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All Journal Indonesian Journal of Pharmaceutical Science and Technology Inovasi Kesehatan Global
Anna Choirunnisa, Anna
Fakultas Farmasi Universitas Jenderal Achmad Yani, Jalan Terusan Jend. Sudirman, Cimahi.
Computer Science & IT Medicine & Pharmacology Nursing Public Health

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Water Extract Influence of Stachytarpheta jamaicensis (L.) Vahl Leaves to Prevent Psoriasis Severity in Animal Model Encep Abdurahman; Nengdiana Permana; Grace S. Mardiana; Afifah B. Sutjiatmo; Anna Choirunnisa; Suci N. Vikasari
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 3, No. 1 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.36335

Abstract

Psoriasis is an autoimmune disease that is characterized by the appearance of lesions on the skin. The current treatment aims to control the symptoms. The efficacy of Stachytarpheta jamaicensis (L.) Vahl’s for autoimmune rheumatoid arthritis and systemic lupus erythematosus has been tested in animal models. The aim of this research was to evaluate the effect of the water extract of S. jamaicensis leaves on psoriasis model animal (male Balb/c mice) induced topically by imiquimod. The water extract of S. jamaicensis leaves is made by boiling. The animal was divided into groups: normal, control, methotrexate 0.2 mg/kgBW, the extract (doses 25, 50 and 100 mg/kgBW). The measured parameters were the Psoriasis Area and Severity Index (PASI) score and skin histopathology. The results showed that all doses of the extract could reduce the PASI score when compared to the control group. Histological results showed that there was a decrease in keratin growth in test animals that were given the extract. Extracts at doses of 25 and 50 mg/kgBW can reduce the thickening of keratin in the epidermis of the back and ears. It can be concluded that the water extract of S. jamaicensis leaf has the most effective activity to prevent psoriasis recurrence in the dose range of 25 and 50 mg/kgBW.Keywords: Psoriasis, Stachytarpheta jamaicensis leaf water extract, PASI, keratin, imiquimod
Pengaruh Edukasi terhadap Kepatuhan Siswi Usia Remaja dalam Penggunaan Tablet Tambah Darah Debi Rianti; Suryani Suryani; Anna Choirunnisa
Inovasi Kesehatan Global Vol. 2 No. 1 (2025): Februari : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i1.1364

Abstract

This study aims to examine the effect of education on the adherence of adolescent girls to iron supplementation tablets (IST). Anemia in adolescent girls is a significant health problem, influenced by iron loss during menstruation and increased iron requirements during growth. Low adherence to IST consumption is caused by various factors, including unpleasant side effects after consuming IST, the perception of being healthy and not needing medication, and a lack of knowledge about the dangers of iron deficiency anemia in adolescence. The method used is a narrative review, with research journal sources related to the adherence of adolescent girls in consuming IST. These research journals were obtained from Google Scholar and selected those published in the last five years (2019-2023). The review results indicate the importance of education in increasing adherence to IST consumption. Audiovisual methods, such as videos and YouTube, have proven effective. Additionally, support from health workers and pharmacists is crucial in increasing the adherence of adolescent girls to IST consumption. It is concluded that innovative education and good support are essential in increasing the adherence of adolescent girls to IST consumption.
Co-Authors Afifah B. Sutjiatmo Akhirul Kahfi Syam Debi Rianti Encep Abdurahman Grace S. Mardiana Nengdiana Permana Septiani, Vina Suci Nar Vikasari, Suci Nar Suryani Suryani Sutjiatmo, Afifah Bambang