccination is recommended to be administered to all students majoring in medicine who are at high risk of hepatitis B virus transmission.Keywords: Screening; Hepatitis B; Donor Selection; Voluntary Blood Donation
PELATIHAN PENGGUNAAN ALAT POCT BAGI KADER KESEHATAN DAN IBU-IBU PKK SEBAGAI UPAYA PENCEGAHAN PENYAKIT TIDAK MENULAR (PTM) PADA MASYARAKAT Ririh Jatmi Wikandari; Qurrotu A’yuni Auliya; Umi Rosidah; Hilari Rio Rosa Nastiti
MIMBAR INTEGRITAS : Jurnal Pengabdian Vol 5 No 1 (2026): JANUARI 2026
Publisher : Biro Administrasi dan Akademik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/mimbarintegritas.v5i1.6845

Abstract

Penyakit Tidak Menular (PTM) adalah isu kesehatan masyarakat yang angkanya terus bertambah. Salah satu hambatan dalam pencegahan adalah kurangnya pengetahuan dan keterampilan masyarakat, terutama kader kesehatan dan ibu-ibu PKK, dalam melakukan deteksi dini secara mandiri. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memperkuat kemampuan kader dan para ibu PKK dalam memanfaatkan alat Point of Care Testing (POCT) sebagai langkah awal dalam skrining PTM. Pendekatan yang diterapkan adalah partisipatif-edukatif melalui pelatihan terencana yang meliputi penyuluhan, diskusi, dan praktik langsung dalam penggunaan alat POCT seperti glukometer dan tensimeter digital. Tahapan kegiatan meliputi kolaborasi dengan mitra, penyusunan materi dan alat, pelaksanaan pelatihan, serta evaluasi dengan pre-test dan post-test. Acara ini dilakukan pada 17 Mei 2025 dengan peserta yang terlibat dari kelompok kader dan PKK. Evaluasi menunjukkan bahwa 91% peserta mengalami peningkatan pengetahuan dan keterampilan dalam penggunaan alat POCT dengan benar. Di samping itu, pemeriksaan kesehatan dasar juga dilaksanakan, dengan hasil 52% peserta memiliki IMT obesitas, 48% tekanan darah dalam batas normal, dan 24% kadar glukosa darah melebihi normal. Penemuan ini menggarisbawahi signifikansi keterlibatan masyarakat dalam skrining mandiri guna mengurangi risiko komplikasi PTM. Pelatihan ini terbukti sukses dalam mendukung inisiatif promotif dan preventif pada tingkat komunitas sesuai dengan kebijakan layanan kesehatan primer nasional.
Deteksi Karsinoma Nasofaring Mengunakan Rapid Test Uji Imunokromatografi pada Petugas SPBU Roni Afriansya; Umi Rosidah; Eko Naning Sofyanita
Jaringan Laboratorium Medis Vol 5 No 1 (2023): Mei 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9337

Abstract

Nasopharyngeal cancer (NPC) is the 4th most common malignancy in Indonesia, after breast, cervical and lung cancer. The risk factors for this cancer are Epstein-Barr virus, gender, race, adult age 30-50 years, family history, drinking alcohol and smoking. The prevalence of NPC in Indonesia is 6.2/100,000, with nearly 13,000 new cases, but this is a small proportion that has been documented. Adham et al (2012) reported that NPC is the most common head and neck cancer (28.4%), with a male-female ratio of 2:4 and is endemic to the island of Java. The existence of knowledge about NPC starting from prevention, early detection, appropriate treatment will be able to help overcome problems caused by nasopharyngeal cancer. Early detection is very important. If NPC is found at an early stage, the cure rate is quite high, reaching 90%. The purpose of this study was to find out whether there were gas station workers in Semarang City who experienced NPC. This study used an analytic survey method with a cross-sectional approach. The results of the study of 20 Semarang City Gas Station officers found that the characteristics based on age were the most in the range 31-50, namely 70%. Characteristics based on gender of the 20 gas station attendants are all male (100%). Characteristics based on length of service are 1 - 10 years (35%), 11 - 20 years (35%) and 21 - 30 years (30%) respectively. Characteristics based on smoking history, 55% of respondents smoked and 45% did not smoke. And the NPC examination results of all respondents (100%) were NPC negative.
Analisis Kadar Timbal (Pb) Darah dan Malondialdehid (MDA) Pada Manusia Silver di Kota Semarang Umi Rosidah; Ichsan Hadipranoto
Jaringan Laboratorium Medis Vol 5 No 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9519

