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All Journal PCJN Pharmaceutical and Clinical Journal of Nusantara
Cucu Arum Dwi Cahaya
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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TESTING THE EFFECTIVENESS OF BIDARA LEAF ETHANOL EXTRACT (Ziziphus mauritiana L.) IN GEL PREPARATIONS FOR BURN WOUNDS IN MALE RABBIT (Oryctolapus cuniculus) Sulasmi Sulasmi; Angga Nugraha Sanjaya; Sofia Elia Sari Bangun; Cucu Arum Dwi Cahaya
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 01 (2022): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.99 KB) | DOI: 10.58549/pcjn.v1i01.2

Abstract

Abstract Bidara plants have many benefits in the treatment of sore skin, ulcers, and burns. Burns are a form of tissue damage or loss caused by contact with a heat source such as fire, hot water, electricity, radiation, or corrosive substances. This study aims to determine the effectiveness of the ethanol extract of bidara leaf in healing burns in male rabbits compared to bioplacenta. This study used an experimental method of maceration extraction using 96% ethanol. To test the effect of burns, 15 test animals were grouped into five groups, each of which used three test animals. The treatment group was a gel-based negative control group, a positive bioplacenta control group, and a treatment group with bidara leaf ethanol extract at concentrations of 5%, 10%, and 15%. The results of the research on the effectiveness of healing burns in the three formulations, namely a concentration of 15%, showed faster healing of wound diameter in male rabbits compared to concentrations of 5% and 10% but were not more effective when compared to bioplacenta ointment. Keywords: Bidara leaf ethanol extract, burns, ointment and bioplacenton
Co-Authors Angga Nugraha Sanjaya Sofia Eliasari Br Bangun Sulasmi Sulasmi