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All Journal Media Dermato-Venereologica Indonesiana Journal of General-Procedural Dermatology & Venereology Indonesia
Krisanti, Inge Ade
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Health Professions Medicine & Pharmacology

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The role of dermoscopy in non-pigmented skin disorders Fathan, Hafiza; Indriatmi, Wresti; Rihatmadja, Rahadi; Krisanti, Inge Ade
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 2
Publisher : UI Scholars Hub

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Abstract

The use of dermoscopy in non-pigmented skin disorders includes dermoscopy as a diagnostic tool for non- pigmented skin tumors, inflammatory diseases (inflammoscopy) and/or infectious disease (entomodermoscopy), lesions on nail fold and as a tool to monitor skin reaction as a response to treatment and/or side effect. The diagnosis becomes easier, faster and less expensive with dermoscopy without the need for invasive procedures. Knowledge on vascular pattern and its architectural arrangement; which is coupled with additional dermoscopic features, can aid clinicians to the diagnosis. Dermatoscopy can also predict, monitor and evaluate therapeutical response and/or side effect of skin disorders. Nonetheless, dermoscopy has its limitations. Many of various non-pigmented disorders have more specific clinical features than dermoscopic ones, for clinicians to rely on to establish a diagnosis.
Langerhans cell histiocytosis: Diagnosis and Management Lusiana, Lusiana; Sjakti, Hikari Ambara; Rahmayunita, Githa; Jacoeb, Tjut Nurul Alam; Krisanti, Inge Ade
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 4, No. 1
Publisher : UI Scholars Hub

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Langerhans cell histiocytosis (LCH) is a rare disorder characterized by abnormal clonal proliferation of Langerhans dendritic cells. The incidence of LCH is 1 to 3 cases per 1 million children worldwide, and occurs most frequently in children of 1–4 years of age. The etiopathogenesis of LCH, whether it is neoplastic or reactive, is still controversial. Langerhans cell histiocytosis has a wide spectrum of clinical features, and dermatological abnormalities usually occur early. The most frequent lesions are elevated yellowish-red translucent papules about 1–2 mm in diameter and generally located in seborrheic areas. The most recent classification (the Histiocyte Society study 2017) categorized LCH into four groups; a single system with involvement of unifocal or multifocal organs, lung LCH, and multi-system LCH with either low- or high-risk multiorgan involvement. The definitive diagnosis of LCH are typical morphology along with Birbeck granules and/or positive results on CD1a antigen stain on cells found on lesions. Treatment of LCH is multimodal, determined based on age, extent of lesion, organ involvement, and organ location.
Efficacy of 3D-pore sanitary napkin on mild-to-moderate irritant contact dermatitis in the female genital area Gondokaryono, Srie Prihianti; Nilasari, Hanny; Krisanti, Inge Ade; Febrianti, Tia; Purba, Herliyani; Toyoshima, Haruko; Yunaidi, Danang Agung
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 1
Publisher : UI Scholars Hub

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Background: Women worldwide have their own strategies to cope with menstruation, and unhygienic menstrual practices often cause vaginal diseases. During menstruation, the skin is irritated by the remaining unabsorbed menstrual flow and sweat on sanitary pads. Irritation of vulvar skin by an external agent could cause contact dermatitis, which is an important contributor to vulvar diseases. Various sanitary napkins available today share similar materials. This study compared commonly used sanitary napkin among Indonesian women with 3D-pore sanitary napkin in terms of efficacy. Methods: A randomized, controlled, single blind, crossover study of 72 participants who met the inclusion and exclusion criteria was conducted. Six areas were evaluated by dermatologists using the Grading Scale of Cutaneous Symptoms. The evaluation was performed in five visits. Results: All participants were divided randomly into two groups. Eight of the 72 participants dropped out; thus, 64 participants completed the study. Scores at Visit-2 show a significant difference between group A (3D-pore napkin) and group B (comparator napkin). Group A shows better improvement. The difference in total score at first second visit until end visit from each napkin shows that the 3D-pore napkin reduces the score by 4.77 and the comparator napkin reduces the score by 3.10. The difference between these numbers is statistically significant. The specific area (external genitalia and perianal) of both groups is significantly reduced in visit 1 and visit 2. The 3D-pore napkin reduces wetness better than the comparator napkin. Conclusion: The 3D-pore sanitary napkin significantly improves vulvar skin inflammation compared with the comparator napkin.
Nevus Melanositik Didapat yang Disertai dengan Dermatitis Kronik: Tantangan Diagnosis dan Risiko Rekurensi Reshinta, Reisa; Krisanti, Inge Ade; Sirait, Sondang P.
Media Dermato-Venereologica Indonesiana Vol 52 No 1 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i1.506

Abstract

Pendahuluan: Nevus melanositik didapat merupakan lesi melanositik jinak yang paling sering ditemui. Proses peradangan kronis dapat membuat gambaran klinis dan dermoskopik nevus melanositik didapat menjadi tidak khas. Rekurensi dapat terjadi terutama pascatindakan pengangkatan lesi secara parsial. Kasus: Anak perempuan, 15 tahun, mengeluhkan tahi lalat hitam di punggung tangan kanan yang sudah ada sejak 10 tahun yang lalu. Tahi lalat membesar perlahan seiring usia, namun dalam 1 tahun terakhir terasa lebih tebal, bersisik dan gatal. Pemeriksaan dermoskopi menunjukkan gambaran tidak khas. Diagnosis nevus melanositik intradermal ditegakkan berdasarkan pemeriksaan histopatologi yang diambil dengan cara biopsi tangensial. Nevus rekuren muncul satu bulan pascaeksisi. Gambaran histopatologi menunjukkan adanya sarang-sarang sel nevus berinti bulat, vesikular, sitoplasma eosinofilik, sebagian dengan pigmen kecokelatan intrasitoplasmik, serta tidak ditemukan mitosis. Selain itu, juga terdapat akantosis, hipergranulosis, spongiosis ringan, dan vertical collagen streaks. Diskusi: Gambaran histopatologi berupa dermatitis kronik di bagian superfisial lesi dapat menjelaskan gambaran dermoskopi yang tidak khas pada nevus melanositik didapat. Pengangkatan lesi secara parsial dengan teknik biopsi tangensial meningkatkan risiko rekurensi, walaupun 23% kasus nevus rekuren ditemukan juga pascaeksisi nevus secara komplet. Gambaran klinis nevus rekuren dapat menyerupai melanoma, tetapi dermoskopi dapat membantu membedakan keduanya. Kesimpulan: Diagnosis dermatitis kronik perlu dipertimbangkan pada dermoskopi lesi nevus melanositik didapat yang tidak khas. Kemungkinan rekurensi pascaeksisi nevus melanositik didapat perlu diinformasikan kepada pasien dan/atau keluarga.
Co-Authors Danang Agung Yunaidi Fathan, Hafiza Febrianti, Tia Githa Rahmayunita Gondokaryono, Srie Prihianti Hanny Nilasari Hikari Ambara Sjakti, Hikari Ambara Jacoeb, Tjut Nurul Alam Lusiana Lusiana Purba, Herliyani Rahadi Rihatmadja Reshinta, Reisa Sirait, Sondang P. Toyoshima, Haruko Wresti Indriatmi B. Makes