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All Journal Medical Journal of Indonesia Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Bali Dermatology Venereology and Aesthetic Journal Jurnal Kedokteran Meditek
Hanny Nilasari
Departemen Dermatologi Dan Venereologi, Fakultas Kedokteran Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Sexually Transmitted Infection in Correlation with Cervical Precancerous Lesion Indarti, Junita; Kurniawan, Riyan H; Nilasari, Hanny
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.048 KB) | DOI: 10.32771/inajog.v3i1.26

Abstract

Objective: To identify the correlation between sexually transmitted infection and cervical precancerous lesion. Method: The study design is cross‐sectional. Samples were collected by consecutive sampling method until the minimal amount was fulfilled. This study was conducted in the Colposcopy Outpatient Clinic and Cytology Laboratory, Division of Specialistic Gynecology, Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital (RSCM), Jakarta, from September 2008 to March 2009. Laboratory examination for sexually transmitted infection (STI) was performed in Department of Dermatovenereology, RSCM, Jakarta. Patients were grouped into cases and control group. The case group consisted of patients diagnosed with cervical intraepithelial neoplasia (CIN) and the control group consisted of patients without CIN. Sexually transmitted infection was identified and its relationship to CIN was analyzed. Result: We included 130 patients into this study, 25.38% without CIN and 74.62% with CIN. We found that one patient can be infected by up to five types of infection at a time. We also discovered a statistically significant relation between CIN 1 and STI (p=0.028), CIN 2 and STI (p=0.007), and CIN 3 and STI (p=0.013). Conclusion: Based on our study, we discovered a significant relationship between the incidence of STI and CIN. Keywords: cervical intraepithelial neoplasia, cervical precancerous lesion, sexually transmitted infection
Sexually Transmitted Infection in Correlation with Cervical Precancerous Lesion Junita Indarti; Riyan H Kurniawan; Hanny Nilasari
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.048 KB) | DOI: 10.32771/inajog.v3i1.26

Abstract

Objective: To identify the correlation between sexually transmitted infection and cervical precancerous lesion. Method: The study design is cross‐sectional. Samples were collected by consecutive sampling method until the minimal amount was fulfilled. This study was conducted in the Colposcopy Outpatient Clinic and Cytology Laboratory, Division of Specialistic Gynecology, Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital (RSCM), Jakarta, from September 2008 to March 2009. Laboratory examination for sexually transmitted infection (STI) was performed in Department of Dermatovenereology, RSCM, Jakarta. Patients were grouped into cases and control group. The case group consisted of patients diagnosed with cervical intraepithelial neoplasia (CIN) and the control group consisted of patients without CIN. Sexually transmitted infection was identified and its relationship to CIN was analyzed. Result: We included 130 patients into this study, 25.38% without CIN and 74.62% with CIN. We found that one patient can be infected by up to five types of infection at a time. We also discovered a statistically significant relation between CIN 1 and STI (p=0.028), CIN 2 and STI (p=0.007), and CIN 3 and STI (p=0.013). Conclusion: Based on our study, we discovered a significant relationship between the incidence of STI and CIN. Keywords: cervical intraepithelial neoplasia, cervical precancerous lesion, sexually transmitted infection
BLENDED LEARNING AS A METHOD FOR IMPROVING STUDENTS’ ACHIEVEMENT IN DERMATOTHERAPY: A PRELIMINARY STUDY Sri Linuwih Menaldi; Hanny Nilasari; Githa Rahmayunita; Siti Farida; Nanda L. Prasetya
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 9, No 3 (2020): November
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.55485

