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All Journal Jurnal Indonesia Sosial Sains Jurnal Pengabdian Ilmu Kesehatan
Fitriana Fitriana
Universitas Megarezky
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Skrining Kesehatan Melalui Pemeriksaan Asam Urat di Kompleks Aditarina Kota Makassar Mutmainnah Abbas; Rosdiana Mus; Thaslifa Thaslifa; Yanti Sunaidi; Fitriana Fitriana
Jurnal Pengabdian Ilmu Kesehatan Vol. 3 No. 1 (2023): Maret : Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v3i1.1670

Abstract

Degenerative disease is one of the classes of diseases whose incidence is related to the degeneration process in old age whose development is directly related to time and age. This usually affects the joints, namely gout. Uric acid is the final metabolic product of purine, which is a component of nucleic acid found in the nucleus of body cells. Increased uric acid levels in the blood are not only caused by food consumed but there are several other factors, namely age, gender, body mass index, and genetics. In addition, in the elderly there is a decrease in the function of vital organs such as the liver and kidneys which can cause an increase in uric acid levels in the blood. The purpose of this study is health screening through uric acid examination. The method used was descriptive by involving 27 respondents who were willing to become subjects. The results showed that there were 10 respondents with increased uric acid examination results while 17 subjects showed normal uric acid examination results.
The Relationship Between Duration of Hypertension and Serum Creatinine, Urea, and Estimated Glomerular Filtration Rate (EGFR) in Hypertensive Patients Fitriana Fitriana; Hastuti Herman
Jurnal Indonesia Sosial Sains Vol. 7 No. 6 (2026): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v7i6.2394

Abstract

Hypertension, defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg, affects 34.1% of Indonesia's population according to the Indonesian Basic Health Research. Uncontrolled and long-standing high blood pressure can damage the glomerular structure, leading to decreased kidney function characterized by increased urea and creatinine levels, as well as a reduced glomerular filtration rate (eGFR), which is the main indicator for staging chronic kidney disease. The purpose of the study is to analyze the relationship between the duration of hypertension and kidney function biomarkers, namely creatinine, urea, and estimated glomerular filtration rate (eGFR), in hypertensive patients. This research method uses an observational analytical design with a purposive sampling technique, involving a total of 30 patients with grade 1 and grade 2 hypertension. The results of the examination of kidney function biomarkers (creatinine, urea, and eGFR) in relation to the duration of hypertension, based on the nonparametric Kendall's tau correlation test, showed no significant relationship between creatinine values and duration of hypertension (p = 0.061, p > 0.05), nor between urea values and duration of hypertension (p = 0.198, p > 0.05); however, a significant relationship was found between eGFR and duration of hypertension (p = 0.006, p < 0.05). Thus, it can be concluded that eGFR is a potential biomarker in laboratory examinations for assessing the risk of kidney damage complications in hypertensive patients. It is recommended that people with hypertension undergo regular kidney function checks in order to reduce the risk of long-term complications.
Co-Authors Hastuti Herman Mus, Rosdiana Mutmainnah Abbas Thaslifa Thaslifa Yanti Sunaidi