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All Journal HERBAPHARMA : Journal of Herb Farmacological AMMA : Jurnal Pengabdian Masyarakat
Indah Kurnia Utami
STIFA Pelita Mas Palu
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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UJI EKSTRAK ETANOL DAUN MIMBA (Azadirachta indica.A juss) TERHADAP KADAR KREATININ DAN UREUM TIKUS PUTIH JANTAN YANG DIINDUKSI STREPTOZOTOCIN Syafika Alaydrus; Indah Kurnia Utami; Fajar Aprilia
HERBAPHARMA : Journal of Herb Farmacological Vol 5 No 1 (2023): Volume 5 Nomor 1 Juni 2023
Publisher : STIKes Muhammadiyah Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55093/herbapharma.v5i1.395

Abstract

terjadi menyebabkan kerusakan glumerolus ginjal sehingga fungsi ginjal menurun. Kreatinin dan ureum merupakam parameter fungsi ginjal. Penelitian ini bertujuan untuk mengetahui efek dan dosis ekstrak etanol daun mimba (Azadirachta indica.A Juss) terhadap kadar kreatinin dan ureum yang diinduksi streptozotocin. Tikus dibagi menjadi 5 kelompok terdiri dari kontrol normal, kontrol negatif, kelompok perlakuan ekstrak etanol daun mimba (Azadirachta indica.A Juss) dosis 50 mg/kg BB, 100 mg/kg BB dan 150 mg/kg BB. Parameter yang diamati adalah kadar kreatinin dan ureum pada hari ke-0, 7,14, 21 dan 28. Data kreatinin dan ureum yang diperoleh dianalisis menggunakan uji one way ANOVA pada taraf kepercayaan 95% dan dilanjutkan dengan uji Post Hoc LSD. Hasil penelitian menunjukkan ekstrak etanol daun mimba pada dosis 150 mg/kg BB dapat memberikan efek terhadap penurunan kadar kreatinin dan ureum pada tikus yang diinduksi STZ, dengan nilai rata-rata kreatinin 0,72 mg/dL dan ureum 41,56 mg/dL.
SWAMEDIKASI PENGGUNAAN OBAT ALERGI SEBAGAI UPAYA MENINGKATKAN PENGETAHUAN MASYARAKAT DI DESA SEJAHTERA KECAMATAN PALOLO: SWAMEDIKASI PENGGUNAAN OBAT ALERGI SEBAGAI UPAYA MENINGKATKAN PENGETAHUAN MASYARAKAT DI DESA SEJAHTERA KECAMATAN PALOLO indah kurnia utami; Ratna Ika Yususf; niluh puspita dewi; Syafika Alaydrus
AMMA : Jurnal Pengabdian Masyarakat Vol. 1 No. 06 (2022): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Self-medication or what is known as self-medication is one of the actions that are often taken by the community to treat skin disorders. Based on a systematic review, it is known that the prevalence of self-medication in skin diseases ranges from 6-44%. Research in Togo, Africa found that 91.1% of people with skin disorders who seek treatment at health services have self-medicated before going to health services, while research conducted in Jakarta showed 44.64% of people were self-medicating for skin diseases with modern or traditional medicines. Allergies are reactions of the human immune system to certain objects, which should not cause reactions in other people's bodies. The reaction can appear in the form of a runny nose, itchy skin rash, or even shortness of breath. The drugs used by the public in self-medication of skin diseases are oral and topical drugs, including preparations containing corticosteroids, antibiotics and antifungals, a combination of salicylic acid and benzoic acid. Self-medication behavior can be influenced by knowledge, sociodemographic characteristics, family and advertising. Based on research, knowledge is the most significant factor influencing self-medication behavior.
Co-Authors Fajar Aprilia Niluh Puspita Dewi Ratna Ika Yususf Syafika Alaydrus Syafika Alaydrus