Garuda - Garba Rujukan Digital

CORRELATION BETWEEN COMPUTER VISION SYNDROME AND UPPER LIMB DISORDERS AT WIDYA MANDALA CATHOLIC UNIVERSITY SURABAYA Michael Christian Iskandar; Pauline Meryana; Paulus Alexander Supit
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 5, No 2 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v5i2.4652

Background: The world of technology that continues to develop, especially in computer, makes workers spend more time operating electronic devices. This can contribute to eye strain which is one of the most common symptoms of Computer Vision Syndrome (CVS). CVS may associated with musculoskeletal disorders, especially at upper extremities due to non-ergonomic body position, which can be referred to as Upper Limb Disorders (ULD). Therefore, CVS can affect the severity of ULD.Purpose: To explain correlation between CVS with ULD to students at Widya Mandala Catholic University Surabaya.Methods: Analytics observational was the type of this research and the research design was cross sectional study.Result: The groups of respondents who experienced CVS with the severity of ULD on a scale 0 (A): no pain; scale 1 (B): moderately painful; scale 2 (C): painful; scale 3 (D): very painful were found to be 34.3%, 25%, 2.3% and 0%. And the groups of respondents who did not experience CVS with the severity of ULD on a scale 0 (A), scale 1 (B), scale 2 (C), and scale 3 (D) were found to be 35.5%, 2.9%, 0%, and 0%. Results from Spearman test found that the p=0.000 so there’s a significant correlation between the two variables with a weak correlation coefficient (r=0,39).Conclussion: There was correlation between CVS and ULD with a weak correlation coefficient value in students at Widya Mandala Catholic University Surabaya

THE RELATIONSHIP BETWEEN STRESS AND THE SLEEP QUALITY OF HEALTH WORKERS DURING THE COVID 19 PANDEMIC Priskila Sekar Dharana Tantadiputra; Paulus Alexander Supit; Tabita Novita Anggriani
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 5, No 2 (2023): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v5i2.3717

Psychological stress is the body’s way to cope with stressors. We are not able to evade stressors. In fact, we need stressors to keep ourselves going. So stress to an extent is a good thing. It is harmful when it becomes a distress, in which it starts to affect our bodily function, including our sleep quality. Psychological stress will activate the body’s HPA-axis and the sympathetic pathway of the autonomic nervous system, releasing hormones such as Cortisol and Catecholamine. These hormones can cause the disturbance of sleep. The aim of this study is to find the relation between the level of stress and the sleep quality in healthcare workers during the COVID-19 pandemic. PSS (Perceived Stress Scale) was used to calculate the level of stress and PSQI (Pittsburgh Sleep Quality Index) was used to calculate sleep quality. In this study we found that the level of stress is related to sleep quality in healthcare workers during the COVID-19 pandemic. The relation is positive, significant (P = 0.002), and moderate (r = 0.4). To conclude, there is a relation between stress and sleep in healthcare workers during the COVID-19 pandemic.

CLINICAL PROFILE OF STROKE PATIENTS IN GOTONG ROYONG HOSPITAL Supit, Paulus; Kurniawati, Nita; Kartikasari, Desy; Raymond Desun, Evander Aloysius; Erwin, Ferdinand
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 6, No 3 (2024): July
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v6i3.5781

Background: Stroke is a global health issue due to its high prevalence, mortality, and associated disabilities. The Global Burden of Disease Study identifies ischemic and hemorrhagic strokes as significant contributors to global health burdens. Understanding these factors in different populations is crucial for developing targeted interventions and improving patient outcomes.Methods: This retrospective descriptive study analyzed medical records of stroke patients at Gotong Royong Hospital from January to December 2023. Patients aged 18 years or older with acute stroke confirmed by CT or MRI were included.Results: Out of 224 stroke patients, 58% were male and 42% female. Most patients were over 70 years old (31.7%), with 29% aged 51-60 and 26.3% aged 61-70. Ischemic stroke was predominant (91.5%), while 8.5% had hemorrhagic stroke. Many patients (40.2%) arrived at the emergency department more than 24 hours after symptom onset. Hypertension was present in 68.8% of patients, diabetes in 36.6%, and dyslipidemia in 24.1%. The average length of stay was 4.13 days. Blood pressure measurements showed high prevalence of Grade 2 hypertension in systolic (37.05%) and prehypertension in diastolic (30.80%). Laboratory results revealed mean random blood glucose of 174.3 mg/dL, fasting blood glucose of 110.42 mg/dL, HbA1C of 8.06%, LDL cholesterol of 120.31 mg/dL, and triglycerides of 151.26 mg/dL.Conclusion: The majority of acute stroke patients at Gotong Royong Hospital are male, over 60, with ischemic stroke, and present more than 24 hours post-onset. These patients typically have a history of hypertension but no previous strokes, with an average hospital stay of 4 days. Many exhibit Grade 2 hypertension in systolic blood pressure and prehypertension in diastolic pressure. Understanding these profiles can guide better management and preventive strategies for stroke patients.