Abstract

Background: Dermatotherapy is an important topic in Dermatology and Venereology module. The time allocated for dermatotherapy topic is limited, so that the development of learning method is needed to achieve the learning objectives. Blended learning is a combination of e-learning and face to face lecture session. This method is often used when there is less time available for lecturing and limited number of teachers. This learning method is expected to be more effective and efficient for the students and also the teachers. This study was conducted to examine the effectiveness of blended learning method used in dermatotherapy topic, and to identify the obstacle of using this method. Methods: This study is a cross sectional study, using quantitative and qualitative approach, involving 22 fifth-year medical students of Faculty of Medicine Universitas Indonesia who enrolled in dermatology and venereology module. We collected data from questionnaire, pre and post-test, and feedback from the students. Comparison of pre-test and post-test results were analysed using paired T test, and followed by bivariate test of students’ characteristic, gadget usage and e-learning activities associated with the increased post-test score.Results: An increased in post-test score was found to be statistically significant (p<0.05). Approximately 95,4% of students passed the final exam on the dermatotherapy subject. Bivariate analysis revealed that the number of gadgets owned, digital usage and e- learning activities did not have a significant effect on the post-test score. Based on the students’ feedback, blended learning had a positive impact on helping their learning process; however, the materials of e-learning must be interactive, informative and comprehensive. Face-to-face lecture is still an important component in learning hence it is irreplaceable. Conclusion: Blended learning is an effective method of learning and should be considered if there is limitation of lecture time and number of teachers available. By using this method, medical students are more flexible in their study and it can be adjusted to their own learning style hence heling them understand better. Further development and improvement are needed for this method as to achieve the learning objectives.  Keywords: blended learning, dermatotherapy, medical students
Prevalence of Mycoplasma hominis and Ureaplasma urealyticum infection in female sex workers and its association with douching: A study in East Jakarta, Indonesia using Mycoplasma System Plus Padang, Caroline; Jacoeb, Tjut Nurul Alam; Nilasari, Hanny; Daili, Sjaiful Fahmi
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Mycoplasma hominis and Ureaplasma urealyticum are commonly involved in pathogenesis of bacterial vaginosis and non-specific genital infection, while doing vaginal douching also already known as predisposing factor. Methods: To evaluate the prevalence of Mycoplasma hominis and Ureaplasma urealyticum infection in female sex workers and its association with vaginal douching, we conducted a study through 180 female sex workers in East Jakarta, Indonesia. Vaginal fluid samples were collected from these women. It was revealed that most of the women used betel soap, baby soap, tooth paste, or herbal medicine as vaginal douching materials. The association of vaginal douching and prevalence of Mycoplasma hominis and Ureaplasma urealyticum was analyzed using cross sectional statistical methods. Results: There is a high prevalence of Mycoplasma hominis and Ureaplasma urealyticum infection (72%), but there are no association between vaginal douching practice and infection of Mycoplasma hominis and Ureaplasma urealyticum. Conclusions: The high prevalence of Mycoplasma hominis and Ureaplasma urealyticum infection in female sex workers in East Jakarta warrants a routine screening of these infections. Unusual1 materials used for vaginal douching in this study might cause the negative association between high prevalence of these bacteria with vaginal douching.
Venous Ulcer Santoso, Irene Dorthy; Nilasari, Hanny; Yusharyahya, Shannaz Nadia
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 2
Publisher : UI Scholars Hub

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Abstract

Leg ulcers one common problem in the adult population to geriatric with a prevalence about 1-2%. The pattern of life which tends to be sedentary, less activity, obesity, increased the incidence of leg ulcers. The duration of healing and recurrence occurs in majority of patients contributed the decline in quality of life for patients with venous ulcers. Diagnosis, latest treatment and prevention are essential to discuss.
Vaginal microbiota in menopause Martinus, Martinus; Wibawa, Larisa Paramitha; Effendi, Evita Halim; Yusharyahya, Shannaz Nadia; Nilasari, Hanny; Indriatmi, Wresti
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 3
Publisher : UI Scholars Hub

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Abstract

The human vagina together with its resident, microbiota, comprise a dynamic ecosystem. Normal microbiota is dominated by Lactobacillus species, and pathogen microbiota such as Gardnerella species and Bacteroides species can occur due to decrease in Lactobacillus domination. Lactobacillus plays an essential role in keeping normal vaginal microbiota in balance. Vaginal microbiota adapts to pH change and hormonal value. Changes in the vaginal microbiota over a woman’s lifespan will influence the colonization of pathogenic microbes. They include changes in child, puberty, reproductive state, menopause, and postmenopause. Estrogen levels change will affect the colonization of pathogenic microbium, leading to genitourinary syndrome of menopause. Vulvovaginal atrophy is often found in postmenopausal women, and dominated by L. iners, Anaerococcus sp, Peptoniphilus sp, Prevotella sp, and Streptococcus sp. The normal vaginal microbiota’s imbalance in menopause will cause diseases such as bacterial vaginosis, and recurrent vulvovaginal candidiasis due to hormonal therapies. Changes in the vaginal microbiota due to bacterial vaginosis are characterized by decrease in H2O2-producing Lactobacillus. They are also caused by the increase in numbers and concentration of Gardnerella vaginalis, Mycoplasma hominis, and other anaerob species such as Peptostreptococci, Prevotella spp, and Mobiluncus spp.
Pulsed-dye laser efficacy in the treatment of psoriasis in adult patients: An evidence-based case report Krisna, Made Ananda; Nilasari, Hanny
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 3
Publisher : UI Scholars Hub