Abstract

The danger of lead in paint that is coated on the human body, silver can enter through the skin and will interact with proteins, DNA, RNA and oxidative stress. Formation of Reactive Oxygen Species (ROS) by lead can cause oxidative stress and is characterized by an increase in the enzymes catalase, malondialdehyde (MDA) and Oxidized glutathione (GSSG). The aim of this study was to analyze blood lead levels against Malondealdehyde (MDA) in silver humans in Semarang City. This study used an observational analytic study with a cross sectional approach to analyze the effect of lead levels on Malondialdehyde levels in silver humans in Semarang City using a t test to see differences in results based on length of work, length of exposure and age on lead levels, and the effect of lead on MDA. The results showed that from 20 human samples, the lowest lead level was 23.9 g/dl and the highest was 61.9 g/dl with an average blood lead level of 37.3 g/dl with an average blood lead level of 37.3 g/dl, and the lowest MDA level was 0.4 mg/L and the highest level is 1.74 mg/L with an average of 1.2 mg/L. Based on the data obtained from the t test, it shows a significant value (P-Value) of 0.610 which means > 0.05, this indicates that the decision taken is to reject H1 which means that there is no effect between the results of lead levels on the results of MDA levels.
Faktor Risiko Terjadinya Anemia pada Pasien Tuberculosis Paru dalam Fase Pengobatan Umi Rosidah; Qurrotu Ayuni Auliya; Ririh Jatmi Wikandari; Santo Yoseph Didik Widiyanto
Jaringan Laboratorium Medis Vol 6 No 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12268

Abstract

Tuberculosis lungs is disease infectious disease caused by bacteria Mycobacterium tuberculosis. Tuberculosis is still a disease become threat health Indonesian society which  leads to illness , disability and death tall so that need existence mitigation. Research objectives know factor risk the occurrence of anemia in patients tuberculosis lungs in phase treatment . Study This is study retrospective analytic case control Study carried out at the Community Health Center Very Beautiful Subdistrict Genuk City of Semarang. Population all TB patients who are undergo treatment at the Community Health Center Bangetayu. Research sample This from the total population namely 34 case and control patients. The results of 34 respondents case control there is level hemoglobin in patients Tuberculosis lungs with anemia (case) as many as 17 respondents experienced decline hemoglobin levels, namely man with an average hemoglobin level of 12.2 gr/dL (7 respondents), women with The average hemoglobin level was 10.6 gr/dL (2 respondents). A total of 17 respondents non - anemic control , namely the majority is normal with type sex Woman with an average Hemoglobin level of 12.61 gr/dL (17 respondents ). Based on characteristics what kind sex male 29.41% and gender sex women 11.76%. Decrease hemoglobin levels , namely man with an average hemoglobin level of 12.2 gr/dL (5 respondents), women with average hemoglobin level 10.6 gr/dL (2 respondents). Based on characteristics of the type sex women 70.59% (24 respondents) and men 29.41% (10 respondents). Based on characteristics age category adults 64.71% (22 respondents), elderly 23.53% (8 respondents), infants and children 11.76% (4 respondents), and adolescents 0.00% (0 respondents). The results of the bivariate test of hemoglobin levels, age , and type sex there is connection between hemoglobin levels, age, and type sex to Pulmonary Tuberculosis patients in phase treatment. The most influential risk factor o to the occurrence of anemia in patients with pulmonary tuberculosis in phase treatment namely on the variables type sex that is own risk of 3,429. Next followed by variables hemoglobin levels that have risk of 0.370. Age No there is factor risk the occurrence anemia in pulmonary tuberculosis patients in phase treatment. The conclusion of this study is that hemoglobin levels and sex are risk factors for anemia in patients with pulmonary tuberculosis in the treatment phase. Anemia can affect the diagnosis, prognosis, complications, and response to tuberculosis therapy, so that tuberculosis patients can maintain nutritional intake and therapy compliance to suppress the progression of the disease.