PENYULUHAN KESEHATAN PENCEGAHAN DAN PENANGANAN NYERI PUNGGUNG BAWAH Kartikasari, Desy; Supit, Paulus Alexander; Kurniawati, Nita; Erwin, Ferdinand
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.22061

Nyeri punggung bawah (NPB), seperti yang didefinisikan oleh Persatuan Dokter Saraf Indonesia (PERDOSSI), merupakan persepsi nyeri yang terlokalisasi pada daerah punggung bagian bawah, dapat berupa nyeri lokal atau radikuler, atau keduanya. Nyeri ini terjadi di antara sudut iga terbawah dan lipat bokong bawah, yang merupakan daerah lumbal atau lumbosakral, seringkali disertai dengan penjalaran nyeri ke arah tungkai dan kaki. Berdasarkan penelitian multisenter PERDOSSI, sebanyak 18,37% dari 819 orang yang menjadi subjek penelitian pada 14 rumah sakit pendidikan Indonesia pada Mei 2002 mengalami NPB. Kejadian NPB ini terkait dengan berbagai faktor risiko, termasuk karakteristik pekerjaan, faktor lingkungan, aktivitas fisik, serta faktor genetik. NPB menjadi masalah kesehatan global yang umum, menyebabkan pembatasan aktivitas dan disabilitas kerja. Pentingnya penanganan NPB tercermin dalam data disabilitas terkait NPB di negara Barat, di mana sekitar 45-55% populasi pekerja mengalami NPB dalam periode 12 bulan. Penanganan NPB melibatkan pendekatan farmakologis dan non-farmakologis. Kegiatan ini merupakan kegiatan penyuluhan kesehatan yang bertujuan untuk meningkatkan pengetahuan masyarakat umum mengenai nyeri punggung bawah.

THE EFFECT OF ROSEMARY ESSENTIAL OIL (ROSMARINUS OFFICINALIS L.) ON IMPROVING SHORT-TERM MEMORY IN ELDERLY PEOPLE Bulain, Jessica Julia; Suyono, Handi; Supit, Paulus Alexander
JURNAL WIDYA MEDIKA Vol. 11 No. 1 (2025): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v11i1.7504

Memory is the human ability to receive and store information. With increasing age, the brain's work function will also experience a decline, which will have an impact on individual cognitive function. Memory decline is a common thing that occurs in people of older age. Rosemary essential oil is one of the additional therapies that are useful in improving working memory and short-term memory. This study aims to determine the effect of rosemary essential oil on short-term memory in elderly people. This research is quasi-experimental with group control, with data collection techniques, namely, random sampling. The research was measured using the digit span test as a short-term memory test involving 32 elderly respondents with an age range of 65-85 years. This research was conducted by administering rosemary essential oil to the treatment group and jojoba oil to the control group by inhalation using a mask for 7 days in the morning, with the results of the pretest and posttest comparison between the two groups then analyzed using the Wilcoxon test. The results obtained from the study were that there was a significant value in the experiment group given rosemary essential oil, namely with a p-value of (p<0.005), which means that there is an influence between rosemary essential oil and short-term memory.

The Role of Probiotics in Improving Motor Function in Parkinson’s Disease: Evidence from a Systematic Review and Meta-Analysis Andra Danika; Paulus Alexander Supit
The International Journal of Medical Science and Health Research Vol. 16 No. 3 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/qbay7381

