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Increased knowledge of thalassemia promotes early carrier status examination among medical students Dewanto, Julius Broto; Tansah, Haryono; Dewi, Sari Puspa; Napitu, Helena; Panigoro, Ramdan; Sahiratmadja, Edhyana
Universa Medicina Vol 34, No 3 (2015)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.220-228

Abstract

BACKGROUNDThalassemia is an autosomal recessive genetic disorder, in which the patient requires life-long blood transfusion. As Indonesia harbors 6 to 10% thalassemia carriers, thalassemia prevention measures such as early screening and education in the community are urgently needed. The aim of this study was to explore the knowledge, attitude and practice about thalassemia among young medical students. METHODSA cross-sectional analytic observational study was conducted on 179 subjects in 2015, using a questionnaire with items on knowledge, attitude and practice about thalassemia for data collection. After signing informed consent, the questionnaire was filled in by the students and a blood test was performed when the students agreed to be examined. Detection of probable thalassemia carrier status was done by determination of hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin. RESULTSThe knowledge about thalassemia of the first year medical students (n=179) was good (21.1%), moderate (70.9%) and poor (21.1%). Only 67 (38.3%) of the students agreed to a blood examination for determination of their carrier status after filling-in the questionnaire. The knowledge of thalassemia among first year medical students was statistically related to the timing when they would agree to have their thalassemia carrier status examined (p=0.021, one way ANOVA test). CONCLUSIONA higher thalassemia knowledge score causes medical students to be willing to undergo thalassemia carrier status examination at an earlier point in timing. A well-organized educational program focusing on thalassemia and early screening in young adults may enhance the thalassemia prevention program.
Correlation between Heredity Factor and Menarcheal Age among Adolescent Aged 9–15 Years Old Khotimah, Nurul; Fadil, R.M. Ryadi; Tansah, Haryono
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.626 KB) | DOI: 10.15850/amj.v4n2.1081

Abstract

Background: Menarche is a sign of maturity of the female reproductive function. It is influenced by many factors, such as heredity, general health status, nutrition, and socioeconomic status. The purpose of this study is to determine the correlation of heredity and menarcheal age.Methods:This study was a cross-sectional analytic study conducted from September–October 2014 in Bandung using a multi-stage sampling technique and it was  conducted in twelve elementary schools and junior high schools. A total of 123 subjects were included in this study. The instrument of this study was questionnaire containing menarcheal age of subject, older sister, biological mother, and maternal grandmother. The data were analyzed using Spearman correlation and linear regression test with the level of significance was determined at p<0.05. Results: Among 123 data, the majority of subjects had experienced menarche at the age of 11 (39%) and 12 years (36.6%) with an average of 11.46 years old. Based on the Spearman correlation and multiple linear regression tests, there was a correlation between heredity and menarcheal age. (P=0.00).Conclusions: There is a correlation between heredity and menarcheal age, with the highest correlation is between subject’s and older sister’s menarcheal age.  DOI: 10.15850/amj.v4n2.1081
Motoric Clinical Symptoms in Late Onset Parkinson’s Disease at Dr. Hasan Sadikin General Hospital Bandung Sivakurunathan, Jasvinee; Syamsudin, Thamrin; Tansah, Haryono
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (543.61 KB)

Abstract

Background: Parkinson’s disease (PD) is a progressive neurological that disorder is characterized by a number of motoric symptoms which are resting tremor, bradykinesia, rigidity and postural disturbance. The main aim in carrying out this study was to observe the motoric clinical pattern in patients with late onset Parkinson’s disease based on age, gender, and staging of the disease.Methods: This was a descriptive retrospective study to 89 medical record of patients with late onset Parkinson’s disease from Neurology outpatient clinic of Dr. Hasan Sadikin General Hospital Bandung in the period January 2010 to January 2013. Total sampling was used to determine the population sample size The motoric clinical symptoms in patients with late onset Parkinson’s disease were classified based on age at diagnosis, gender, and staging of the disease conducted using descriptive retrospective method. Besides, staging was made based on Hoehn and Yarl scale.Results: Overall, 92% of the patients with late onset Parkinson’s disease had resting tremor, and postural instability was less frequently found in 21% of patients. Sixty one men suffered from this disease, 43% were from the age group 60–69, and 32% were in stage III.Conclusions: A majority of patients with the late onset Parkinson’s disease show resting tremor that has the common motoric clinical pattern, followed by bradykinesia, rigidity, and some show postural instability. [AMJ.2017;4(1):11–5]DOI: 10.15850/amj.v4n1.1013
Knowledge, Attitude, and Practice Towards Thalassemia Prevention among College Students in Universitas Padjadjaran, Bandung, Indonesia Kusumadewi, Ratu Istihajar; Tansah, Haryono; Widjadjakusumah, Anggraini
Althea Medical Journal Vol 10, No 3 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Thalassemia is the most common hereditary anemia disease. Sixty thousand thalassemia major patients are born each year and require continuous blood transfusion to survive, meanwhile 12% die in the perinatal period due to anaemic conditions. Specifically in Indonesia, 10% of the societies are deemed to be carriers, but the studies on thalassemia prevention are still limited.. This study aimed to explore the correlations between knowledge, attitude, and practice (KAP) of college students toward thalassemia prevention.Methods: This study was a cross-sectional analytic study conducted in September−October 2015. A total of 536 respondents from various faculties in Universitas Padjadjaran were gathered based on purposive sampling. The data obtained from validated questionnaires were analyzed by Spearman’s Rank correlation test.Results: The correlation between knowledge and attitude was weak, but the p-value was significant (rs= +0.388, ρ= 0.041). Yet, there was no correlation between knowledge and practice (rs= +0.280, ρ= 0.063), nor between attitude and practice (rs = +0.012, ρ= 0.786).Conclusions: Knowledge positively affects college students’ attitude to thalassemia prevention; however, it does not have the same effect on its practice. It is consistent with the attitude, which also does not correlate with the practice of college students toward thalassemia prevention. Therefore, other affirmative actions or direct interventions and programs are still needed to maximize  thalassemia prevention.