Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Althea Medical Journal
Putria Rayani Apandi, Putria Rayani
Unknown Affiliation
Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Early Left Ventricular Structural Changes With Preserved Function in Overweight and Obese Adolescents: A Speckle-Tracking Echocardiography Study Nurfandi, Wendi; Hafsah, Tisnasari; Rahayuningsih, Sri Endah; Apandi, Putria Rayani; Hakim, Dzulfikar Djalil Lukmanul; Ghrahani, Reni; Kuswiyanto, Rahmat Budi; Gurnida, Dida Akhmad
Althea Medical Journal Vol 12, No 4 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n4.4343

Abstract

Background: Overweight and obesity in adolescents are associated with dyslipidemia and may contribute to early cardiovascular remodelling. Speckle-tracking echocardiography (STE) is a sensitive imaging technique capable of detecting early myocardial functional alterations before the onset of clinical symptoms. This study aimed to evaluate the correlation between cardiac chamber dimensions, left ventricular (LV) geometry and function, and lipid profiles in overweight and obese adolescents. Methods: A cross-sectional study was conducted from June to September 2023, involving 51 overweight and obese adolescents aged 15–18 years in Bandung, Indonesia. Anthropometric measurements, fasting lipid profiles (triglycerides, total cholesterol, LDL, HDL), and transthoracic echocardiography were obtained. LV dimensions, LV mass index (LVMI), ejection fraction (EF), fractional shortening (FS), and global longitudinal strain (GLS) were assessed. Associations were analyzed using Pearson correlation.Results: Participants were predominantly male (64.7%) with a mean age of 16.3±0.6 years. Overweight (47.1%) and obesity (52.9%) were almost equally distributed with a mean BMI of 29.6±4.1 kg/m². LVMI correlated negatively with total cholesterol (r=−0.356; p=0.005), HDL (r=−0.351; p=0.006), and LDL (r=−0.280; p=0.023). The LV posterior wall thickness and LV end-diastolic diameter were also inversely correlated with selected lipid parameters. Interventricular septal thickness in systole correlated positively with triglycerides (r=0.270; p=0.028). No significant correlations were found between lipid profiles and LV function parameters, including EF, FS, and GLS (p>0.05).Conclusions: In overweight and obese adolescents, lipid profiles are associated with early alterations in LV structural dimensions while LV systolic function remains preserved. These findings support the importance of early cardiovascular screening and lifestyle modification to reduce future cardiometabolic risk.
Left Ventricular Function in Steroid-Resistant Nephrotic Syndrome At Dr. Hasan Sadikin Hospital Kusumaputri, Aghnia Ghassani; Rahayuningsih, Sri Endah; Rossanti, Rini; Apandi, Putria Rayani; Widiasta, Ahmedz
Majalah Kedokteran Bandung Vol 57, No 4 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4406

Abstract

Steroid-resistant nephrotic syndrome (SRNS) is a nephrotic syndrome (NS) which does not respond to high-dose corticosteroid therapy after 4 to 8 weeks. SRNS occurs in approximately 10–20% of childhood idiopathic nephrotic syndrome. SRNS patients are at risk of developing cardiovascular complications due to the long duration of the disease. This retrospective descriptive study investigated left ventricular function in pediatric patients with steroid-resistant nephrotic syndrome (SRNS) at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, from 2018 to 2022. A total of 42 patients aged 1 month to 18 years who underwent transthoracic echocardiography (TTE) were included. Left ventricular function was assessed using ejection fraction (EF) and fractional shortening (FS). Most patients (61.9%) had normal EF and FS values, while 38.1% showed decreased systolic function. The mean EF and FS were 55.8% and 30.2%, respectively, with median values of 59.3% and 31.2%. An important finding in this study is that some children with SRNS exhibited decreased EF and FS values despite having no other identifiable risk factors for ventricular dysfunction, such as congenital heart disease (CHD), rheumatic heart disease (RHD), chronic kidney disease (CKD), or hypertension. This finding sugest that ventricular dysfunction may still occur independently in some cases of SRNS.
Co-Authors Ahmedz Widiasta Dida Akhmad Gurnida Dzulfikar Djalil Lukmanul Hakim Kusumaputri, Aghnia Ghassani Nurfandi, Wendi Rahmat Budi Kuswiyanto, Rahmat Budi Reni Ghrahani Rossanti, Rini Sri Endah Rahayuningsih Tisnasari Hafsah, Tisnasari