Introduction: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor deterioration that profoundly impacts functional independence and quality of life. Recent advances suggest that the gut–brain axis contributes to PD pathophysiology, with gut dysbiosis potentially exacerbating neuroinflammation and α-synuclein pathology. Probiotics have emerged as a novel therapeutic approach, but their effect on motor outcomes remains uncertain. Objective: To evaluate the efficacy of probiotic supplementation in alleviating motor deterioration in PD, with Unified Parkinson’s Disease Rating Scale Part III (UPDRS III) scores as the primary outcome. Methods: A systematic review and meta-analysis were conducted in accordance with PRISMA 2020 guidelines. PubMed, Cochrane Library, and ScienceDirect were searched from inception to February 2025. Eligible studies were randomized controlled trials comparing probiotics with placebo or usual care in adults with PD. The primary outcome was mean change in UPDRS III scores. Risk of bias was assessed using the Cochrane RoB 2.0 tool, and certainty of evidence was graded with GRADE methodology. Random-effects models were applied to calculate pooled mean differences (MD) with 95% confidence intervals (CI). Results: From 294 records, five RCTs comprising 317 participants met the inclusion criteria. Pooled analysis demonstrated a significant improvement in motor function with probiotics compared to control (MD –3.15, 95% CI –5.76 to –0.54; p = 0.02). The direction of effect consistently favored probiotics across all trials, although heterogeneity was moderate (I² = 65%). Adverse events were infrequent and mild, primarily consisting of transient gastrointestinal discomfort. No serious probiotic-related adverse events were reported. Discussion: This analysis highlights the potential role of probiotics as a safe and accessible adjunctive strategy in PD management. The magnitude of improvement in UPDRS III exceeds the minimal clinically important difference, suggesting clinically meaningful benefits. Nevertheless, variability in probiotic formulations, small sample sizes, and short treatment durations limit generalizability. Integration of microbiome profiling and biomarker assessment in future trials may clarify mechanisms of action and identify patient subgroups most likely to benefit. Conclusion: Probiotic supplementation appears to provide a modest but clinically relevant improvement in motor function in PD, as measured by UPDRS III. While promising, further large, standardized, and long-term RCTs are required before probiotics can be integrated into routine PD care.

ANALYSIS OF STROKE RISK FACTORS ON THE FREQUENCY OF RECURRENT STROKE EVENTS IN ACUTE ISCHEMIC STROKE PATIENTS Kurniawati, Nita; Supit, Paulus Alexander; Erwin, Ferdinand
JURNAL WIDYA MEDIKA Vol. 10 No. 2 (2024): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v10i2.6033

Introduction: Ischemic strokes making up over three quarters of all cases are a major global cause of disability and mortality. Survivors face a 15% risk of recurrence within two years, with recurrent strokes often resulting in more severe neurological damage and increasing the risk of death and long-term disability. Methods: This retrospective cross-sectional study analyzed medical records from Gotong Royong Hospital in Surabaya from January 2023 to June 2024, selecting patients with acute ischemic stroke and a history of prior strokes. The data were descriptively analyzed and further examined using bivariate analysis to identify correlations with recurrent stroke episodes, followed by a multivariate regression analysis. Results: The study recruited 87 participants, predominantly male (64.4%), with an average age of 63.2 years and varying medical histories, including hypertension (79.3%), diabetes mellitus (46%), and dyslipidemia (31%). Bivariate analysis revealed no significant correlations between hyperten

Vitamin D Supplementation and its Effect on Modified Rankin Scale and National Institutes of Health Stroke Scale Outcomes in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis Andra Danika; Paulus Alexander Supit; Maria Stefanny Setiawan
The International Journal of Medical Science and Health Research Vol. 18 No. 7 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/99rg7932

Introduction: The role of vitamin D in functional recovery after acute ischemic stroke remains unclear due to inconsistent evidence. This systematic review and meta-analysis aim to evaluate the effect of vitamin D supplementation on functional and neurological recovery, as measured by the modified Rankin Scale (mRS) and the National Institutes of Health Stroke Scale (NIHSS), in adult patients with acute ischemic stroke. Methods: Following PRISMA 2020 guidelines, a systematic search was conducted in PubMed, Google Scholar, and Semantic Scholar for randomized controlled trials and meta-analyses since 2015. Eligible studies included adult ischemic stroke patients receiving vitamin D supplementation with reported mRS or NIHSS outcomes. Data were synthesized, and random-effects meta-analyses calculated pooled hazard ratios (HRs). Results: Vitamin D supplementation was associated with significant improvements in mRS (HR 1.32) and NIHSS (HR 1.30). However, substantial heterogeneity was observed (mRS I² = 78.4%; NIHSS I² = 77%). Variability largely stemmed from differences in supplementation regimens (single high-dose injection vs. daily oral) and the baseline vitamin D status of participants. Discussion: Findings suggest vitamin D may enhance post-stroke recovery, though the benefit is not consistent across populations. Improvements were most evident among patients with pre-existing deficiency, indicating supplementation may be particularly effective as corrective therapy. Variation in dosage and timing complicates the formulation of a single treatment recommendation Conclusion: Vitamin D supplementation is associated with a statistically significant improvement in functional and neurological outcomes for patients with acute ischemic stroke, as measured by the mRS and the NIHSS. The pooled data suggests a beneficial role for vitamin D in post-stroke recovery