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Abstract

Psoriasis is a chronic inflammatory skin disease known to be highly responsive to phototherapy. Narrow-band UVB (NBUVB) phototherapy has been one of the standard treatments for its moderate to severe form. However, its lack of efficacy in treating stable psoriatic plaques on extremities has lead researchers to find alternative treatments, one of which is pulsed-dye laser (PDL). Laser has been known to be effective in treating vascular lesions; in psoriasis, elongation of rete ridge along with tortuous dermal capillaries are one of the first pathologies identified early in the disease progression. Several in vivo and preliminary studies have found the molecular mechanism of action of laser on abnormal vessel growth. In this article, we report a psoriasis vulgaris case in adult whose lesions responded well to NBUVB phototherapy. The psoriatic plaques on her extremities were stable despite NBUVB therapy and some topical treatments afterwards. With knowledge of emerging role of PDL in inflammatory skin disease such as psoriasis, we conducted a literature search and critically appraised the resulting articles. The systematic review article found evaluates PDL efficacy as a treatment for inflammatory skin diseases, including psoriasis, and was appraised using a worksheet from British Medical Journal Evidence-Based Medicine Toolkit. Its validity, importance, and applicability aspects were evaluated, leading to a conclusion that PDL can be used as an alternative treatment for psoriasis plaques in trunks, extremities, hands, or feet (both stable and unstable), with minimal and transient side effects (hyperpigmentation, hypopigmentation, and blistering).
Ulcus vulvae acutum - A rare case Santoso, Irene Dorthy; Anggraini, Ika; Indriatmi, Wresti; Irawan, Yudo; Nilasari, Hanny; Marissa, Melani; Sirait, Sondang P.; Rihatmadja, Rahadi
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Ulcus vulvae acutum, also known as Lipschütz ulcer, is a rare condition characterized by multiple, painful, and acute genital ulceration in young women without venereal infections, associated with systemic symptoms like malaise, fever, and inguinal lymphadenopathy. Case Illustration: A 24-year-old woman developed multiple and painful vulvar ulcers that recurred for almost a year. The patient was primarily diagnosed and treated as genital herpes in several hospitals with only slight improvement and no complete healing. The patient came to our hospital for examinations to rule out sexually-transmitted infection (STI) (genital herpes, syphilis, HIV, and chancroid) and possibility of Behçet’s. The patient was treated with a combination of 2.5% lidocaine and 2.5% prilocaine creams for 1 week, 2% fusidic acid ointment for 1 week, with no significant progression. Later, the therapy was changed to 0.05% clobetasol propionate ointment for 10 days. Complete healing occurred in about 10 weeks with no scarring. Discussion: Diagnosis of ulcus vulvae acutum in this patient was made by excluding other differential diagnoses. Conclusion: Ulcus vulvae acutum is a difficult diagnosis, and clinician should be aware of this entity especially when encountering young woman without previous sexual experience problem with ulcer.
Recurrent perianal wart therapy with 90% trichloroacetate (TCA) solution in AIDS patients Menaldi, Sri Linuwih SW; Anggraini, Ika; Nilasari, Hanny
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Being the most commonly found sexually-transmitted infection (STI), anogenital warts are mainly caused by human papilloma virus (HPV) type 6 and 11. These infections are often recurrent, leading to loss of time and medical expenses. Various therapeutic modalities can be chosen singularly or in combination with varying results. Treatments with less responsive results usually occur when acquired comorbidities are present, such as HIV infection. Case Illustration: A 28-year-old homosexual male was reported to have a recurrent perianal wart for the duration of eight months. He was also diagnosed with AIDS and pulmonary tuberculosis. Initially, patient was treated with 25% podophyllin tincture, but there