Peran Probiotik Terhadap Perbaikan Gejala Motorik Pada Pasien Dengan Penyakit Parkinson: Sebuah Meta-Analisis Erwin, Ferdinand; Meryana, Meryana; Kurniawati, Nita; Kartikasari, Desy; Supit, Paulus A
Journal of Medicine and Health Vol 6 No 2 (2024)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/jmh.v6i2.8805

Penyakit Parkinson merupakan penyakit neurodegeneratif paling sering diderita kedua setelah penyakit Alzheimer, yang ditandai dengan adanya bradikinesia, tremor saat istirahat, dan rigiditas. Penanda utama dari penyakit Parkinson adalah patologi α-synuclein yang disebut dengan Lewy Body. Beberapa penelitian terbaru menunjukkan peran gut dysbiosis menjadi salah satu faktor dalam patofisiologi penyakit Parkinson. Beberapa penelitan sebelumnya menunjukkan efektivitas probiotik terhadap perbaikan klinis penyakit Parkinson. Tujuan dari penelitian ini adalah untuk menganalisis peran probiotik terhadap gejala motorik pasien dengan penyakit Parkinson. Metode penelitian ini adalah dengan melakukan pencarian studi melalui berbagai database seperti Pubmed, Scopus, Cochrane, dan ProQuest. Studi yang didapatkan kemudian dilakukan skrining, penilaian kualitas studi, dan analisis kuantitatif. Hasil penelitian ini didapatkan total 5 studi yang melibatkan 339 pasien dengan penyakit Parkinson. Meta-analisis penelitian ini menunjukkan penurunan skor Unified Parkinson’s Disease Rating Scale Part III (UPDRS-III) secara signifikan (standardized mean difference: -0,25; interval kepercayaan 95%, -0,44 hingga -0,06) pada pasien dengan penyakit Parkinson setelah pemberian probiotik. Penelitian ini menunjukkan bahwa probiotik dapat memperbaiki gejala motorik secara signifikan pada pasien dengan penyakit Parkinson yang diukur dengan skala UPDRS-III, serta relatif aman dan dapat ditoleransi dengan baik.

Mirogabalin 15 mg Twice Daily for Reduction of Average Daily Pain Score in Neuropathic Pain: Systematic Review and Meta-analysis of Randomized Controlled Trials Andra Danika; Paulus Alexander Supit
The International Journal of Medical Science and Health Research Vol. 22 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/zz360g32

Background: Neuropathic pain is a chronic condition that significantly impairs quality of life, causing sleep disturbance, depression, and functional disability. Standard first-line treatments such as pregabalin and gabapentin are frequently limited by insufficient efficacy or poor tolerability. Mirogabalin is a novel α2δ ligand with slower dissociation from the α2δ-1 subunit of voltage-gated calcium channels, potentially offering sustained analgesia with improved tolerability. Objective: To systematically review and meta-analyze randomized controlled trials (RCTs) assessing the efficacy and safety of mirogabalin 15 mg twice daily compared with placebo in adult patients with neuropathic pain. Methods: This systematic review and meta-analysis followed PRISMA 2020 guidelines. PubMed, Embase, and Cochrane CENTRAL were searched from database through September 2025 for double-blind, placebo-controlled RCTs. The primary outcome was mean change from baseline in average daily pain score (ADPS). Secondary outcomes included ≥30% pain responder rate and treatment-emergent adverse events. Random-effects meta-analysis was performed to calculate pooled mean difference (MD) and risk ratio (RR) with 95% confidence intervals (CIs). Risk of bias was assessed using Cochrane RoB 2.0. Results: Four RCTs with a total of 1,819 participants were included. Mirogabalin significantly reduced ADPS compared with placebo (pooled MD −0.57, 95% CI −0.73 to −0.41; p < 0.00001; I² = 0%). Pooled analysis of dichotomous outcomes demonstrated a significantly greater likelihood of achieving ≥30% pain reduction with mirogabalin (RR 1.26, 95% CI 1.11–1.44; p < 0.01). Most studies had low risk of bias. The most common adverse events were somnolence and dizziness, which were generally mild to moderate. Conclusions: Mirogabalin 15 mg twice daily significantly improves pain outcomes compared with placebo, both in mean ADPS reduction and responder rate, and is generally well tolerated. Although the mean pain reduction is modest, the improved responder rate suggests that a clinically meaningful proportion of patients may benefit. Further research should explore long-term efficacy, optimal dosing, and predictors of response.

Title

Found 11 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 11 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 11 Documents
Search