was no improvement. Patient was known to still practicing high-risk sexual behavior. After six treatments of TCA, the warts shrank gradually and no new warts had grown. Discussion: It was found that there is a strong relationship between high incidences of genital warts with reduced immune function due to by HIV infection. Patients infected with HIV will often experience recurrence and needs longer treatment. In this case ARV treatment is given and followed by increase in CD4 count, thereby increasing the effectiveness of the treatment of perianal warts. Conclusion: As recommended by clinical guideline in Indonesia, 90% TCA is proven to be effective in treating recurrent anogenital warts in this case. It is important to counsel the patient regarding the sexual behavior for him and his sexual partner, as it will affect the patient’s prognosis significantly.
Efficacy of 3D-pore sanitary napkin on mild-to-moderate irritant contact dermatitis in the female genital area Gondokaryono, Srie Prihianti; Nilasari, Hanny; Krisanti, Inge Ade; Febrianti, Tia; Purba, Herliyani; Toyoshima, Haruko; Yunaidi, Danang Agung
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Women worldwide have their own strategies to cope with menstruation, and unhygienic menstrual practices often cause vaginal diseases. During menstruation, the skin is irritated by the remaining unabsorbed menstrual flow and sweat on sanitary pads. Irritation of vulvar skin by an external agent could cause contact dermatitis, which is an important contributor to vulvar diseases. Various sanitary napkins available today share similar materials. This study compared commonly used sanitary napkin among Indonesian women with 3D-pore sanitary napkin in terms of efficacy. Methods: A randomized, controlled, single blind, crossover study of 72 participants who met the inclusion and exclusion criteria was conducted. Six areas were evaluated by dermatologists using the Grading Scale of Cutaneous Symptoms. The evaluation was performed in five visits. Results: All participants were divided randomly into two groups. Eight of the 72 participants dropped out; thus, 64 participants completed the study. Scores at Visit-2 show a significant difference between group A (3D-pore napkin) and group B (comparator napkin). Group A shows better improvement. The difference in total score at first second visit until end visit from each napkin shows that the 3D-pore napkin reduces the score by 4.77 and the comparator napkin reduces the score by 3.10. The difference between these numbers is statistically significant. The specific area (external genitalia and perianal) of both groups is significantly reduced in visit 1 and visit 2. The 3D-pore napkin reduces wetness better than the comparator napkin. Conclusion: The 3D-pore sanitary napkin significantly improves vulvar skin inflammation compared with the comparator napkin.
Co-Authors Adisasmito, Ayutika Saraswati Anggraini, Ika Aria Kekalih Asep Purnama Azizah, Anggita Nur Banunaek, Diana Chelsea, Edelyne Cornain, Emilina Faradila Danang Agung Yunaidi Evita Halim Effendi Eyleny Meisyah Fitri Febrianti, Tia Githa Rahmayunita Gondokaryono, Srie Prihianti Halim, Melissa Hartono Gunardi Haswinzky, Rose Amalia Hutasuhut, Magna Fitriani Irawan, Yudo Jacoeb, Tjut Nurul Alam Jhauharina Rizki Fadhilla Junita Indarti Kayika, I Putu Gede Kemal N. Siregar Krisanti, Inge Ade Krisanti, Roro Inge Ade Krisna, Made Ananda Kurniawan, Kristian Larisa Paramitha Lesmana, Elvira Lidwina Anissa Lili Legiawati Manurung, Edward Sugito Marissa, Melani Martinus, Martinus Melinda, Thong Felicia Menaldi, Sri Linuwih Susetyo Wardhani Menaldi, Sri Linuwih SW Miranda, Eliza Nanda L. Prasetya Natalia Rania Sutanto Noer Kamila Nur Azizah, Anggita Padang, Caroline Purba, Herliyani Rahadi Rihatmadja Raymond Surya Rinadewi Astriningrum Riyan H Kurniawan Riyan H Kurniawan, Riyan H Sandra Widaty Santoso, Irene Dorthy Saroyo, Yudianto Budi Shannaz Nadia Yusharyahya Shannaz Nadia Yusharyahya Sirait, Sondang P. Siti Farida Sjaiful Fahmi Daili Sri Linuwih Susetyo Wardhani, Sri Linuwih Susetyo Toyoshima, Haruko Triana Agustin Windy Atika Hapsari, Windy Atika Wresti Indriatmi B. Makes Yudo Irawan